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TLSATiziana Life Sciences Ltd
$1.26$80M
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TLSA logoTiziana Life Sciences Ltd(TLSA)Earnings, Financials & Key Ratios

TLSA•NASDAQ
$1.26
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryImmunology and Inflammation Therapies
AboutTiziana Life Sciences Ltd, a biotechnology company, focuses on the discovery and development of molecules to treat human diseases in oncology and immunology. The company's lead product candidate in immunology is Foralumab (TZLS-401), a human anti-CD3 monoclonal antibody (mAb) for the treatment of Crohn's, graft versus host, ulcerative colitis, multiple sclerosis, type-1 diabetes, inflammatory bowel, psoriasis, and rheumatoid arthritis diseases. It also develops Milciclib (TZLS-201), a small molecule inhibitor of various cyclin-dependent kinases, tropomycin receptor kinases, and Src family kinases controlling cell growth and malignant progression of cancer; and anti-Interleukin 6 receptor (IL6R) mAb (TZLS-501), a fully human monoclonal antibody for the treatment of IL6-induced inflammation and to treat COVID-19 patients. The company was incorporated in 1998 and is headquatered in London, the United Kingdom.Show more
  • Revenue$0
  • EBITDA-$21M-34.3%
  • Net Income-$18M-55.4%
  • EPS (Diluted)-0.32-45.5%
  • ROE-924.32%-269.0%

TLSA Price & Volume

Tiziana Life Sciences Ltd (TLSA) stock price & volume — 10-year historical chart

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Clinical Development Costs Threaten Capital Base Sustainability

Investment Thesis • Updated 2025Q4

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Imminent liquidity and dilution

Key Thesis Takeaways

  • Tiziana Life Sciences remains a pre-revenue biotechnology entity entirely dependent on external financing to sustain its intranasal Foralumab clinical pipeline.
  • The company faces significant solvency risks as its equity base has eroded to a nominal $52.0K, necessitating potential dilutive capital raises to address the $12.3M operating loss recorded in 2025Q4.
  • Investors should monitor the firm's ability to secure non-dilutive funding, as the current $4.0M cash position provides a limited runway for ongoing research activities.

Verdict Logic

the company's rapid erosion of its asset base from $57.9M in 2021Q2 to $11.5M in 2025Q4, combined with a critical liquidity position, suggests substantial risk of further shareholder dilution.

TLSA Growth Metrics

Tiziana Life Sciences Ltd (TLSA) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM10.02%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM17.27%

Return on Capital

10 Years-996.52%
5 Years-329.25%
3 Years-505.5%
Last Year-1008.24%

TLSA Recent Earnings

Tiziana Life Sciences Ltd (TLSA) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 0/12 qtrs (0%)
Q2 2026Latest
May 1, 2026
Metric
Actual
Est
EPS
$0.22-143.0%
$0.09
Rev
—
—
Q3 2025
Jul 8, 2025
Metric
Actual
Est
EPS
$0.10-35.4%
$0.07
Rev
—
—
Q3 2025
Jun 23, 2025
Metric
Actual
Est
EPS
$0.13
—
Rev
—
—
Q2 2025
May 20, 2025
Metric
Actual
Est
EPS
$0.06
—
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 1, 2026
$0.22vs $0.09-143.0%
—
Q3 2025Jul 8, 2025
$0.10vs $0.07-35.4%
—
Q3 2025Jun 23, 2025
$0.13
—
Q2 2025May 20, 2025
$0.06
—
Based on last 12 quarters of dataView full earnings history →

Latest TLSA News

Recent stock market news and headlines for Tiziana Life Sciences Ltd (TLSA)

Proactive Investors - Finance·Jun 25, 2026
Qualcomm raises long-term targets as analysts highlight data center, edge AI opportunities

Qualcomm Inc (NASDAQ:QCOM, XETRA:QCI) outlined higher long-term revenue and earnings targets at its investor day, prompting analysts at Bank of America and...

Proactive Investors·Jun 25, 2026
Tiziana Life Sciences doses last patient in Phase 2a multiple sclerosis trial

Tiziana Life Sciences Ltd (NASDAQ:TLSA) said the last patient in its Phase 2a clinical trial has received a first dose of intranasal foralumab for the treatment of non-active Secondary Progressive Multiple Sclerosis (na-SPMS), with topline data expected in late Q3 or early Q4 2026. The company said results are planned to be presented at the 10th joint ACTRIMS-ECTRIMS meeting in Toronto in October 2026.

GlobeNewsWire·Jun 25, 2026
Tiziana Announces Last Patient Successfully Dosed in its Phase 2 INFORM-MS Trial

Top line data readout expected in late Q3/early Q4 INFORM-MS trial is a randomized, double-blind, placebo-controlled Phase 2a trial using Intranasal Foralumab in patients with Non-Active Secondary Progressive Multiple Sclerosis BOSTON, June 25, 2026 (GLOBE NEWSWIRE) -- Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana”), a biotechnology company developing its lead candidate, intranasal foralumab, a fully human, anti-CD3 monoclonal antibody, announces that the last patient in its ongoing Phase 2a clinical trial has received their first dose of intranasal foralumab for the treatment of non-active Secondary Progressive Multiple Sclerosis (na-SPMS).

Peers Comparison

Key metrics vs top competitors for Tiziana Life Sciences Ltd (TLSA)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
TLSA logoTLSATiziana Life Sciences LtdCurrent
$1.26$80.17M-3.94——-924.32%—
IMVT logoIMVTImmunovant, Inc.
$40.09$8.23B-14.47——-68.16%—
ARCT logoARCTArcturus Therapeutics Holdings Inc.
$7.60$216.02M-3.17-51.43%-173.47%-36.55%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$323.95$9.36B-24.03-100%—-43.02%—
KYMR logoKYMRKymera Therapeutics, Inc.
$119.24$9.74B-32.31-16.72%-612.17%-25.02%—
RCUS logoRCUSArcus Biosciences, Inc.
$30.25$3.05B-9.19-4.26%-156.36%-68.97%—

Compare TLSA vs Peers

Tiziana Life Sciences Ltd (TLSA) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IMVT

Most directly comparable listed peer for TLSA.

Scale Benchmark

vs MEDP

Larger-name benchmark to compare TLSA against a more recognizable public peer.

Peer Set

Compare Top 5

vs IMVT, ARCT, PRAX, KYMR

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TLSA Frequently Asked Questions

Tiziana Life Sciences Ltd (TLSA) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is TLSA profitable?

Tiziana Life Sciences Ltd (TLSA) reported a net loss of $34.9M for fiscal year 2025.

Dividend & Returns
What is TLSA's return on equity?

Tiziana Life Sciences Ltd (TLSA) has a return on equity (ROE) of -924.3%. Negative ROE indicates the company is unprofitable.

What is Tiziana Life Sciences Ltd's free cash flow?

Tiziana Life Sciences Ltd (TLSA) had negative free cash flow of $14.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in TLSA back in 1998?

Total return calculator · dividends reinvested · 28+ years of data

See returns →