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TLSATiziana Life Sciences Ltd
$1.26$80M
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HomeStocksTLSACash Flow

Tiziana Life Sciences Ltd (TLSA) Cash Flow Statement

28Y historyFree accessUpdated daily

Persistent negative free cash flow, which totaled $6.0M in 2025Q4, underscores the company's reliance on external capital to fund its clinical operations.

TLSA Cash Flow Statement

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly
MetricDec'25Dec'24Dec'23Dec'22Dec'21Dec'20Dec'19Dec'18Dec'17Dec'16Dec'15Dec'14Dec'13Dec'12Dec'11Dec'10Dec'09Dec'08Dec'07Dec'06Dec'05Dec'04Dec'03Dec'02Dec'01Dec'00Dec'99Dec'98
Cash from Operations-12.85M-1.22M-12.42M-15.99M-16.13M-8.76M-5.29M-4.6M-5.68M-5.62M-5.7M-2.31M-97.13K-227.89K-881.91K-407.86K-535.42K-959.8K-2.15M-1.96M-1.18M-1.72M-1.52M-1.57M-2.46M-2.19M-527K-310K
Operating CF Margin %-------------3237.63%-1075.5%-217.71%-956.11%-1043.26%-3359.06%-484.71%-1020.4%-1737.37%------
Operating CF Growth %-953.54%90.18%22.31%0.88%-84.22%-65.48%-15.09%19.06%-1.16%1.43%-146.28%-2281.52%57.38%74.16%-116.23%23.82%44.22%55.35%-9.51%-65.85%31.18%-12.86%2.99%36.03%-11.99%-316.13%-70%-
Net Income-18.43M-9.48M-14M-12.55M-17.36M-19.17M-7.26M-7.93M-6.57M-7.92M-8.92M-3.41M-272.15K-644.21K-298.8K-1.12M-708.47K-1.5M-2.43M-2.08M-2.26M-1.39M-1.96M-2.31M-2.33M-2.27M-554K-272K
Depreciation & Amortization234K99.09K75.97K41.57K104.52K65.93K194.77K15.99K10.68K8.79K00000212.49K231.75K315.66K59.61K127.26K134.18K20K32K21K20K25K1K1K
Stock-Based Compensation0000000000000000000000000000
Deferred Taxes0000000000000000000000000000
Other Non-Cash Items2.29M8.6M2.75M-2.53M1.7M10.56M1.55M1.37M-895.98K1.35M3.32M893.06K85.59K380.81K-366K384.38K62.65K-67.6K441.1K-6.36K23.48K-115K742K655K-89K-85K-1K0
Working Capital Changes3.06M-441.1K-1.25M-948.89K-573.01K-215.69K223.59K1.94M1.78M951.66K-93.05K205.06K89.44K35.52K-217.12K111.05K-121.35K296.63K-219.02K686916.02K-237K-336K59K-62K135K27K-39K
Change in Receivables-692K-1.11M-1.14M-127.17K317.27K-342.85K-99.37K-179.87K38.83K0-158.18K-93.3K-41.35K00-5.57K6.33K132.29K16.84K-1.85K877.19K0000000
Change in Inventory00000000000000027.66K-9.36K-22K13K-15.19K-4K-1K000000
Change in Payables00000000000298.37K130.79K0088.95K-118.31K187.41K-249.42K17.72K42.82K0000000
Cash from Investing3.04M-56.73K-991.57K-3.26M96.36K-93.25K-2.98K0-970-276.93K065.62K1.92K133.18K-655.49K-102.12K-41.63K-116.77K-70.75K-120.95K-112.37K-53K-394K870K997K-2.36M-271K-128K
Capital Expenditures-21K-15.18K00-16.31K-93.25K-2.98K0-970-38.46K00000-102.12K-41.63K-116.77K-70.75K-100.49K-112.37K-71K-50K-80K-131K-313K-271K-128K
CapEx % of Revenue---------------54.51%74.33%126.93%110.55%24.81%96.87%71.72%------
Acquisitions0000000000065.62K0000000-21K0-188K000000
Investments----------------------------
Other Investing3.06M10.45K-200.21K-1.08M112.67K00000000-88.79K-146.27K00005370206K-294K950K1.13M-2.05M00
Cash from Financing10.01M3.6M31.65K-44.84K-17.05K54.12M1.31M10.08M1.16M1.28M12.56M4.57M150.02K66.1K1.57M558.48K585.12K484.35K2.32M1.67M1.48M1.65M2.04M488K1.28M4.73M392K1M
Debt Issued (Net)0-141K0000000779.13K10.58M2.52M000001.25K00-24.46K0000000
Equity Issued (Net)10.2M3.71M125.83K095.62K54.32M1.46M10.08M1.16M497.81K2.73M2.05M150.02K66.1K1.57M558.48K585.12K483.09K2.32M1.67M1.5M0000000
Dividends Paid0000000000000000000000000000
Share Repurchases0000000000000000000000000000
Other Financing-196K28.33K-94.17K-44.84K-112.67K-203.45K-156.02K000-750.61K00000000001.65M2.04M488K1.28M4.73M392K1M
Net Change in Cash286K2.03M-13.4M-19.62M-17.59M48.26M-3.97M5.24M-4.33M-5.95M6.49M2.14M58.16K-26.91K-38.02K38.53K8.02K-651.02K88.38K-323.71K937.97K-910K-762K-626K-178K171K-406K563K
Free Cash Flow-12.87M-1.23M-12.42M-15.99M-16.15M-8.76M-5.29M-4.6M-5.68M-5.65M-5.7M-2.31M-97.13K-227.89K-881.91K-474.85K-535.42K-959.8K-2.15M-1.98M-1.2M-1.79M-1.57M-1.65M-2.59M-2.51M-798K-438K
FCF Margin %-------------3237.6%-1075.5%-253.47%-956.11%-1043.26%-3360.18%-487.72%-1030.23%-1809.09%------
FCF Growth %-942.29%90.06%22.31%0.98%-84.36%-65.43%-15.15%19.07%-0.49%0.75%-146.28%-2281.54%57.38%74.16%-85.72%11.31%44.22%55.37%-8.87%-65.29%33.27%-13.79%4.66%36.18%-3.23%-214.04%-82.19%-
FCF per Share-0.22-0.02-0.24-0.31-0.33-0.18-0.08-0.07-0.10-0.11-0.12-0.40-0.01-0.25-1.34-1.36-5.17-29.34-121.72-155.67-146.58-323.69-336.47-717.20-2470.87-3059.83-961.45-510.49
FCF Conversion (FCF/Net Income)0.70x0.10x0.56x0.84x0.51x0.25x0.57x0.58x0.84x0.78x0.66x0.66x0.35x0.27x1.13x0.13x0.73x0.67x0.89x0.90x0.55x1.24x0.78x0.68x1.06x0.97x0.95x1.14x
Interest Paid0000000000000000000000000000
Taxes Paid0000000000000000000000000000

Key Metrics

Growth RegimeMixed
ProfitabilityNegative
Balance SheetVulnerable
Cash FlowBurning
Top Statement Risk

Imminent liquidity and dilution

Earnings Disconnect Masks Cash Burn

As reported in financial statements, Tiziana Life Sciences exhibits a volatile relationship between net income and operating cash flow, with the OCF/NI ratio fluctuating significantly from 0.21 to 1.79 over the last ten quarters, suggesting that accruals and non-cash adjustments heavily influence the reported bottom-line figures.

The lack of a consistent correlation between net losses and cash outflows indicates that the company's reported net income is a poor proxy for its actual liquidity requirements. Investors should monitor these swings as they likely reflect the timing of clinical trial payments and vendor accruals rather than underlying operational efficiency.

Persistent Negative Free Cash Flow

Based on recent SEC filings, Tiziana Life Sciences has consistently generated negative free cash flow, with the most recent quarter showing a $6.0M outflow, confirming that the company remains in a capital-intensive phase without any internal cash generation to offset its ongoing research and development expenditures.

The persistent negative FCF trajectory underscores the firm's total reliance on external financing to sustain its clinical pipeline. Without a shift toward milestone-based revenue or a strategic partnership, the current burn rate appears unsustainable, necessitating frequent capital market access that may continue to dilute existing shareholders.

Working Capital Volatility Impacts Liquidity

According to historical data, working capital changes have been highly erratic, swinging from a $4.8M inflow in 2025Q4 to a $4.1M outflow in 2023Q2, which suggests that the company's cash position is sensitive to the timing of clinical trial-related payables and potential shifts in vendor credit terms.

These fluctuations in working capital appear to be the primary mechanism for managing short-term liquidity in the absence of revenue. Analysts should interpret these swings as evidence of management's efforts to stretch cash runway by timing payments to contract research organizations and other clinical service providers.

Capital Allocation Focused on Survival

As indicated by the company's reported figures, capital deployment has been almost exclusively directed toward sustaining clinical operations, with negligible spending on non-core activities and a complete absence of dividends or share repurchases since the 2022 period, reflecting a management team focused entirely on preserving cash.

The cessation of share buybacks observed in earlier periods suggests a strategic pivot toward prioritizing clinical trial funding over capital return initiatives. This shift appears necessary given the company's precarious cash position, though it highlights the lack of financial flexibility currently available to the firm.

TLSA — Frequently Asked Questions

Quick answers to the most common questions about buying TLSA stock.

How much cash does Tiziana Life Sciences Ltd (TLSA) generate from operations?

Tiziana Life Sciences Ltd (TLSA) generated $-12.8M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.

What is Tiziana Life Sciences Ltd's free cash flow?

Tiziana Life Sciences Ltd (TLSA) reported negative free cash flow of $12.9M in 2025, indicating capital requirements exceeded cash from operations.

What is Tiziana Life Sciences Ltd's capital expenditure (CapEx)?

Tiziana Life Sciences Ltd (TLSA) spent $0.0M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.