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RCUSArcus Biosciences, Inc.
$30.25$3.0B
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RCUS logoArcus Biosciences, Inc.(RCUS)Earnings, Financials & Key Ratios

RCUS•NYSE
$29.98
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutArcus Biosciences, Inc., a clinical-stage biopharmaceutical company, develops and commercializes cancer therapies in the United States. Its product pipeline includes, Etrumadenant, a dual A2a/A2b adenosine receptor antagonist, which is in a Phase 1b/2 clinical trial; and Zimberelimab, an anti-PD-1 antibody that is in Phase 1b clinical trial for monotherapy. The company also develops Domvanalimab, an anti-TIGIT monoclonal antibody, which is in Phase 2 development for the treatment of first-line metastatic non-small cell lung cancer in combination with Zimberelimab; Quemliclustat, a small-molecule CD73 inhibitor is in a Phase 1/1b study for the treatment of first-line metastatic pancreatic cancer; and AB521, an oral and small molecule HIF-2a inhibitor that is in Phase 1 study for the treatment of patients with von Hippel- Lindau disease. It has a clinical development collaboration agreement with Strata Oncology, Inc. to evaluate Zimberelimab; a collaboration with AstraZeneca, BVF Partners L.P to evaluate domvanalimab, its investigational anti-TIGIT antibody, in combination with Imfinzi (durvalumab) in a registrational Phase 3 clinical trial in patients with unresectable Stage III non-small cell lung cancer; and license agreements with Taiho Pharmaceutical Co., Ltd, Abmuno Therapeutics LLC, and WuXi Biologics to develop anti-CD39 antibody for the treatment of cancer. The company was incorporated in 2015 and is headquartered in Hayward, California.Show more
  • Revenue$247M-4.3%
  • EBITDA-$376M-17.5%
  • Net Income-$353M-24.7%
  • EPS (Diluted)-3.29-4.8%
  • Gross Margin95.95%-4.0%
  • EBITDA Margin-152.23%-22.7%
  • Operating Margin-156.28%-22.2%
  • Net Margin-142.91%-30.3%
  • ROE-63.26%-5.8%

RCUS Price & Volume

Arcus Biosciences, Inc. (RCUS) stock price & volume — 10-year historical chart

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Clinical Milestone Dependency Strains Capital Liquidity Runway

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical Milestone Funding Dependency

Key Thesis Takeaways

  • Arcus Biosciences faces a precarious financial outlook as its multi-node immuno-oncology pipeline requires consistent, high-level R&D spending that frequently exceeds $100 million per quarter.
  • The company's reliance on volatile, milestone-driven revenue from its Gilead partnership creates significant earnings unpredictability, while the exhaustion of deferred revenue—dropping from $398 million in 2023Q4 to $34 million in 2026Q1—threatens long-term operational sustainability.
  • Investors should monitor the firm's ability to secure additional capital or achieve critical clinical milestones, as the current cash burn trajectory and rising debt load suggest a narrowing window for self-funded development.

Verdict Logic

the company's reliance on milestone-driven revenue and a declining cash balance of $201 million in 2026Q1, coupled with a negative $1.6 billion in retained earnings, suggests significant risk to long-term shareholder value.

RCUS Growth Metrics

Arcus Biosciences, Inc. (RCUS) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years25.93%
3 Years30.16%
TTM67.38%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM5.63%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM24.6%

Return on Capital

10 Years-27.85%
5 Years-25.52%
3 Years-37.02%
Last Year-42.14%

RCUS Recent Earnings

Arcus Biosciences, Inc. (RCUS) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (67%)●Beat Revenue 7/12 qtrs (58%)
Q2 2026Latest
May 5, 2026
Metric
Actual
Est
EPS
$1.02-10.9%
$0.92
Rev
$17M-42.3%
$29M
Q1 2026
Feb 25, 2026
Metric
Actual
Est
EPS
$0.89+19.8%
$1.11
Rev
$33M-7.6%
$36M
Q4 2025
Oct 28, 2025
Metric
Actual
Est
EPS
$1.27+4.5%
$1.33
Rev
$26M+4.3%
$25M
Q3 2025
Aug 6, 2025
Metric
Actual
Est
EPS
$0.08+93.4%
$1.14
Rev
$160M+392.6%
$32M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 5, 2026
$1.02vs $0.92-10.9%
$17Mvs $29M-42.3%
Q1 2026Feb 25, 2026
$0.89vs $1.11+19.8%
$33Mvs $36M-7.6%
Q4 2025Oct 28, 2025
$1.27vs $1.33+4.5%
$26Mvs $25M+4.3%
Q3 2025Aug 6, 2025
$0.08vs $1.14+93.4%
$160Mvs $32M+392.6%
Based on last 12 quarters of dataView full earnings history →

Latest RCUS News

Recent stock market news and headlines for Arcus Biosciences, Inc. (RCUS)

Business Wire·6 days ago
New Research Published in Nature Links Clinical Activity with HIF‑2a Biology in Advanced Kidney Cancer Patients Treated with Casdatifan

HAYWARD, Calif.--(BUSINESS WIRE)--Arcus Biosciences, Inc. (NYSE: RCUS), a clinical-stage, global biopharmaceutical company focused on developing differentiated molecules and combination therapies for people with cancer and inflammatory and autoimmune diseases, today announced a publication in Nature describing new research from the ARC-20 study. The publication evaluated casdatifan, an investigational, small-molecule HIF-2a inhibitor, as a monotherapy in patients with metastatic clear cell rena.

Business Wire·Jun 24, 2026
Arcus Biosciences Announces New Employment Inducement Grants

HAYWARD, Calif.--(BUSINESS WIRE)--Arcus Biosciences, Inc. (NYSE:RCUS), a clinical-stage, global biopharmaceutical company focused on developing differentiated molecules and combination therapies for people with cancer and inflammatory and autoimmune diseases, today announced that the Compensation Committee of the Company's Board of Directors granted two new employees options to purchase a total of 18,400 shares of the Company's common stock at an exercise price per share of $28.18, which was the.

Peers Comparison

Key metrics vs top competitors for Arcus Biosciences, Inc. (RCUS)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
RCUS logoRCUSArcus Biosciences, Inc.Current
$29.98$3.02B-9.11-4.26%-142.91%-63.26%—
AGEN logoAGENAgenus Inc.
$3.41$142M-1002.9410.37%52.16%——
EXEL logoEXELExelixis, Inc.
$55.53$14.11B19.976.98%35.08%40.21%—
HALO logoHALOHalozyme Therapeutics, Inc.
$80.78$9.58B31.5537.55%23.13%126.27%—
FOLD logoFOLDAmicus Therapeutics, Inc.
$14.49$4.55B-164.8520.05%-4.27%-12.02%—
TGTX logoTGTXTG Therapeutics, Inc.
$53.52$8.19B19.3287.32%65.95%87.36%—

Compare RCUS vs Peers

Arcus Biosciences, Inc. (RCUS) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs AGEN

Most directly comparable listed peer for RCUS.

Scale Benchmark

vs MRK

Larger-name benchmark to compare RCUS against a more recognizable public peer.

Peer Set

Compare Top 5

vs AGEN, EXEL, HALO, FOLD

RCUS SEC Filings & Documents

Arcus Biosciences, Inc. (RCUS) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 5, 2026·SEC

Material company update

Apr 20, 2026·SEC

Material company update

Mar 23, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 25, 2026·SEC

FY 2025

Feb 25, 2025·SEC

FY 2024

Feb 21, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 5, 2026·SEC

FY 2025

Oct 28, 2025·SEC

FY 2025

Aug 6, 2025·SEC

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RCUS Frequently Asked Questions

Arcus Biosciences, Inc. (RCUS) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Arcus Biosciences, Inc.'s revenue?

Arcus Biosciences, Inc. (RCUS) reported $236.0M in revenue for fiscal year 2025.

How fast is Arcus Biosciences, Inc. growing?

Arcus Biosciences, Inc. (RCUS) saw revenue decline by 4.3% over the past year.

Is RCUS profitable?

Arcus Biosciences, Inc. (RCUS) reported a net loss of $369.0M for fiscal year 2025.

Dividend & Returns
What is RCUS's return on equity?

Arcus Biosciences, Inc. (RCUS) has a return on equity (ROE) of -63.3%. Negative ROE indicates the company is unprofitable.

What is Arcus Biosciences, Inc.'s free cash flow?

Arcus Biosciences, Inc. (RCUS) had negative free cash flow of $489.0M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in RCUS back in 2016?

Total return calculator · dividends reinvested · 10+ years of data

See returns →