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Exelixis, Inc. (EXEL) stock price & volume — 10-year historical chart
Investment Thesis • Updated 2026Q1
while the company maintains a healthy balance sheet and a 15.55 forward P/E ratio, the material risk of generic litigation and volatile cash flow generation warrants a cautious approach.
Exelixis, Inc. (EXEL) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR
Exelixis, Inc. (EXEL) EPS & revenue vs analyst estimates — last 4 quarters
| Quarter | Date | EPS (Act vs Est) | Revenue (Act vs Est) |
|---|---|---|---|
| Q2 2026Latest | May 5, 2026 | $0.87vs $0.77+13.7% | $611Mvs $608M+0.5% |
| Q1 2026 | Feb 10, 2026 | $0.94vs $0.77+22.1% | $599Mvs $597M+0.4% |
| Q4 2025 | Nov 4, 2025 | $0.78vs $0.69+13.9% | $598Mvs $590M+1.3% |
| Q3 2025 | Jul 28, 2025 | $0.75vs $0.65+15.4% | $568Mvs $595M-4.5% |
Recent stock market news and headlines for Exelixis, Inc. (EXEL)
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Exelixis falls after STELLAR-303 misses statistical significance in overall survival for a key colorectal cancer subgroup, raising approval uncertainty.

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ALAMEDA, Calif.--(BUSINESS WIRE)--Exelixis, Inc. (Nasdaq: EXEL) today announced results from the final analysis of the dual primary endpoint of overall survival (OS) in the subset of patients without active liver metastases (non-liver metastases, NLM) in the phase 3 STELLAR-303 pivotal trial evaluating zanzalintinib in combination with atezolizumab (Tecentriq®) versus regorafenib in previously treated non-microsatellite instability (MSI)-high metastatic colorectal cancer (mCRC).

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Key metrics vs top competitors for Exelixis, Inc. (EXEL)
| Company | Price | Market Cap | P/E Ratio | Rev Growth (1Y) | Net Margin | ROE | Div Yield |
|---|---|---|---|---|---|---|---|
| $57.08 | $14.5B | 20.53 | 6.98% | 33.73% | 35.53% | — | |
| $118.05 | $23.58B | 18.42 | 21.22% | 26.71% | 29.31% | — | |
| $55.22 | $9.2B | 38.62 | -5.25% | 9.78% | 8.82% | — | |
| $247.72 | $15.54B | -42.42 | 4.88% | 0.66% | 0.71% | — | |
| $86.33 | $14.27B | -36.27 | 33.87% | -30.87% | -58.57% | — | |
| $81.57 | $9.68B | 31.86 | 37.55% | 23.13% | 126.27% | — |
Exelixis, Inc. (EXEL) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
Exelixis, Inc. (EXEL) SEC filings — annual & quarterly reports (10-K, 10-Q)
May 5, 2026·SEC
Feb 10, 2026·SEC
Jan 12, 2026·SEC
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Exelixis, Inc. (EXEL) stock FAQ — growth, dividends, profitability & financials explained
Exelixis, Inc. (EXEL) reported $2.38B in revenue for fiscal year 2025. This represents a 22524% increase from $10.5M in 1999.
Exelixis, Inc. (EXEL) grew revenue by 7.0% over the past year. This is steady growth.
Yes, Exelixis, Inc. (EXEL) is profitable, generating $833.4M in net income for fiscal year 2025 (33.7% net margin).
Exelixis, Inc. (EXEL) has a return on equity (ROE) of 35.5%. This is excellent, indicating efficient use of shareholder capital.
Exelixis, Inc. (EXEL) generated $918.4M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.