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INCYIncyte Corporation
$118.05$23.6B
Overview & Verdict
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INCY logoIncyte Corporation(INCY)Earnings, Financials & Key Ratios

INCY•NASDAQ
$118.05
18.4× P/E·Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutIncyte Corporation, a biopharmaceutical company, focuses on the discovery, development, and commercialization of proprietary therapeutics in the United States and internationally. The company offers JAKAFI, a drug for the treatment of myelofibrosis and polycythemia vera; PEMAZYRE, a fibroblast growth factor receptor kinase inhibitor that act as oncogenic drivers in various liquid and solid tumor types; and ICLUSIG, a kinase inhibitor to treat chronic myeloid leukemia and philadelphia-chromosome positive acute lymphoblastic leukemia. Its clinical stage products include ruxolitinib, a steroid-refractory chronic graft-versus-host-diseases (GVHD); itacitinib, which is in Phase II/III clinical trial to treat naive chronic GVHD; and pemigatinib for treating bladder cancer, cholangiocarcinoma, myeloproliferative syndrome, and tumor agnostic. In addition, the company engages in developing Parsaclisib, which is in Phase II clinical trial for follicular lymphoma, marginal zone lymphoma, and mantel cell lymphoma. Additionally, it develops Retifanlimab that is in Phase II clinical trials for MSI-high endometrial cancer, merkel cell carcinoma, and anal cancer, as well as in Phase II clinical trials for patients with non-small cell lung cancer. It has collaboration agreements with Novartis International Pharmaceutical Ltd.; Eli Lilly and Company; Agenus Inc.; Calithera Biosciences, Inc; MacroGenics, Inc.; Merus N.V.; Syros Pharmaceuticals, Inc.; Innovent Biologics, Inc.; Zai Lab Limited; Cellenkos, Inc.; and Nimble Therapeutics, as well as clinical collaborations with MorphoSys AG and Xencor, Inc. to investigate the combination of tafasitamab, plamotamab, and lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma, and relapsed or refractory follicular lymphoma. The company was incorporated in 1991 and is headquartered in Wilmington, Delaware.Show more
  • Revenue$5.14B+21.2%
  • EBITDA$1.44B+747.8%
  • Net Income$1.29B+3845.0%
  • EPS (Diluted)6.41+4173.3%
  • Gross Margin91.47%+0.4%
  • EBITDA Margin27.93%+599.4%
  • Operating Margin26.12%+1282.2%
  • Net Margin25.03%+3154.4%
  • ROE29.87%+3855.2%

INCY Price & Volume

Incyte Corporation (INCY) stock price & volume — 10-year historical chart

Loading chart...

Dermatology Growth Offsets Impending Patent Cliff Risks

Investment Thesis • Updated 2026Q1

VerdictNeutral
Growth:Expanding
Profitability:Moderate
Financial:Fortress
Cash Flow:Mixed
Primary Risk:2028 Jakafi patent cliff

Key Thesis Takeaways

  • Incyte is successfully pivoting its revenue base toward the Opzelura dermatology franchise to mitigate the long-term impact of the 2028 Jakafi patent expiration.
  • While the company maintains a fortress balance sheet with $3.5 billion in cash, investors should monitor the volatility in operating margins, which fluctuated between 10% and 32% over the last ten quarters due to heavy R&D reinvestment.
  • The firm's ability to scale its non-oncology portfolio remains the critical determinant for sustaining its current 20.9% year-over-year revenue growth rate.

Verdict Logic

while the company exhibits a strong liquidity position with $3.5 billion in cash, the 2028 Jakafi patent cliff warrants caution as the firm attempts to scale its dermatology franchise to replace high-margin oncology earnings.

INCY Growth Metrics

Incyte Corporation (INCY) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years21.17%
5 Years14.03%
3 Years14.84%
TTM21.48%

Profit CAGR

10 Years69.61%
5 Years-
3 Years55.73%
TTM6631.44%

EPS CAGR

10 Years70.99%
5 Years-
3 Years61.56%
TTM2112.5%

Return on Capital

10 Years9.16%
5 Years15.08%
3 Years14.5%
Last Year29.05%

INCY Recent Earnings

Incyte Corporation (INCY) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)●Beat Revenue 7/12 qtrs (58%)
Q2 2026Latest
Apr 28, 2026
Metric
Actual
Est
EPS
$1.81+31.2%
$1.38
Rev
$1.3B+4.7%
$1.2B
Q1 2026
Feb 10, 2026
Metric
Actual
Est
EPS
$1.80-5.3%
$1.90
Rev
$1.5B+11.2%
$1.4B
Q4 2025
Oct 28, 2025
Metric
Actual
Est
EPS
$2.26+36.1%
$1.66
Rev
$1.4B+0.9%
$1.4B
Q3 2025
Jul 29, 2025
Metric
Actual
Est
EPS
$1.57+12.9%
$1.39
Rev
$1.2B-3.3%
$1.3B
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestApr 28, 2026
$1.81vs $1.38+31.2%
$1.3Bvs $1.2B+4.7%
Q1 2026Feb 10, 2026
$1.80vs $1.90-5.3%
$1.5Bvs $1.4B+11.2%
Q4 2025Oct 28, 2025
$2.26vs $1.66+36.1%
$1.4Bvs $1.4B+0.9%
Q3 2025Jul 29, 2025
$1.57vs $1.39+12.9%
$1.2Bvs $1.3B-3.3%
Based on last 12 quarters of dataView full earnings history →

Latest INCY News

Recent stock market news and headlines for Incyte Corporation (INCY)

Schaeffers Research·5 days ago
Dow Taps Record as Nasdaq, Chips Pull Back

Stocks are trading mixed as chip stocks weigh and investors digest a fresh batch of June nonfarm payrolls data

Zacks Investment Research·Jun 29, 2026
INCY Stock Hits 52-Week High on Regulatory Updates for Opzelura

Incyte shares hit a 52-week high as Opzelura gains regulatory momentum, pipeline advances and a CMS settlement boosts investor sentiment.

Zacks Investment Research·Jun 29, 2026
Incyte (INCY) Surges 5.8%: Is This an Indication of Further Gains?

Incyte (INCY) saw its shares surge in the last session with trading volume being higher than average. The latest trend in earnings estimate revisions may not translate into further price increase in the near term.

Seeking Alpha·Jun 29, 2026
Incyte: New Catalysts Support Another Leg Higher

Incyte Corporation remains a strong long pick, with a maintained 'Buy' rating and a 40% upside to a $159.5/share price target. Recent catalysts include a positive CHMP opinion for Opzelura in Europe and the acquisition of Vega Therapeutics, expanding INCY's product portfolio and reducing Jakafi concentration risk. Q1 2026 results showed robust diversification: revenues up 21% YoY, adjusted EPS up 56% YoY, and ex-Jakafi sales up 63% YoY.

GuruFocus·Jun 26, 2026
Incyte Announces Positive CHMP Opinion for Opzelura® (ruxolitinib) Cream for the Treatment of Adults with Moderate Atopic Dermatitis

Incyte (Nasdaq: INCY) today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has issued a positi

Peers Comparison

Key metrics vs top competitors for Incyte Corporation (INCY)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
INCY logoINCYIncyte CorporationCurrent
$118.05$23.58B18.4221.22%25.03%29.87%—
ALKS logoALKSAlkermes plc
$55.22$9.2B38.62-5.25%9.78%8.82%—
JAZZ logoJAZZJazz Pharmaceuticals plc
$247.72$15.54B-42.424.88%0.66%0.71%—
EXEL logoEXELExelixis, Inc.
$57.08$14.5B20.536.98%35.08%40.21%—
HALO logoHALOHalozyme Therapeutics, Inc.
$81.57$9.68B31.8637.55%23.13%126.27%—
IONS logoIONSIonis Pharmaceuticals, Inc.
$86.33$14.27B-36.2733.87%-30.87%-58.57%—

Compare INCY vs Peers

Incyte Corporation (INCY) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ALKS

Most directly comparable listed peer for INCY.

Scale Benchmark

vs LLY

Larger-name benchmark to compare INCY against a more recognizable public peer.

Peer Set

Compare Top 5

vs ALKS, JAZZ, EXEL, HALO

INCY SEC Filings & Documents

Incyte Corporation (INCY) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 28, 2026·SEC

Material company update

Mar 30, 2026·SEC

Material company update

Mar 26, 2026·SEC

10-K Annual Reports

2
FY 2026

Feb 10, 2026·SEC

FY 2025

Feb 10, 2025·SEC

10-Q Quarterly Reports

4
FY 2026

Apr 28, 2026·SEC

FY 2025

Oct 28, 2025·SEC

FY 2025

Jul 29, 2025·SEC

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INCY Frequently Asked Questions

Incyte Corporation (INCY) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Incyte Corporation's revenue?

Incyte Corporation (INCY) reported $5.36B in revenue for fiscal year 2025. This represents a 12725% increase from $41.8M in 1996.

How fast is Incyte Corporation growing?

Incyte Corporation (INCY) grew revenue by 21.2% over the past year. This is strong growth.

Is INCY profitable?

Yes, Incyte Corporation (INCY) is profitable, generating $1.43B in net income for fiscal year 2025 (25.0% net margin).

Dividend & Returns
What is INCY's return on equity?

Incyte Corporation (INCY) has a return on equity (ROE) of 29.9%. This is excellent, indicating efficient use of shareholder capital.

What is Incyte Corporation's free cash flow?

Incyte Corporation (INCY) generated $1.45B in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

What if you invested $1,000 in INCY back in 1996?

Total return calculator · dividends reinvested · 30+ years of data

See returns →