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SLXNSilexion Therapeutics Ltd.
$2.85$920655
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SLXN logoSilexion Therapeutics Ltd.(SLXN)Earnings, Financials & Key Ratios

SLXN•NASDAQ
$2.85
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryRNA and Genome Editing Developers
AboutSilexion Therapeutics LTD, a biopharmaceutical company, discovers and develops RNA interference (RNAi)-based cancer drugs and delivery systems to treat malignant solid tumors. The company engages in the treatment of solid tumors through its proprietary LODER delivery platform. Its products comprise SiG12D-LODER that has completed pre-clinical studies and an open label Phase I clinical trial for the treatment of pancreatic cancer; Prostate-LODER, which is in pre-clinical studies for the treatment of prostate cancer; and GBM-LODER that is in pre-clinical studies to target Glioblastoma Multiform, a malignant primary brain tumor. The company was founded in 2008 and is headquartered in Jerusalem, Israel.Show more
  • Revenue$0
  • EBITDA$12M+192.8%
  • Net Income-$12M+27.6%
  • EPS (Diluted)-89.60-239.4%
  • ROE-457.63%

SLXN Price & Volume

Silexion Therapeutics Ltd. (SLXN) stock price & volume — 10-year historical chart

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Clinical Development Costs Threaten Capital Liquidity Sustainability

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Imminent liquidity and dilution

Key Thesis Takeaways

  • Silexion Therapeutics faces a precarious financial outlook as it attempts to advance its LODER platform without a commercial revenue stream to offset significant R&D expenditures.
  • The company's reliance on external financing is evidenced by a rapid depletion of cash reserves and a shrinking equity base, which may necessitate further dilutive capital raises.
  • Investors should monitor the firm's ability to extend its limited cash runway, as the current burn rate of $2.7 million in quarterly losses poses a substantial risk to long-term solvency.

Verdict Logic

the company's precarious liquidity position, highlighted by a cash balance of only $2.4 million against quarterly losses of $2.7 million, suggests an imminent risk of significant shareholder dilution.

SLXN Growth Metrics

Silexion Therapeutics Ltd. (SLXN) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM23.18%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM403.07%

Return on Capital

10 Years-120.92%
5 Years-105.93%
3 Years-173.9%
Last Year612.69%

SLXN Recent Earnings

Silexion Therapeutics Ltd. (SLXN) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 2/8 qtrs (29%)
Q2 2026Latest
May 15, 2026
Metric
Actual
Est
EPS
$0.85+34.1%
$1.29
Rev
—
—
Q2 2026
Mar 17, 2026
Metric
Actual
Est
EPS
$2.38-103.8%
$1.17
Rev
—
—
Q4 2025
Nov 12, 2025
Metric
Actual
Est
EPS
$2.88+15.3%
$3.40
Rev
—
—
Q3 2025
Aug 12, 2025
Metric
Actual
Est
EPS
$4.32-37.1%
$3.15
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 15, 2026
$0.85vs $1.29+34.1%
—
Q2 2026Mar 17, 2026
$2.38vs $1.17-103.8%
—
Q4 2025Nov 12, 2025
$2.88vs $3.40+15.3%
—
Q3 2025Aug 12, 2025
$4.32vs $3.15-37.1%
—
Based on last 8 quarters of dataView full earnings history →

Latest SLXN News

Recent stock market news and headlines for Silexion Therapeutics Ltd. (SLXN)

GlobeNewsWire·Jun 23, 2026
Silexion Therapeutics Receives Approval from Germany's BfArM to Initiate Phase 2/3 Clinical Trial of SIL204 in Locally Advanced Pancreatic Cancer

CTA Approval from Germany's Federal Institute for Drugs and Medical Devices (BfArM), accompanied by a positive opinion from the Ethics Committee of the North Rhine Medical Association, clears Silexion to initiate the Phase 2/3 clinical trial of SIL204 in Germany

GlobeNewsWire·Jun 16, 2026
Silexion Therapeutics to Attend BIO International Convention 2026

Grand Cayman, June 16, 2026 (GLOBE NEWSWIRE) -- Silexion Therapeutics Corp. (“Silexion” or the “Company”), a clinical-stage biotechnology company pioneering RNA interference (RNAi) therapies for KRAS-driven cancers, today announced that Company management, including the Company's Chief Executive Officer, Ilan Hadar, and the Company's Chief Financial Officer, Mirit Horenshtein-Hadar, will attend the 2026 BIO International Convention, taking place on June 22-25 in San Diego, CA.  

Peers Comparison

Key metrics vs top competitors for Silexion Therapeutics Ltd. (SLXN)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
SLXN logoSLXNSilexion Therapeutics Ltd.Current
$2.85$920.65K-0.03——-457.63%—
SRPT logoSRPTSarepta Therapeutics, Inc.
$19.18$2.02B-2.6915.58%2.98%4.89%—
ARWR logoARWRArrowhead Pharmaceuticals, Inc.
$86.55$12.19B-7094.2623258.15%-48.38%-55.09%—
NTLA logoNTLAIntellia Therapeutics, Inc.
$17.84$2B-4.6816.92%-597.04%-57.27%—
IONS logoIONSIonis Pharmaceuticals, Inc.
$83.18$13.75B-34.9533.87%-30.87%-58.57%—
REGN logoREGNRegeneron Pharmaceuticals, Inc.
$649.81$67.52B15.670.99%29.65%14.32%—

Compare SLXN vs Peers

Silexion Therapeutics Ltd. (SLXN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs SRPT

Most directly comparable listed peer for SLXN.

Scale Benchmark

vs TMO

Larger-name benchmark to compare SLXN against a more recognizable public peer.

Peer Set

Compare Top 5

vs SRPT, ARWR, NTLA, IONS

SLXN SEC Filings & Documents

Silexion Therapeutics Ltd. (SLXN) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 18, 2026·SEC

Material company update

May 15, 2026·SEC

Material company update

May 14, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 17, 2026·SEC

FY 2025

Mar 18, 2025·SEC

10-Q Quarterly Reports

4
FY 2026

May 15, 2026·SEC

FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 12, 2025·SEC

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SLXN Frequently Asked Questions

Silexion Therapeutics Ltd. (SLXN) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is SLXN profitable?

Silexion Therapeutics Ltd. (SLXN) reported a net loss of $12.9M for fiscal year 2025.

Dividend & Returns
What is SLXN's return on equity?

Silexion Therapeutics Ltd. (SLXN) has a return on equity (ROE) of -457.6%. Negative ROE indicates the company is unprofitable.

What is Silexion Therapeutics Ltd.'s free cash flow?

Silexion Therapeutics Ltd. (SLXN) had negative free cash flow of $12.0M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in SLXN back in 2020?

Total return calculator · dividends reinvested · 6+ years of data

See returns →