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HALOHalozyme Therapeutics, Inc.
$81.57$9.7B
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HALO logoHalozyme Therapeutics, Inc.(HALO)Earnings, Financials & Key Ratios

HALO•NASDAQ
$81.57
31.9× P/E·Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryDrug Delivery Technology Platforms
AboutHalozyme Therapeutics, Inc. operates as a biopharma technology platform company in the United States, Switzerland, Ireland, Belgium, Japan, and internationally. The company's products are based on the ENHANZE drug delivery technology, a patented recombinant human hyaluronidase enzyme (rHuPH20) that enables the subcutaneous delivery of injectable biologics, such as monoclonal antibodies and other therapeutic molecules, as well as small molecules and fluids. Its flagship product is Hylenex recombinant, a formulation of rHuPH20 to facilitate subcutaneous fluid administration for achieving hydration to enhance the dispersion and absorption of other injected drugs in subcutaneous urography and to improve resorption of radiopaque agents. The company also develops Perjeta; RITUXAN HYCELA and MabThera SC for the treatment of non-Hodgkin lymphoma and chronic lymphocytic leukemia (CLL); RITUXAN SC for patients with CLL; and HYQVIA for the treatment of immunodeficiency disorders. In addition, it is developing Tecentriq for non-small cell lung cancer; OCREVUS for multiple sclerosis; DARZALEX for the treatment of patients with amyloidosis, smoldering myeloma, and multiple myeloma; nivolumab for the treatment of solid tumors; ARGX-113, a human neonatal Fc receptor; ARGX-117 to treat autoimmune diseases; and BMS-986179, an anti-CD-73 antibody. The company has collaborations with F. Hoffmann-La Roche, Ltd.; Hoffmann-La Roche, Inc.; Baxalta US Inc.; Baxalta GmbH; Pfizer Inc.; Janssen Biotech, Inc.; AbbVie, Inc.; Eli Lilly and Company; Bristol-Myers Squibb Company; Alexion Pharma Holding; ARGENX BVBA; Horizon Therapeutics plc; National Institute of Allergy and Infectious Diseases; Centre for the AIDS Programme of Research in South Africa; and ViiV Healthcare Limited for small and large molecule targets for the treatment and prevention of HIV. Halozyme Therapeutics, Inc. was founded in 1998 and is based in San Diego, California.Show more
  • Revenue$1.4B+37.6%
  • EBITDA$904M+42.9%
  • Net Income$317M-28.6%
  • EPS (Diluted)2.56-25.4%
  • Gross Margin78.13%-7.3%
  • EBITDA Margin64.75%+3.9%
  • Operating Margin58.45%+7.6%
  • Net Margin22.69%-48.1%
  • ROE153.59%-22.6%

HALO Price & Volume

Halozyme Therapeutics, Inc. (HALO) stock price & volume — 10-year historical chart

Loading chart...

Scalable Royalty Model Drives Robust Margin Expansion

Investment Thesis • Updated 2026Q1

VerdictNeutral
Growth:Expanding
Profitability:Strong
Financial:Mixed
Cash Flow:Robust
Primary Risk:Royalty concentration and leverage

Key Thesis Takeaways

  • Halozyme Therapeutics leverages its high-margin ENHANZE platform to drive significant revenue growth, evidenced by a 42.2% year-over-year increase in 2026Q1.
  • While the company demonstrates strong operational leverage and cash generation, investors should monitor the risks associated with a highly leveraged capital structure, characterized by a 9.76 debt-to-equity ratio.
  • Future performance remains contingent on the successful navigation of royalty concentration and potential patent cliffs affecting its core partner biologics.

Verdict Logic

while the forward P/E of 9.24 suggests potential undervaluation, the elevated debt-to-equity ratio of 9.76 and reliance on milestone-driven cash flows warrant a cautious approach to long-term capital appreciation.

HALO Growth Metrics

Halozyme Therapeutics, Inc. (HALO) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years26.32%
5 Years39.16%
3 Years28.38%
TTM39.12%

Profit CAGR

10 Years-
5 Years19.68%
3 Years16.17%
TTM-28.13%

EPS CAGR

10 Years-
5 Years22.98%
3 Years21.14%
TTM-26.06%

Return on Capital

10 Years14.1%
5 Years31.52%
3 Years29.86%
Last Year38.21%

HALO Recent Earnings

Halozyme Therapeutics, Inc. (HALO) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 10/12 qtrs (83%)●Beat Revenue 5/12 qtrs (42%)
Q2 2026Latest
May 11, 2026
Metric
Actual
Est
EPS
$1.60+3.2%
$1.55
Rev
$377M+5.0%
$359M
Q1 2026
Feb 17, 2026
Metric
Actual
Est
EPS
$0.24-111.2%
$2.15
Rev
$452M+3.7%
$436M
Q4 2025
Nov 3, 2025
Metric
Actual
Est
EPS
$1.72+5.5%
$1.63
Rev
$354M-20.7%
$447M
Q3 2025
Aug 5, 2025
Metric
Actual
Est
EPS
$1.54+25.2%
$1.23
Rev
$326M-1.5%
$331M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 11, 2026
$1.60vs $1.55+3.2%
$377Mvs $359M+5.0%
Q1 2026Feb 17, 2026
$0.24vs $2.15-111.2%
$452Mvs $436M+3.7%
Q4 2025Nov 3, 2025
$1.72vs $1.63+5.5%
$354Mvs $447M-20.7%
Q3 2025Aug 5, 2025
$1.54vs $1.23+25.2%
$326Mvs $331M-1.5%
Based on last 12 quarters of dataView full earnings history →

Latest HALO News

Recent stock market news and headlines for Halozyme Therapeutics, Inc. (HALO)

PRNewsWire·Jun 30, 2026
Halozyme Appoints David Ramsay as President Drug Delivery

SAN DIEGO, June 30, 2026 /PRNewswire/ -- Halozyme Therapeutics, Inc. (Nasdaq: HALO) ("Halozyme" or the "Company") today announced the appointment of David Ramsay as President Drug Delivery, effective June 30, 2026. In this newly created role, Mr.

Peers Comparison

Key metrics vs top competitors for Halozyme Therapeutics, Inc. (HALO)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
HALO logoHALOHalozyme Therapeutics, Inc.Current
$81.57$9.68B31.8637.55%22.69%153.59%—
ALNY logoALNYAlnylam Pharmaceuticals, Inc.
$321.59$42.91B138.0265.19%13.46%98.29%—
IONS logoIONSIonis Pharmaceuticals, Inc.
$86.33$14.27B-36.2733.87%-30.87%-58.57%—
ARWR logoARWRArrowhead Pharmaceuticals, Inc.
$86.97$12.25B-7128.6923258.15%-48.38%-55.09%—
EXEL logoEXELExelixis, Inc.
$57.08$14.5B20.536.98%35.08%40.21%—
INVA logoINVAInnoviva, Inc.
$22.25$1.64B6.7418.52%118.91%47.59%—

Compare HALO vs Peers

Halozyme Therapeutics, Inc. (HALO) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ALNY

Most directly comparable listed peer for HALO.

Scale Benchmark

vs JNJ

Larger-name benchmark to compare HALO against a more recognizable public peer.

Peer Set

Compare Top 5

vs ALNY, IONS, ARWR, EXEL

HALO SEC Filings & Documents

Halozyme Therapeutics, Inc. (HALO) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 11, 2026·SEC

Material company update

May 7, 2026·SEC

Material company update

Apr 30, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 17, 2026·SEC

FY 2025

Feb 18, 2025·SEC

FY 2024

Feb 20, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 11, 2026·SEC

FY 2025

Nov 3, 2025·SEC

FY 2025

Aug 5, 2025·SEC

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HALO Frequently Asked Questions

Halozyme Therapeutics, Inc. (HALO) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Halozyme Therapeutics, Inc.'s revenue?

Halozyme Therapeutics, Inc. (HALO) reported $1.51B in revenue for fiscal year 2025. This represents a 6110728% increase from $0.0M in 2001.

How fast is Halozyme Therapeutics, Inc. growing?

Halozyme Therapeutics, Inc. (HALO) grew revenue by 37.6% over the past year. This is strong growth.

Is HALO profitable?

Yes, Halozyme Therapeutics, Inc. (HALO) is profitable, generating $348.8M in net income for fiscal year 2025 (22.7% net margin).

Dividend & Returns
What is HALO's return on equity?

Halozyme Therapeutics, Inc. (HALO) has a return on equity (ROE) of 153.6%. This is excellent, indicating efficient use of shareholder capital.

What is Halozyme Therapeutics, Inc.'s free cash flow?

Halozyme Therapeutics, Inc. (HALO) generated $667.7M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

What if you invested $1,000 in HALO back in 2001?

Total return calculator · dividends reinvested · 25+ years of data

See returns →