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UNCYUnicycive Therapeutics, Inc.
$5.36$1.3B
Overview & Verdict
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UNCY logoUnicycive Therapeutics, Inc.(UNCY)Earnings, Financials & Key Ratios

UNCY•NASDAQ
$5.36
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Specialty Pharma
AboutUnicycive Therapeutics, Inc., a biotechnology company, engages in developing novel therapies for kidney diseases in the United States. It is developing Renazorb for treatment of hyperphosphatemia in patients with chronic kidney disease; and UNI 494, for treatment of acute kidney injury. The company was incorporated in 2016 and is based in Los Altos, California.Show more
  • Revenue$0
  • EBITDA-$29M+8.7%
  • Net Income-$27M+27.7%
  • EPS (Diluted)-1.67+70.2%
  • ROE-141.14%+93.0%

UNCY Price & Volume

Unicycive Therapeutics, Inc. (UNCY) stock price & volume — 10-year historical chart

Loading chart...

Persistent Operating Losses Challenge Clinical Development Runway

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Binary Regulatory Funding Risk

Key Thesis Takeaways

  • Unicycive Therapeutics remains a high-risk, pre-revenue biotechnology firm whose valuation is entirely contingent upon the successful regulatory navigation of its lead candidate, Renazorb.
  • While the 505(b)(2) pathway offers a potential shortcut to market, the company's lack of commercial infrastructure and consistent quarterly operating losses averaging $7.5 million suggest significant execution hurdles ahead.
  • Investors should monitor the company's ability to manage its $140.6 million accumulated deficit against a tightening cash position of $37.4 million as of 2026Q1.

Verdict Logic

the company's reliance on external capital to fund a $7.5 million average quarterly operating loss, combined with a lack of commercial revenue, presents a binary regulatory risk that outweighs current valuation multiples.

UNCY Growth Metrics

Unicycive Therapeutics, Inc. (UNCY) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-162.89%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM45.05%

Return on Capital

10 Years-508.93%
5 Years-508.93%
3 Years-841.98%
Last Year-156.4%

UNCY Recent Earnings

Unicycive Therapeutics, Inc. (UNCY) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 7/12 qtrs (58%)
Q2 2026Latest
May 12, 2026
Metric
Actual
Est
EPS
$0.54-17.7%
$0.46
Rev
—
$11M
Q2 2026
Mar 30, 2026
Metric
Actual
Est
EPS
$0.32+36.6%
$0.50
Rev
—
$517,000
Q4 2025
Nov 12, 2025
Metric
Actual
Est
EPS
$0.39+33.9%
$0.59
Rev
—
—
Q3 2025
Aug 14, 2025
Metric
Actual
Est
EPS
$0.52+25.7%
$0.70
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 12, 2026
$0.54vs $0.46-17.7%
—vs $11M
Q2 2026Mar 30, 2026
$0.32vs $0.50+36.6%
—vs $517,000
Q4 2025Nov 12, 2025
$0.39vs $0.59+33.9%
—
Q3 2025Aug 14, 2025
$0.52vs $0.70+25.7%
—
Based on last 12 quarters of dataView full earnings history →

Latest UNCY News

Recent stock market news and headlines for Unicycive Therapeutics, Inc. (UNCY)

GlobeNewsWire·4 days ago
Bragar Eagel & Squire, P.C. is Investigating Unicycive Therapeutics, Inc. on Behalf of Unicycive Stockholders and Encourages Investors to Contact the Firm

Bragar Eagel & Squire, P.C.  Litigation Partner  Brandon Walker  Encourages Investors Who Suffered Losses In Unicycive (UNCY) To Contact Him Directly To Discuss Their Options

GlobeNewsWire·6 days ago
Johnson Fistel Investigates Unicycive Therapeutics, Inc. (NASDAQ: UNCY) on Behalf of Investors

SAN DIEGO, June 30, 2026 (GLOBE NEWSWIRE) -- Johnson Fistel, PLLP is investigating Unicycive Therapeutics, Inc. (NASDAQ: UNCY) on behalf of investors who suffered losses and whether those losses may be recoverable under federal securities laws.

Peers Comparison

Key metrics vs top competitors for Unicycive Therapeutics, Inc. (UNCY)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
UNCY logoUNCYUnicycive Therapeutics, Inc.Current
$5.36$1.28B-3.21——-141.14%—
ARWR logoARWRArrowhead Pharmaceuticals, Inc.
$86.55$12.19B-7094.2623258.15%-48.38%-55.09%—
CYCN logoCYCNCyclerion Therapeutics, Inc.
$3.46$14.98M-3.173.7%-264.73%-62.1%—
RMTI logoRMTIRockwell Medical, Inc.
$5.60$22.1M-3.73-31.76%-7.98%-15.41%—
LPCN logoLPCNLipocine Inc.
$2.47$13.45M-1.46-82.35%-571.1%-66.69%—
NKTR logoNKTRNektar Therapeutics
$73.15$1.43B-7.52-43.89%-284.18%-87%—

Compare UNCY vs Peers

Unicycive Therapeutics, Inc. (UNCY) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ARWR

Most directly comparable listed peer for UNCY.

Scale Benchmark

vs RVMD

Larger-name benchmark to compare UNCY against a more recognizable public peer.

Peer Set

Compare Top 5

vs ARWR, CYCN, RMTI, LPCN

UNCY SEC Filings & Documents

Unicycive Therapeutics, Inc. (UNCY) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 12, 2026·SEC

Material company update

Apr 6, 2026·SEC

Material company update

Mar 30, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 30, 2026·SEC

FY 2025

Mar 31, 2025·SEC

FY 2024

Mar 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 12, 2026·SEC

FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 14, 2025·SEC

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UNCY Frequently Asked Questions

Unicycive Therapeutics, Inc. (UNCY) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is UNCY profitable?

Unicycive Therapeutics, Inc. (UNCY) reported a net loss of $39.9M for fiscal year 2025.

Dividend & Returns
What is UNCY's return on equity?

Unicycive Therapeutics, Inc. (UNCY) has a return on equity (ROE) of -141.1%. Negative ROE indicates the company is unprofitable.

What is Unicycive Therapeutics, Inc.'s free cash flow?

Unicycive Therapeutics, Inc. (UNCY) had negative free cash flow of $28.7M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in UNCY back in 2018?

Total return calculator · dividends reinvested · 8+ years of data

See returns →