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SAVACassava Sciences, Inc.
$1.32$64M
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SAVA logoCassava Sciences, Inc.(SAVA)Earnings, Financials & Key Ratios

SAVA•NASDAQ
$1.32
Price updated Jun 20, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutCassava Sciences, Inc., a clinical stage biotechnology company, develops drugs for neurodegenerative diseases. Its lead therapeutic product candidate is simufilam, a small molecule drug, which is completed Phase 2b clinical trial; and investigational diagnostic product candidate is SavaDx, a blood-based biomarker/diagnostic to detect Alzheimer's disease. The company was formerly known as Pain Therapeutics, Inc. and changed its name to Cassava Sciences, Inc. in March 2019. Cassava Sciences, Inc. was incorporated in 1998 and is based in Austin, Texas.Show more
  • Revenue$0
  • EBITDA-$140M-34.4%
  • Net Income-$24M+75.0%
  • EPS (Diluted)-0.52+77.6%
  • ROE-17.19%+67.7%

SAVA Price & Volume

Cassava Sciences, Inc. (SAVA) stock price & volume — 10-year historical chart

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Persistent Cash Burn Challenges Clinical Development Outlook

Investment Thesis • Updated 2025Q3

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical trial binary outcome

Key Thesis Takeaways

  • Cassava Sciences remains a high-risk, pre-revenue biotechnology firm entirely dependent on the successful clinical validation of its lead candidate, Simufilam.
  • The company faces significant financial pressure as it navigates late-stage trials, evidenced by a cumulative retained earnings deficit of -$483.5 million and ongoing operational losses.
  • Investors must weigh the binary outcome of clinical milestones against the firm's narrowing liquidity buffer and the potential for future dilutive capital raises to sustain operations.

Verdict Logic

the firm's reliance on external financing is underscored by a 2025Q3 net loss of $10.8 million and a lack of revenue-generating activities, creating substantial risk for equity holders.

SAVA Growth Metrics

Cassava Sciences, Inc. (SAVA) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-500.27%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-58.7%

Return on Capital

10 Years-47.81%
5 Years-44.26%
3 Years-63.7%
Last Year-99.87%

SAVA Recent Earnings

Cassava Sciences, Inc. (SAVA) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (50%)
Q4 2025Latest
Nov 12, 2025
Metric
Actual
Est
EPS
$0.22+18.5%
$0.27
Rev
—
—
Q3 2025
Aug 14, 2025
Metric
Actual
Est
EPS
$0.18
—
Rev
—
—
Q2 2025
May 8, 2025
Metric
Actual
Est
EPS
$0.48
—
Rev
—
—
Q2 2025
Mar 3, 2025
Metric
Actual
Est
EPS
$0.57+16.2%
$0.68
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q4 2025LatestNov 12, 2025
$0.22vs $0.27+18.5%
—
Q3 2025Aug 14, 2025
$0.18
—
Q2 2025May 8, 2025
$0.48
—
Q2 2025Mar 3, 2025
$0.57vs $0.68+16.2%
—
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Cassava Sciences, Inc. (SAVA)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
SAVA logoSAVACassava Sciences, Inc.Current
$1.32$63.77M-2.54——-17.19%—
ACAD logoACADACADIA Pharmaceuticals Inc.
$26.20$4.49B11.4411.87%34.3%35.65%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$323.95$9.36B-24.03-100%—-43.02%—
ATNM logoATNMActinium Pharmaceuticals, Inc.
$1.03$32.32M-0.95—-26078.89%-218.67%—
AVXL logoAVXLAnavex Life Sciences Corp.
$2.71$251.14M-5.02——-38.76%—
ACIU logoACIUAC Immune S.A.
$2.54$258.5M-2.93-86.92%-1971.7%-101.76%—

Compare SAVA vs Peers

Cassava Sciences, Inc. (SAVA) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ACAD

Most directly comparable listed peer for SAVA.

Scale Benchmark

vs LLY

Larger-name benchmark to compare SAVA against a more recognizable public peer.

Peer Set

Compare Top 5

vs ACAD, PRAX, ATNM, AVXL

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SAVA Frequently Asked Questions

Cassava Sciences, Inc. (SAVA) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is SAVA profitable?

Cassava Sciences, Inc. (SAVA) reported a net loss of $106.0M for fiscal year 2024.

Dividend & Returns
What is SAVA's return on equity?

Cassava Sciences, Inc. (SAVA) has a return on equity (ROE) of -17.2%. Negative ROE indicates the company is unprofitable.

What is Cassava Sciences, Inc.'s free cash flow?

Cassava Sciences, Inc. (SAVA) had negative free cash flow of $83.9M in fiscal year 2024, likely due to heavy capital investments.

What if you invested $1,000 in SAVA back in 1999?

Total return calculator · dividends reinvested · 27+ years of data

See returns →