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AVXLAnavex Life Sciences Corp.
$2.71$251M
Overview & Verdict
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AVXL logoAnavex Life Sciences Corp.(AVXL)Earnings, Financials & Key Ratios

AVXL•NASDAQ
$2.71
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutAnavex Life Sciences Corp., a clinical stage biopharmaceutical company, engages in the development of drug candidates for the treatment of central nervous system (CNS) diseases. Its lead drug candidate is ANAVEX 2-73, which is in Phase III clinical trial for the treatment of Alzheimer's disease; Phase III clinical trial to treat pediatric patients with Rett syndrome; Phase II clinical trial for the treatment of Parkinson's disease; and preclinical clinical trials to treat epilepsy, infantile spasms, Fragile X syndrome, Angelman syndrome, multiple sclerosis, and tuberous sclerosis complex. The company's drug candidate also comprises ANAVEX 3-71, which is in Phase I clinical trial for the treatment of frontotemporal dementia and other dementia indications; and preclinical clinical trials for the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases. Its preclinical drug candidates include ANAVEX 1-41, a sigma-1 receptor agonist for the treatment of depression, stroke, Parkinson's, and Alzheimer's diseases; ANAVEX 1066, a mixed sigma-1/sigma-2 ligand for the potential treatment of neuropathic and visceral pain; and ANAVEX 1037 to treat prostate and pancreatic cancer. The company was incorporated in 2004 and is headquartered in New York, New York.Show more
  • Revenue$0
  • EBITDA-$46M-7.8%
  • Net Income-$46M-7.8%
  • EPS (Diluted)-0.54-3.8%
  • ROE-43.11%-31.4%

AVXL Price & Volume

Anavex Life Sciences Corp. (AVXL) stock price & volume — 10-year historical chart

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Persistent R&D Burn Challenges Clinical Development Runway

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Binary Clinical Trial Outcomes

Key Thesis Takeaways

  • Anavex Life Sciences remains a pre-revenue biotechnology firm entirely dependent on external financing to fund its late-stage CNS pipeline, as evidenced by cumulative retained earnings losses of $388.1 million.
  • While the company maintains a debt-free balance sheet, the consistent quarterly R&D expenditure—peaking at $11.8 million—creates significant binary risk regarding future regulatory approvals.
  • Investors should monitor the company's ability to manage its $131.7 million cash position against ongoing operational losses before further dilutive equity issuance becomes necessary.

Verdict Logic

the company's reliance on equity-linked financing to cover quarterly R&D costs of up to $11.8 million presents substantial dilution risk to shareholders in the absence of commercial revenue.

AVXL Growth Metrics

Anavex Life Sciences Corp. (AVXL) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM14.08%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM15.67%

Return on Capital

10 Years-41.86%
5 Years-41.86%
3 Years-42.45%
Last Year-47.79%

AVXL Recent Earnings

Anavex Life Sciences Corp. (AVXL) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)
Q3 2026Latest
Jun 30, 2026
Metric
Actual
Est
EPS
$0.07+0.0%
$0.07
Rev
—
—
Q3 2026
Jun 23, 2026
Metric
Actual
Est
EPS
$0.07+0.0%
$0.07
Rev
—
—
Q3 2026
Jun 16, 2026
Metric
Actual
Est
EPS
$0.07+0.0%
$0.07
Rev
—
—
Q3 2026
Jun 9, 2026
Metric
Actual
Est
EPS
$0.07+0.0%
$0.07
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026LatestJun 30, 2026
$0.07vs $0.07+0.0%
—
Q3 2026Jun 23, 2026
$0.07vs $0.07+0.0%
—
Q3 2026Jun 16, 2026
$0.07vs $0.07+0.0%
—
Q3 2026Jun 9, 2026
$0.07vs $0.07+0.0%
—
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Anavex Life Sciences Corp. (AVXL)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
AVXL logoAVXLAnavex Life Sciences Corp.Current
$2.71$251.14M-5.02——-43.11%—
SAVA logoSAVACassava Sciences, Inc.
$1.32$63.77M-2.54——-95.77%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$323.95$9.36B-24.03-100%—-43.02%—
ACAD logoACADACADIA Pharmaceuticals Inc.
$26.20$4.49B11.4411.87%34.3%35.65%—
ATNM logoATNMActinium Pharmaceuticals, Inc.
$1.03$32.32M-0.95—-26078.89%-218.67%—
BIIB logoBIIBBiogen Inc.
$205.70$30.37B23.301.39%13.92%7.55%—

Compare AVXL vs Peers

Anavex Life Sciences Corp. (AVXL) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs SAVA

Most directly comparable listed peer for AVXL.

Scale Benchmark

vs LLY

Larger-name benchmark to compare AVXL against a more recognizable public peer.

Peer Set

Compare Top 5

vs SAVA, PRAX, ACAD, ATNM

AVXL SEC Filings & Documents

Anavex Life Sciences Corp. (AVXL) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jun 26, 2026·SEC

Material company update

May 22, 2026·SEC

Material company update

May 15, 2026·SEC

10-K Annual Reports

5
FY 2025

Nov 25, 2025·SEC

FY 2024

Dec 23, 2024·SEC

FY 2023

Nov 27, 2023·SEC

10-Q Quarterly Reports

6
FY 2026

Feb 9, 2026·SEC

FY 2025

Aug 12, 2025·SEC

FY 2025

May 13, 2025·SEC

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AVXL Frequently Asked Questions

Anavex Life Sciences Corp. (AVXL) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is AVXL profitable?

Anavex Life Sciences Corp. (AVXL) reported a net loss of $39.9M for fiscal year 2025.

Dividend & Returns
What is AVXL's return on equity?

Anavex Life Sciences Corp. (AVXL) has a return on equity (ROE) of -43.1%. Negative ROE indicates the company is unprofitable.

What is Anavex Life Sciences Corp.'s free cash flow?

Anavex Life Sciences Corp. (AVXL) had negative free cash flow of $34.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in AVXL back in 2004?

Total return calculator · dividends reinvested · 22+ years of data

See returns →