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QUREuniQure N.V.
$41.41$2.6B
Overview & Verdict
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QURE logouniQure N.V.(QURE)Earnings, Financials & Key Ratios

QURE•NASDAQ
$41.41
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCell and Gene Therapy Developers
AboutuniQure N.V., a gene therapy company, engages in the development of treatments for patients suffering from genetic and other devastating diseases. Its lead program is Etranacogene dezaparvovec (AMT-061), which is in Phase III HOPE-B pivotal trial for the treatment of hemophilia B. The company also engages in developing AMT-130, a gene therapy that is in Phase I/II clinical study for the treatment of Huntington's disease; AMT-060, which is in Phase I/II clinical trial for the treatment of hemophilia B; AMT-210, a product candidate for the treatment of Parkinson's disease; AMT-260 for temporal lobe epilepsy; AMT-240, a preclinical product candidate for the treatment of autosomal dominant Alzheimer's disease; and AMT-161 for the treatment of amyotrophic lateral sclerosis. uniQure N.V. was founded in 1998 and is headquartered in Amsterdam, the Netherlands.Show more
  • Revenue$16M-40.6%
  • EBITDA-$173M-0.8%
  • Net Income-$199M+16.9%
  • EPS (Diluted)-3.46+29.7%
  • Gross Margin89.53%+176.1%
  • EBITDA Margin-1075.09%-69.9%
  • Operating Margin-1166.77%-71.7%
  • Net Margin-1236%-39.9%
  • ROE-207.1%+13.2%

QURE Price & Volume

uniQure N.V. (QURE) stock price & volume — 10-year historical chart

Loading chart...

Clinical Pipeline Volatility Masks Structural Liquidity Risks

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical trial binary outcomes

Key Thesis Takeaways

  • uniQure's financial profile is defined by extreme revenue volatility tied to milestone payments, which obscures the underlying sustainability of its gene therapy business model.
  • While the company maintains a specialized R&D infrastructure, the persistent quarterly net losses often exceeding $50 million necessitate ongoing external capital reliance.
  • Investors should monitor the clinical progression of AMT-130, as the firm's long-term viability remains tethered to binary trial outcomes rather than predictable commercial cash flows.

Verdict Logic

the company's cash position has declined from $241.4 million in 2023Q4 to $140.0 million in 2026Q1, signaling significant long-term solvency risks absent a successful commercial breakthrough.

QURE Growth Metrics

uniQure N.V. (QURE) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years4.56%
5 Years-15.57%
3 Years-46.73%
TTM-10.44%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM4%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM20.05%

Return on Capital

10 Years-24.83%
5 Years-12.46%
3 Years-33.03%
Last Year-29.38%

QURE Recent Earnings

uniQure N.V. (QURE) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 7/12 qtrs (58%)●Beat Revenue 5/12 qtrs (42%)
Q2 2026Latest
May 5, 2026
Metric
Actual
Est
EPS
$0.85+3.4%
$0.88
Rev
$4M-31.6%
$5M
Q2 2026
Mar 2, 2026
Metric
Actual
Est
EPS
$0.56+39.8%
$0.93
Rev
$6M+4.5%
$5M
Q4 2025
Nov 10, 2025
Metric
Actual
Est
EPS
$1.38-62.4%
$0.85
Rev
$4M-23.6%
$5M
Q3 2025
Jul 29, 2025
Metric
Actual
Est
EPS
$0.69+22.5%
$0.89
Rev
$5M+13.7%
$5M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 5, 2026
$0.85vs $0.88+3.4%
$4Mvs $5M-31.6%
Q2 2026Mar 2, 2026
$0.56vs $0.93+39.8%
$6Mvs $5M+4.5%
Q4 2025Nov 10, 2025
$1.38vs $0.85-62.4%
$4Mvs $5M-23.6%
Q3 2025Jul 29, 2025
$0.69vs $0.89+22.5%
$5Mvs $5M+13.7%
Based on last 12 quarters of dataView full earnings history →

Latest QURE News

Recent stock market news and headlines for uniQure N.V. (QURE)

Zacks Investment Research·6 days ago
uniQure (QURE) Now Trades Above Golden Cross: Time to Buy?

uniQure N.V. (QURE) reached a significant support level, and could be a good pick for investors from a technical perspective.

GlobeNewsWire·Jun 25, 2026
uniQure Announces Closing of Upsized Public Offering and Full Exercise by Underwriters of Option to Purchase Additional Shares

LEXINGTON, Mass. and AMSTERDAM, June 25, 2026 (GLOBE NEWSWIRE) -- uniQure N.V. (Nasdaq: QURE), a leading gene therapy company advancing transformative therapies for patients with severe medical needs, today announced the closing of its previously announced underwritten public offering of 5,686,813 ordinary shares at a public offering price of $45.50 per share, which includes 741,758 ordinary shares issued pursuant to the exercise in full by the underwriters of their option to purchase additional ordinary shares in the offering. The aggregate gross proceeds to uniQure from the offering, before deducting the underwriting discounts and commissions and offering expenses payable by uniQure, were approximately $259 million. All securities in the offering were sold by uniQure.

GlobeNewsWire·Jun 23, 2026
uniQure Announces Pricing of Upsized $225 Million Public Offering

LEXINGTON, Mass. and AMSTERDAM, June 23, 2026 (GLOBE NEWSWIRE) -- uniQure N.V. (Nasdaq: QURE), a leading gene therapy company advancing transformative therapies for patients with severe medical needs, today announced the pricing of its previously announced underwritten public offering of 4,945,055 ordinary shares at a public offering price of $45.50 per share. The aggregate gross proceeds to uniQure from the offering, before deducting the underwriting discounts and commissions and offering expenses payable by uniQure, are expected to be approximately $225 million. All securities to be sold in the offering are being sold by uniQure. In addition, uniQure has granted to the underwriters a 30-day option to purchase up to 741,758 additional ordinary shares at the public offering price, less underwriting discounts and commissions. The offering is expected to close on or about June 25, 2026, subject to the satisfaction of customary closing conditions.

GlobeNewsWire·Jun 22, 2026
uniQure Announces $150 Million Proposed Public Offering

LEXINGTON, Mass. and AMSTERDAM, June 22, 2026 (GLOBE NEWSWIRE) -- uniQure N.V. (Nasdaq: QURE), a leading gene therapy company advancing transformative therapies for patients with severe medical needs, today announced that it has commenced a $150 million underwritten public offering of its ordinary shares and, in lieu of ordinary shares to certain investors, pre-funded warrants to purchase its ordinary shares. All securities to be sold in the offering will be offered by uniQure. In addition, uniQure intends to grant the underwriters a 30-day option to purchase up to an additional $22.5 million of its ordinary shares on the same terms and conditions. The offering is subject to market and other conditions, and there can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering.

Zacks Investment Research·Jun 22, 2026
QURE Announces Initial Data on Gene therapy for Temporal Lobe Epilepsy

uniQure reports early AMT-260 epilepsy study data, with three patients showing 79-100% seizure reductions and no serious safety events.

Peers Comparison

Key metrics vs top competitors for uniQure N.V. (QURE)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
QURE logoQUREuniQure N.V.Current
$41.41$2.59B-11.97-40.64%-1236%-207.1%—
SRPT logoSRPTSarepta Therapeutics, Inc.
$19.79$2.09B-2.7815.58%2.98%4.89%—
BMRN logoBMRNBioMarin Pharmaceutical Inc.
$60.35$11.61B33.5312.87%8.29%4.41%—
CRSP logoCRSPCRISPR Therapeutics AG
$60.77$5.86B-9.39-89.97%-13856.54%-30.88%—
EDIT logoEDITEditas Medicine, Inc.
$3.75$367.15M-2.0825.39%-281.59%-677.39%—
NTLA logoNTLAIntellia Therapeutics, Inc.
$17.43$1.96B-4.5716.92%-597.04%-57.27%—

Compare QURE vs Peers

uniQure N.V. (QURE) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs SRPT

Most directly comparable listed peer for QURE.

Scale Benchmark

vs REGN

Larger-name benchmark to compare QURE against a more recognizable public peer.

Peer Set

Compare Top 5

vs SRPT, BMRN, CRSP, EDIT

QURE SEC Filings & Documents

uniQure N.V. (QURE) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 5, 2026·SEC

Material company update

Apr 30, 2026·SEC

Material company update

Mar 2, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 2, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 5, 2026·SEC

FY 2025

Nov 10, 2025·SEC

FY 2025

Jul 29, 2025·SEC

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QURE Frequently Asked Questions

uniQure N.V. (QURE) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is uniQure N.V.'s revenue?

uniQure N.V. (QURE) reported $18.1M in revenue for fiscal year 2025.

How fast is uniQure N.V. growing?

uniQure N.V. (QURE) saw revenue decline by 40.6% over the past year.

Is QURE profitable?

uniQure N.V. (QURE) reported a net loss of $208.9M for fiscal year 2025.

Dividend & Returns
What is QURE's return on equity?

uniQure N.V. (QURE) has a return on equity (ROE) of -207.1%. Negative ROE indicates the company is unprofitable.

What is uniQure N.V.'s free cash flow?

uniQure N.V. (QURE) had negative free cash flow of $172.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in QURE back in 2011?

Total return calculator · dividends reinvested · 15+ years of data

See returns →