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PLSEPulse Biosciences, Inc.
$28.03$1.9B
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  4. Financial Ratios

Pulse Biosciences, Inc. (PLSE) Financial Ratios

Latest Ratios: P/E Ratio -26.0x · EV/EBITDA N/A · ROE -74.4%. (2014–2025 historical series)

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly

PLSE Valuation Multiples

Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Market Cap$1.9B$925M$1.0B$588M$94M$414M$555M$278M$196M$348M$72M
Enterprise Value$1.9B$852M$908M$553M$109M$397M$554M$278M$145M$345M$69M
P/E Ratio →-25.95——————————
P/S Ratio5542.712643.82——134.29292.06—————
P/B Ratio23.4211.478.8513.25—11.6024.239.052.957.572.83
P/FCF———————————
P/OCF———————————

P/E links to full P/E history page with 30-year chart

PLSE EV Ratios

Enterprise-value multiples — capital-structure-neutral measures of total business value

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
EV / Revenue—2434.67——155.45279.82—————
EV / EBITDA———————————
EV / EBIT———————————
EV / FCF———————————

PLSE Profitability

Margins and return-on-capital ratios measuring operating efficiency

Margins

Full margin charts and quarterly trend are on the Earnings History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Gross Margin-360.0%-360.0%——-1606.3%-38.8%—————
Operating Margin-21982.6%-21982.6%——-8293.9%-4443.9%—————
Net Profit Margin-20794.6%-20794.6%——-8357.9%-4489.4%—————

Return on Capital

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
ROE-74.4%-74.4%-67.3%-200.5%-349.9%-217.3%-185.5%-94.8%-66.8%-71.7%-48.9%
ROA-63.7%-63.7%-55.9%-61.6%-88.6%-133.3%-119.5%-81.7%-62.3%-67.2%-46.8%
ROIC-876.1%-876.1%-567.8%-301.1%-281.9%-235.6%-143.2%-157.1%-98.5%-58.8%-43.2%
ROCE-73.1%-73.1%-64.3%-70.1%-98.7%-158.6%-140.4%-91.4%-65.9%-70.8%-49.2%

PLSE Leverage & Debt

Solvency and debt-coverage ratios — lower is generally safer

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Debt / Equity0.090.090.080.21—0.320.500.22———
Debt / EBITDA———————————
Net Debt / Equity—-0.91-0.95-0.79—-0.49-0.05-0.01-0.77-0.07-0.08
Net Debt / EBITDA———————————
Debt / FCF———————————
Interest Coverage———-39.61———————

Net cash position: cash ($81M) exceeds total debt ($8M)

PLSE Liquidity & Efficiency

Short-term solvency ratios and asset-utilisation metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Current Ratio10.5310.5311.886.7610.394.302.955.9219.4217.3916.40
Quick Ratio10.5110.5111.886.7610.393.622.955.9219.4217.3916.40
Cash Ratio10.1910.1911.746.6110.223.362.705.7019.1717.2016.14
Asset Turnover—0.00——0.010.03—————
Inventory Turnover11.8411.84———0.34—————
Days Sales Outstanding—285.74———15.70—————

PLSE Shareholder Yields

Earnings, FCF, buyback, and dividend yields — total returns to shareholders

Dividends

Full dividend history and growth charts are on the Dividend History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Dividend Yield———————————
Payout Ratio———————————

Total Shareholder Return Metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Earnings Yield———————————
FCF Yield———————————
Buyback Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%
Total Shareholder Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%
Shares Outstanding—$67M$58M$48M$34M$28M$23M$21M$17M$15M$11M

Key Metrics

Growth RegimeMixed
ProfitabilityNegative
Balance SheetAdequate
Cash FlowBurning
Top Statement Risk

Clinical trial execution failure

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2026Q1)

Speculative Premium Over Fundamental Reality

As reported in financial statements, the company trades at a price-to-sales multiple of 5625.76, a figure that suggests investors are pricing the stock as a binary call option on future clinical success rather than on any current fundamental revenue generation or earnings capacity.

The extreme P/S ratio indicates that the market is disregarding traditional valuation metrics in favor of long-term intellectual property potential. This valuation disconnect warrants caution, as it implies that any delay in regulatory milestones could lead to a significant downward re-rating of the equity.

Negative Margins Reflect Development Phase

Based on recent quarterly data, the company's gross margin of 7.7% in 2026Q1, following periods of negative margins, suggests that the firm is still struggling to achieve unit-level profitability as it transitions from experimental dermatology to more complex surgical applications.

The persistent negative operating margins, which reached -47.8% in the most recent quarter, highlight the heavy burden of R&D and clinical trial costs. Investors should monitor whether the shift toward cardiac applications can eventually drive the scale necessary to move margins into positive territory.

Capital Erosion Through R&D Intensity

According to historical data, the company's ROIC has remained consistently negative, with a recent reading of -2.3% in 2026Q1, reflecting the massive capital consumption required to sustain the development of the proprietary nanosecond pulse power platform before achieving commercial viability.

The inability to generate positive returns on invested capital is a direct consequence of the company's pre-revenue status and high fixed-cost structure. This trend suggests that capital is being deployed for long-term asset creation rather than immediate earnings, which warrants further investigation into the efficiency of these R&D expenditures.

Working Capital Instability and Turnover

As indicated by the reported financial figures, the company's cash conversion cycle remains deeply negative at -584 days, a metric that reflects the highly irregular nature of inventory management and the lack of a predictable, high-volume commercial sales cycle for its medical devices.

The extreme volatility in the cash conversion cycle suggests that the company is still in the process of establishing its supply chain and distribution channels. The high days-payable-outstanding figure may indicate a reliance on supplier credit, which warrants monitoring as the company attempts to scale its operations.

Adequate Runway Despite Cash Burn

Based on the latest balance sheet, the company maintains a current ratio of 7.26, providing a liquidity buffer that appears sufficient to fund near-term clinical trials despite the ongoing cash burn observed in recent quarters, as reported in financial statements.

The strong current ratio is primarily supported by cash reserves rather than operational cash flow, which suggests that the company is well-positioned to avoid immediate dilutive financing. However, the rapid consumption of these assets necessitates a clear path to commercialization to ensure long-term solvency.

Misapplication of Traditional Revenue Multiples

The most commonly misapplied metric for this business model is the price-to-sales ratio, which obscures the company's true value by ignoring the fact that current revenue is largely transactional and does not reflect the potential of the recurring razor/razorblade model.

Using P/S to value a pre-commercial firm like Pulse Biosciences is misleading because it fails to account for the high cost of clinical validation and the lack of a stable installed base. Analysts should instead focus on the utilization rate per console and the progress of clinical trial milestones as more accurate indicators of future value.

Download Financial Ratios Data

Includes 30+ ratios · 12 years · Updated daily

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PLSE — Frequently Asked Questions

Quick answers to the most common questions about buying PLSE stock.

What is Pulse Biosciences, Inc.'s P/E ratio?

Pulse Biosciences, Inc.'s current P/E ratio is -26.0x. This places it at the 50th percentile of its historical range.

What is Pulse Biosciences, Inc.'s ROE?

Pulse Biosciences, Inc.'s return on equity (ROE) is -74.4%. The historical average is -116.6%.

Is PLSE stock overvalued?

Based on historical data, Pulse Biosciences, Inc. is trading at a P/E of -26.0x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.

What are Pulse Biosciences, Inc.'s profit margins?

Pulse Biosciences, Inc. has -360.0% gross margin and -21982.6% operating margin.