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PLSEPulse Biosciences, Inc.
$28.03$1.9B
Overview & Verdict
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PLSE logoPulse Biosciences, Inc.(PLSE)Earnings, Financials & Key Ratios

PLSE•NASDAQ
$28.03
Price updated Jul 7, 2026
SectorHealthcareIndustryMedical InstrumentsSub-IndustrySurgical and interventional devices
AboutPulse Biosciences, Inc. operates as a novel bioelectric medicine company. It offers CellFX System, a tunable, software-enabled, and console-based platform that delivers nano second duration pulses of electrical energy to non-thermally clear targeted cells while sparing adjacent non-cellular tissue to treat a various medical condition by using its Nano-Pulse Stimulation technology. The company was formerly known as Electroblate, Inc. and changed its name to Pulse Biosciences, Inc. in December 2015. Pulse Biosciences, Inc. was incorporated in 2014 and is headquartered in Hayward, California.Show more
  • Revenue$350K
  • EBITDA-$76M-37.7%
  • Net Income-$73M-35.8%
  • EPS (Diluted)-1.08-17.4%
  • Gross Margin-360%
  • EBITDA Margin-21676.57%
  • Operating Margin-21982.57%
  • Net Margin-20794.57%
  • ROE-74.45%-10.6%

PLSE Price & Volume

Pulse Biosciences, Inc. (PLSE) stock price & volume — 10-year historical chart

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Nascent Commercialization Faces Persistent Clinical Burn Risks

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Adequate
Cash Flow:Burning
Primary Risk:Clinical trial execution failure

Key Thesis Takeaways

  • Pulse Biosciences is currently navigating a high-risk transition from a pure-play R&D entity to a commercial-stage medical device company, characterized by significant quarterly cash outflows of approximately $14.6 million.
  • While the company maintains a relatively clean balance sheet with a debt-to-equity ratio of 0.11, the lack of consistent revenue growth and negative gross margins suggest that the underlying business model has yet to achieve commercial viability.
  • Investors should monitor the company's ability to scale its nanosecond pulse power platform while managing the substantial $12.6 million in quarterly R&D expenses that continue to drive cumulative deficits of $481.9 million.

Verdict Logic

the company's inability to generate consistent revenue, evidenced by a 2026Q1 operating margin of -47.8%, suggests that the current valuation is not supported by fundamental commercial performance.

PLSE Growth Metrics

Pulse Biosciences, Inc. (PLSE) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-20.63%
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-23.78%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-10.1%

Return on Capital

10 Years-88.26%
5 Years-92.97%
3 Years-69.17%
Last Year-73.07%

PLSE Recent Earnings

Pulse Biosciences, Inc. (PLSE) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 10/12 qtrs (91%)●Beat Revenue 2/12 qtrs (67%)
Q2 2026Latest
May 4, 2026
Metric
Actual
Est
EPS
$0.27+15.6%
$0.32
Rev
$400,000+60.0%
$250,000
Q1 2026
Feb 19, 2026
Metric
Actual
Est
EPS
$0.26+1.9%
$0.27
Rev
$264,000+76.0%
$150,000
Q4 2025
Nov 5, 2025
Metric
Actual
Est
EPS
$0.29+6.5%
$0.31
Rev
$86,000-61.8%
$225,000
Q3 2025
Aug 12, 2025
Metric
Actual
Est
EPS
$0.28-7.7%
$0.26
Rev
—
$500,000
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 4, 2026
$0.27vs $0.32+15.6%
$400,000vs $250,000+60.0%
Q1 2026Feb 19, 2026
$0.26vs $0.27+1.9%
$264,000vs $150,000+76.0%
Q4 2025Nov 5, 2025
$0.29vs $0.31+6.5%
$86,000vs $225,000-61.8%
Q3 2025Aug 12, 2025
$0.28vs $0.26-7.7%
—vs $500,000
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Pulse Biosciences, Inc. (PLSE)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
PLSE logoPLSEPulse Biosciences, Inc.Current
$28.03$1.94B-25.95—-20794.57%-74.45%—
INVA logoINVAInnoviva, Inc.
$22.25$1.64B6.7418.52%118.91%47.59%—
NVCR logoNVCRNovoCure Limited
$17.72$2.02B-14.528.28%-25.66%-50.82%—
ATEC logoATECAlphatec Holdings, Inc.
$9.38$1.42B-9.7724.95%-21.07%-443.09%—
ANAB logoANABAnaptysBio, Inc.
$67.33$2.9B-146.36157.01%-11.53%——
INMD logoINMDInMode Ltd.
$14.54$921.24M10.17-6.16%23.27%13.28%—

Compare PLSE vs Peers

Pulse Biosciences, Inc. (PLSE) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs INVA

Most directly comparable listed peer for PLSE.

Scale Benchmark

vs ABT

Larger-name benchmark to compare PLSE against a more recognizable public peer.

Peer Set

Compare Top 5

vs INVA, NVCR, ATEC, ANAB

PLSE SEC Filings & Documents

Pulse Biosciences, Inc. (PLSE) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 6, 2026·SEC

Material company update

May 4, 2026·SEC

Material company update

Apr 27, 2026·SEC

10-K Annual Reports

2
FY 2026

Feb 19, 2026·SEC

FY 2025

Mar 31, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

May 14, 2026·SEC

FY 2025

Nov 5, 2025·SEC

FY 2025

Aug 12, 2025·SEC

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PLSE Frequently Asked Questions

Pulse Biosciences, Inc. (PLSE) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Pulse Biosciences, Inc.'s revenue?

Pulse Biosciences, Inc. (PLSE) reported $0.8M in revenue for fiscal year 2025.

Is PLSE profitable?

Pulse Biosciences, Inc. (PLSE) reported a net loss of $74.6M for fiscal year 2025.

Dividend & Returns
What is PLSE's return on equity?

Pulse Biosciences, Inc. (PLSE) has a return on equity (ROE) of -74.4%. Negative ROE indicates the company is unprofitable.

What is Pulse Biosciences, Inc.'s free cash flow?

Pulse Biosciences, Inc. (PLSE) had negative free cash flow of $55.5M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in PLSE back in 2014?

Total return calculator · dividends reinvested · 12+ years of data

See returns →