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MIRMMirum Pharmaceuticals, Inc.
$121.91$6.1B
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MIRM logoMirum Pharmaceuticals, Inc.(MIRM)Earnings, Financials & Key Ratios

MIRM•NASDAQ
$121.91
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Rare Disease Biopharma
AboutMirum Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of novel therapies for debilitating rare and orphan diseases. The company's lead product candidate is LIVMARLI, an investigational oral drug for the treatment of progressive familial intrahepatic cholestasis disease, as well as for the treatment of Alagille syndrome and biliary atresia disease. It also develops Volixibat drug for treatment of intrahepatic cholestasis of pregnancy and primary sclerosing cholangitis. Mirum Pharmaceuticals, Inc. was incorporated in 2018 and is headquartered in Foster City, California.Show more
  • Revenue$521M+54.7%
  • EBITDA$2M+103.3%
  • Net Income-$23M+73.4%
  • EPS (Diluted)-0.47+74.6%
  • Gross Margin80.71%+6.5%
  • EBITDA Margin0.4%+102.1%
  • Operating Margin-4.25%+83.7%
  • Net Margin-4.48%+82.8%
  • ROE-8.65%+76.7%

MIRM Price & Volume

Mirum Pharmaceuticals, Inc. (MIRM) stock price & volume — 10-year historical chart

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Commercial Scaling Drives Mirum Toward Operational Inflection

Investment Thesis • Updated 2026Q1

VerdictNeutral
Growth:Expanding
Profitability:Moderate
Financial:Healthy
Cash Flow:Improving
Primary Risk:Clinical label expansion failure

Key Thesis Takeaways

  • Mirum Pharmaceuticals is successfully transitioning from a clinical-stage developer to a commercial-scale rare disease platform, evidenced by a 49.8% year-over-year revenue growth in 2025Q4.
  • While the company is nearing an operating margin inflection point, having improved from -46.8% in 2023Q4 to -3.1% in 2025Q4, investors should remain cautious of the $1.5B retained earnings deficit and the $254.2M in goodwill that may pose future impairment risks.
  • The company's capital-light model, supported by a CapEx/Revenue ratio consistently below 0.5%, provides a pathway to self-sustaining operations if commercial momentum in its hepatology portfolio persists.

Verdict Logic

while the company shows promising revenue growth of 49.8% in 2025Q4, the $19.0M in quarterly stock-based compensation and the $1.5B accumulated deficit warrant further investigation into the quality of long-term earnings.

MIRM Growth Metrics

Mirum Pharmaceuticals, Inc. (MIRM) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years89.13%
TTM8.04%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-932.9%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-745.9%

Return on Capital

10 Years-36.41%
5 Years-33.41%
3 Years-15.12%
Last Year-3.75%

MIRM Recent Earnings

Mirum Pharmaceuticals, Inc. (MIRM) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)●Beat Revenue 7/12 qtrs (58%)
Q2 2026Latest
May 6, 2026
Metric
Actual
Est
EPS
$13.43-3257.5%
$0.40
Rev
$160M+7.9%
$148M
Q1 2026
Feb 25, 2026
Metric
Actual
Est
EPS
$0.11-650.0%
$0.02
Rev
$149M+4.5%
$143M
Q4 2025
Nov 4, 2025
Metric
Actual
Est
EPS
$0.05+150.0%
$0.10
Rev
$133M-5.6%
$141M
Q3 2025
Aug 6, 2025
Metric
Actual
Est
EPS
$0.12+61.3%
$0.31
Rev
$128M-1.8%
$130M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 6, 2026
$13.43vs $0.40-3257.5%
$160Mvs $148M+7.9%
Q1 2026Feb 25, 2026
$0.11vs $0.02-650.0%
$149Mvs $143M+4.5%
Q4 2025Nov 4, 2025
$0.05vs $0.10+150.0%
$133Mvs $141M-5.6%
Q3 2025Aug 6, 2025
$0.12vs $0.31+61.3%
$128Mvs $130M-1.8%
Based on last 12 quarters of dataView full earnings history →

Latest MIRM News

Recent stock market news and headlines for Mirum Pharmaceuticals, Inc. (MIRM)

ETF Trends·Jun 25, 2026
Biotech ETF Index Surges 10% After Rebalance

After a sweeping semi-annual rebalance, the biotech index underlying the ALPS Medical Breakthroughs ETF (SBIO) gained over 10% in just six trading days beginning June 18. Key Takeaways: SBIO's underlying index gained 10.01% in six trading days following its June 18 semi-annual rebalance.

Zacks Investment Research·Jun 17, 2026
MIRM, INCY Report Positive Rare Disease Data as FDA Begins NDA Review (Revised)

Mirum and Incyte's zilurgisertib cut new bone lesion formation in rare disease FOP, as the FDA begins Priority Review of the NDA with a Sept. 26, 2026, decision date.

Zacks Investment Research·Jun 16, 2026
MIRM, INCY Report Positive Rare Disease Data as FDA Begins NDA Review (Revised)

Mirum and Incyte's zilurgisertib cut new bone lesion formation in rare disease FOP, as the FDA begins Priority Review of the NDA with a Sept. 26, 2026, decision date.

Zacks Investment Research·Jun 15, 2026
MIRM, INCY Report Positive Rare Disease Data as FDA Begins NDA Review

Mirum and Incyte's zilurgisertib cut new bone lesion formation in rare disease FOP, as the FDA begins Priority Review of the NDA with a Sept. 26, 2026, decision date.

Peers Comparison

Key metrics vs top competitors for Mirum Pharmaceuticals, Inc. (MIRM)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
MIRM logoMIRMMirum Pharmaceuticals, Inc.Current
$121.91$6.12B-259.3854.74%-4.48%-8.65%—
ALNY logoALNYAlnylam Pharmaceuticals, Inc.
$313.04$41.77B134.3565.19%13.46%98.29%—
RARE logoRAREUltragenyx Pharmaceutical Inc.
$33.70$3.31B-5.7820.13%-91.03%——
ACAD logoACADACADIA Pharmaceuticals Inc.
$25.77$4.41B11.2511.87%34.3%35.65%—
FOLD logoFOLDAmicus Therapeutics, Inc.
$14.49$4.55B-164.8520.05%-4.27%-12.02%—
PTCT logoPTCTPTC Therapeutics, Inc.
$85.44$7.09B10.98114.51%-22.58%——

Compare MIRM vs Peers

Mirum Pharmaceuticals, Inc. (MIRM) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ALNY

Most directly comparable listed peer for MIRM.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare MIRM against a more recognizable public peer.

Peer Set

Compare Top 5

vs ALNY, RARE, ACAD, FOLD

MIRM SEC Filings & Documents

Mirum Pharmaceuticals, Inc. (MIRM) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 6, 2026·SEC

Material company update

May 4, 2026·SEC

Material company update

Apr 27, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 25, 2026·SEC

FY 2025

Feb 26, 2025·SEC

FY 2024

Mar 15, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 6, 2026·SEC

FY 2025

Nov 4, 2025·SEC

FY 2025

Aug 6, 2025·SEC

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MIRM Frequently Asked Questions

Mirum Pharmaceuticals, Inc. (MIRM) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Mirum Pharmaceuticals, Inc.'s revenue?

Mirum Pharmaceuticals, Inc. (MIRM) reported $409.7M in revenue for fiscal year 2025.

How fast is Mirum Pharmaceuticals, Inc. growing?

Mirum Pharmaceuticals, Inc. (MIRM) grew revenue by 54.7% over the past year. This is strong growth.

Is MIRM profitable?

Mirum Pharmaceuticals, Inc. (MIRM) reported a net loss of $798.8M for fiscal year 2025.

Dividend & Returns
What is MIRM's return on equity?

Mirum Pharmaceuticals, Inc. (MIRM) has a return on equity (ROE) of -8.6%. Negative ROE indicates the company is unprofitable.

What is Mirum Pharmaceuticals, Inc.'s free cash flow?

Mirum Pharmaceuticals, Inc. (MIRM) had negative free cash flow of $172.6M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in MIRM back in 2018?

Total return calculator · dividends reinvested · 8+ years of data

See returns →