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MCRBSeres Therapeutics, Inc.
$7.71$74M
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MCRB logoSeres Therapeutics, Inc.(MCRB)Earnings, Financials & Key Ratios

MCRB•NASDAQ
$7.71
12.0× P/E·Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryMicrobiome and Phage Therapeutics
AboutSeres Therapeutics, Inc., a microbiome therapeutics platform company, engages in developing bacterial consortia that are designed to functionally interact with host cells and tissues to treat disease. The company's lead product candidate is the SER-109, an oral microbiome therapeutic candidate that has completed Phase III clinical trial for the treatment of clostridium difficile infection (CDI). It is also developing SER-155, a cultivated bacteria microbiome drug, which is Phase Ib clinical trial to reduce incidences of gastrointestinal infections, bloodstream infections, and graft versus host diseases in immunocompromised patients receiving allogeneic hematopoietic stem cell transplantation and solid organ transplants. In addition, the company engages in the development of SER-287 and SER-301 that are in Phase Ib to treat ulcerative colitis; SER-401 for patients with metastatic melanoma; and SER-262 to treat Clostridioides difficile infection. It has license and collaboration agreements with Nestec Ltd. and Memorial Sloan Kettering Cancer Center. The company was formerly known as Seres Health, Inc. and changed its name to Seres Therapeutics, Inc. in May 2015. Seres Therapeutics, Inc. was incorporated in 2010 and is headquartered in Cambridge, Massachusetts.Show more
  • Revenue$789K
  • EBITDA-$90M+22.5%
  • Net Income$6M+4088.2%
  • EPS (Diluted)0.64+103.4%
  • Gross Margin-423.83%
  • EBITDA Margin-11386.31%
  • Operating Margin-11910.14%
  • Net Margin721.93%
  • ROE19.64%+1890.5%

MCRB Price & Volume

Seres Therapeutics, Inc. (MCRB) stock price & volume — 10-year historical chart

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Divestiture Driven Contraction Strains Clinical Liquidity

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Binary clinical trial failure

Key Thesis Takeaways

  • Seres Therapeutics has transitioned into a leaner, R&D-focused entity following the divestiture of its primary commercial asset, yet the firm faces significant sustainability challenges.
  • While the pivot aims to preserve specialized microbiome capabilities, the company's reliance on sporadic collaboration fees and a high fixed-cost structure creates a precarious financial outlook.
  • Investors should monitor the company's ability to extend its limited cash runway, as current operating losses and high debt levels necessitate potential dilutive financing to support ongoing clinical development.

Verdict Logic

the company's precarious liquidity position, highlighted by a cash balance of only $29.8 million against quarterly operating losses exceeding $20 million, suggests a high probability of near-term dilutive capital raises.

MCRB Growth Metrics

Seres Therapeutics, Inc. (MCRB) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-52.67%
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-164.29%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM48.25%

Return on Capital

10 Years-62.37%
5 Years-63.7%
3 Years-76.23%
Last Year-86.43%

MCRB Recent Earnings

Seres Therapeutics, Inc. (MCRB) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 7/12 qtrs (58%)●Beat Revenue 1/12 qtrs (17%)
Q2 2026Latest
May 5, 2026
Metric
Actual
Est
EPS
$2.08-10.6%
$1.88
Rev
$358,000+0.0%
$358,000
Q2 2026
Mar 12, 2026
Metric
Actual
Est
EPS
$1.89+20.9%
$2.39
Rev
$438,000-91.7%
$5M
Q4 2025
Nov 5, 2025
Metric
Actual
Est
EPS
$0.94+1780.0%
$0.05
Rev
$351,000-95.5%
$8M
Q3 2025
Aug 6, 2025
Metric
Actual
Est
EPS
$2.27+16.5%
$2.72
Rev
—
$6M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 5, 2026
$2.08vs $1.88-10.6%
$358,000vs $358,000+0.0%
Q2 2026Mar 12, 2026
$1.89vs $2.39+20.9%
$438,000vs $5M-91.7%
Q4 2025Nov 5, 2025
$0.94vs $0.05+1780.0%
$351,000vs $8M-95.5%
Q3 2025Aug 6, 2025
$2.27vs $2.72+16.5%
—vs $6M
Based on last 12 quarters of dataView full earnings history →

Latest MCRB News

Recent stock market news and headlines for Seres Therapeutics, Inc. (MCRB)

GlobeNewsWire·Jun 25, 2026
Seres Therapeutics to Host Webcast on July 8, 2026, to Discuss Results of Investigator-Sponsored Trial of Seres' SER-155 in Immune Checkpoint Inhibitor-Related Enterocolitis

CAMBRIDGE, Mass., June 25, 2026 (GLOBE NEWSWIRE) -- Seres Therapeutics, Inc. (Nasdaq: MCRB), a leading live biotherapeutics company, today announced that it will host a webcast to discuss top-line results from an investigator-sponsored trial (IST) evaluating SER-155 in patients with immune checkpoint inhibitor-related enterocolitis, a serious and frequent side effect of immune checkpoint inhibitor cancer therapy.

Peers Comparison

Key metrics vs top competitors for Seres Therapeutics, Inc. (MCRB)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
MCRB logoMCRBSeres Therapeutics, Inc.Current
$7.71$74.26M12.05—721.93%19.64%—
NKTR logoNKTRNektar Therapeutics
$73.15$1.43B-7.52-43.89%-284.18%-87%—
MIRM logoMIRMMirum Pharmaceuticals, Inc.
$121.91$6.12B-259.3854.74%-194.97%-289.33%—
ARWR logoARWRArrowhead Pharmaceuticals, Inc.
$86.55$12.19B-7094.2623258.15%-48.38%-55.09%—
RCKT logoRCKTRocket Pharmaceuticals, Inc.
$3.99$435.68M-1.99——-70.79%—
EVGN logoEVGNEvogene Ltd.
$0.44$3.78M-0.41-30.91%-255.9%-110.7%—

Compare MCRB vs Peers

Seres Therapeutics, Inc. (MCRB) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs NKTR

Most directly comparable listed peer for MCRB.

Scale Benchmark

vs JNJ

Larger-name benchmark to compare MCRB against a more recognizable public peer.

Peer Set

Compare Top 5

vs NKTR, MIRM, ARWR, RCKT

MCRB SEC Filings & Documents

Seres Therapeutics, Inc. (MCRB) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 5, 2026·SEC

Material company update

Mar 16, 2026·SEC

Material company update

Mar 12, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 12, 2026·SEC

FY 2025

Mar 13, 2025·SEC

FY 2024

Mar 5, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 5, 2026·SEC

FY 2025

Nov 5, 2025·SEC

FY 2025

Aug 6, 2025·SEC

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MCRB Frequently Asked Questions

Seres Therapeutics, Inc. (MCRB) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Seres Therapeutics, Inc.'s revenue?

Seres Therapeutics, Inc. (MCRB) reported $1.1M in revenue for fiscal year 2025.

Is MCRB profitable?

Seres Therapeutics, Inc. (MCRB) reported a net loss of $46.9M for fiscal year 2025.

Dividend & Returns
What is MCRB's return on equity?

Seres Therapeutics, Inc. (MCRB) has a return on equity (ROE) of 19.6%. This is reasonable for most industries.

What is Seres Therapeutics, Inc.'s free cash flow?

Seres Therapeutics, Inc. (MCRB) had negative free cash flow of $42.4M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in MCRB back in 2012?

Total return calculator · dividends reinvested · 14+ years of data

See returns →