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DYAIDyadic International, Inc.
$1.06$39M
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DYAI logoDyadic International, Inc.(DYAI)Earnings, Financials & Key Ratios

DYAI•NASDAQ
$1.06
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryDrug Discovery and Antibody Platforms
AboutDyadic International, Inc., a biotechnology platform company, develops, produces, and sells enzymes and other proteins in the United States. The company utilizes its patented and proprietary C1 platform and other technologies to conduct research, development, and commercial activities for the development and manufacturing of human and animal vaccines and drugs, such as virus like particles and antigens, monoclonal antibodies, bi/tri-specific antibodies, fab antibody fragments, Fc-fusion proteins, biosimilars and/or biobetters, and other therapeutic enzymes and proteins. It offers DYAI-100, SARS-CoV-2-RBD antigen vaccine candidate towards a first-in-human Phase 1 clinical trial, is to validate to serve as proof of concept for the development of next generation multivariant COVID-19 vaccine candidates. The company has a research and development agreement with VTT Technical Research Centre of Finland, Ltd.; strategic research services agreement with Biotechnology Developments for Industry in Pharmaceuticals, S.L.U.; and collaboration with Syngene International Limited. Dyadic International, Inc. was founded in 1979 and is headquartered in Jupiter, Florida.Show more
  • Revenue$1M-64.7%
  • EBITDA-$7M-28.4%
  • Net Income-$7M-26.8%
  • EPS (Diluted)-0.23-15.0%
  • Gross Margin-88.25%-234.1%
  • EBITDA Margin-560.63%-264.2%
  • Operating Margin-579.88%-243.5%
  • Net Margin-597.63%-259.6%
  • ROE-397.8%-185.9%

DYAI Price & Volume

Dyadic International, Inc. (DYAI) stock price & volume — 10-year historical chart

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Persistent Operating Losses Threaten Capital Structure Stability

Investment Thesis • Updated 2026Q1

VerdictNegative: The company's inability to generate positive free cash flow
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Limited operational cash runway

Key Thesis Takeaways

  • Dyadic International faces a precarious fundamental outlook characterized by erratic, milestone-dependent revenue that fails to cover a rigid SG&A cost structure exceeding $1.2M per quarter.
  • The company's reliance on equity-based compensation and a deteriorating balance sheet, which recently saw equity fall to -$407.7K, suggests significant liquidity risks.
  • Investors should monitor the company's ability to secure non-dilutive capital, as the current model remains unable to achieve self-sustaining free cash flow.

Verdict Logic

combined with a negative equity position of -$407.7K, suggests that the current business model faces severe liquidity constraints.

DYAI Growth Metrics

Dyadic International, Inc. (DYAI) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years14.59%
5 Years-5.11%
3 Years-25.08%
TTM-11.04%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-25.13%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-7.85%

Return on Capital

10 Years-51.11%
5 Years-83.49%
3 Years-95.76%
Last Year-104.01%

DYAI Recent Earnings

Dyadic International, Inc. (DYAI) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 1/12 qtrs (10%)●Beat Revenue 2/12 qtrs (20%)
Q2 2026Latest
May 13, 2026
Metric
Actual
Est
EPS
$0.05-25.0%
$0.04
Rev
$1M+22.9%
$903,750
Q2 2026
Mar 25, 2026
Metric
Actual
Est
EPS
$0.06-100.0%
$0.03
Rev
$564,345-58.0%
$1M
Q4 2025
Nov 12, 2025
Metric
Actual
Est
EPS
$0.06-50.0%
$0.04
Rev
$1M-13.3%
$1M
Q3 2025
Aug 13, 2025
Metric
Actual
Est
EPS
$0.06+0.0%
$0.06
Rev
$463,449-69.1%
$2M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 13, 2026
$0.05vs $0.04-25.0%
$1Mvs $903,750+22.9%
Q2 2026Mar 25, 2026
$0.06vs $0.03-100.0%
$564,345vs $1M-58.0%
Q4 2025Nov 12, 2025
$0.06vs $0.04-50.0%
$1Mvs $1M-13.3%
Q3 2025Aug 13, 2025
$0.06vs $0.06+0.0%
$463,449vs $2M-69.1%
Based on last 12 quarters of dataView full earnings history →

Latest DYAI News

Recent stock market news and headlines for Dyadic International, Inc. (DYAI)

GlobeNewsWire·20h ago
Global Collaborations Continue to Validate Dyadic's C1 Platform and Expands Commercial Potential

Global Collaborations Continue to Validate Dyadic's C1 Platform and Expand Commercial Opportunity Dyadic's Ebola preparedness work highlights C1's potentia

GlobeNewsWire·Jun 29, 2026
Dyadic Expands IP Protection and Business Development Activities in Japan

JUPITER, Fla., June 29, 2026 (GLOBE NEWSWIRE) -- Dyadic International, Inc. (Nasdaq: DYAI) (“Dyadic” or the “Company”), d/b/a Dyadic Applied BioSolutions, a biotechnology company focused on the development and commercialization of scalable microbial protein production platforms for use across life sciences, food, nutrition, industrial, and biopharmaceutical sectors, today announced that the Japan Patent Office has allowed claims covering its proprietary Thermothelomyces heterothallica recombinant protein expression technology.

Newsfile Corp·Jun 22, 2026
An Interview with the President & COO: How Dyadic is Commercializing Its Protein Platform Across Multi-Billion-Dollar Markets

SmallCaps Daily Sits Down with Joe Hazelton to Discuss Dyadic's Product Strategy, Strategic Partnerships, and Long-Term Growth Vision New York, New York--(Newsfile Corp. - June 22, 2026) - Dyadic Applied BioSolutions, Inc. (NASDAQ: DYAI) ("Dyadic" or the "Company") is entering the next phase of its growth strategy as it expands commercialization efforts across Life Sciences, Food & Nutrition, and Bio-industrial markets. SmallCaps Daily sat down with President and Chief Operating Officer Joe Hazelton to discuss the Company's product portfolio, strategic partnerships, and growing opportunities in non-animal proteins.

Peers Comparison

Key metrics vs top competitors for Dyadic International, Inc. (DYAI)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
DYAI logoDYAIDyadic International, Inc.Current
$1.06$38.63M-4.61-64.74%-597.63%-397.8%—
CDXS logoCDXSCodexis, Inc.
$2.60$236.33M-5.2018.61%-40.96%-68.09%—
GEVO logoGEVOGevo, Inc.
$1.46$355.38M-10.43849.33%-19.38%-7.19%—
TWST logoTWSTTwist Bioscience Corporation
$91.03$5.67B-70.0220.32%-19.85%-17.46%—
SEER logoSEERSeer, Inc.
$2.22$122.06M-1.7315.57%-468.74%-26.58%—
BEAM logoBEAMBeam Therapeutics Inc.
$37.92$3.9B-46.81120.01%-49.17%-5.89%—

Compare DYAI vs Peers

Dyadic International, Inc. (DYAI) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs CDXS

Most directly comparable listed peer for DYAI.

Scale Benchmark

vs MRK

Larger-name benchmark to compare DYAI against a more recognizable public peer.

Peer Set

Compare Top 5

vs CDXS, GEVO, TWST, SEER

DYAI SEC Filings & Documents

Dyadic International, Inc. (DYAI) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 13, 2026·SEC

Material company update

Mar 30, 2026·SEC

Material company update

Mar 25, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 25, 2026·SEC

FY 2025

Mar 26, 2025·SEC

FY 2024

Mar 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 13, 2026·SEC

FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 13, 2025·SEC

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DYAI Frequently Asked Questions

Dyadic International, Inc. (DYAI) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Dyadic International, Inc.'s revenue?

Dyadic International, Inc. (DYAI) reported $3.0M in revenue for fiscal year 2025. This represents a 1308% increase from $0.2M in 2003.

How fast is Dyadic International, Inc. growing?

Dyadic International, Inc. (DYAI) saw revenue decline by 64.7% over the past year.

Is DYAI profitable?

Dyadic International, Inc. (DYAI) reported a net loss of $7.3M for fiscal year 2025.

Dividend & Returns
What is DYAI's return on equity?

Dyadic International, Inc. (DYAI) has a return on equity (ROE) of -397.8%. Negative ROE indicates the company is unprofitable.

What is Dyadic International, Inc.'s free cash flow?

Dyadic International, Inc. (DYAI) had negative free cash flow of $5.7M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in DYAI back in 2003?

Total return calculator · dividends reinvested · 23+ years of data

See returns →