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CDXSCodexis, Inc.
$2.60$236M
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CDXS logoCodexis, Inc.(CDXS)Earnings, Financials & Key Ratios

CDXS•NASDAQ
$2.60
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryLife Science Tools and Reagents
AboutCodexis, Inc. discovers, develops, and sells enzymes and other proteins. It offers biocatalyst products and services; intermediate chemicals products that are used for further chemical processing; and Codex biocatalyst panels and kits that enable customers to perform chemistry screening. The company also provides biocatalyst screening and protein engineering services. In addition, it offers CodeEvolver protein engineering technology platform, which helps in developing and delivering biocatalysts that perform chemical transformations and enhance the efficiency and productivity of manufacturing processes. The company's platform is also used to discover novel biotherapeutic drug candidates for targeted human diseases, as well as for molecular biology and in vitro diagnostic enzymes. It sells its products to pharmaceutical manufacturers through its direct sales and business development force in the United States and Europe. The company was incorporated in 2002 and is headquartered in Redwood City, California.Show more
  • Revenue$70M+18.6%
  • EBITDA-$33M+43.6%
  • Net Income-$44M+32.6%
  • EPS (Diluted)-0.50+43.8%
  • Gross Margin86.73%+19.5%
  • EBITDA Margin-47%+52.5%
  • Operating Margin-54.46%+44.8%
  • Net Margin-62.47%+43.2%
  • ROE-74.88%+11.9%

CDXS Price & Volume

Codexis, Inc. (CDXS) stock price & volume — 10-year historical chart

Loading chart...

Persistent Revenue Volatility Masks Structural Solvency Risks

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Persistent liquidity and solvency

Key Thesis Takeaways

  • Codexis faces a challenging outlook characterized by extreme revenue lumpiness, as evidenced by quarterly fluctuations between $7.5M and $38.9M, which complicates long-term operational planning.
  • While the company maintains high gross margins often exceeding 80%, the inability to achieve consistent operating scale has resulted in a massive accumulated deficit of $615.5M.
  • Investors should remain cautious as the firm's reliance on debt financing, which has surged to $72.9M, continues to pressure the balance sheet amidst persistent cash burn.

Verdict Logic

the company's reliance on debt to fund operations, evidenced by a total debt load of $72.9M against a shrinking cash buffer of $37.0M, presents a high risk of further shareholder dilution.

CDXS Growth Metrics

Codexis, Inc. (CDXS) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years5.35%
5 Years0.38%
3 Years-20.22%
TTM56.76%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM57.04%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM63.04%

Return on Capital

10 Years-32.89%
5 Years-31.14%
3 Years-42.59%
Last Year-30.93%

CDXS Recent Earnings

Codexis, Inc. (CDXS) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 7/12 qtrs (58%)●Beat Revenue 6/12 qtrs (50%)
Q2 2026Latest
May 7, 2026
Metric
Actual
Est
EPS
$0.10+9.1%
$0.11
Rev
$15M+5.0%
$15M
Q2 2026
Mar 11, 2026
Metric
Actual
Est
EPS
$0.11+1000.0%
$0.01
Rev
$39M+8.6%
$36M
Q4 2025
Nov 6, 2025
Metric
Actual
Est
EPS
$0.22-46.7%
$0.15
Rev
$9M-76.0%
$36M
Q3 2025
Aug 13, 2025
Metric
Actual
Est
EPS
$0.16+5.9%
$0.17
Rev
$15M-21.3%
$19M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$0.10vs $0.11+9.1%
$15Mvs $15M+5.0%
Q2 2026Mar 11, 2026
$0.11vs $0.01+1000.0%
$39Mvs $36M+8.6%
Q4 2025Nov 6, 2025
$0.22vs $0.15-46.7%
$9Mvs $36M-76.0%
Q3 2025Aug 13, 2025
$0.16vs $0.17+5.9%
$15Mvs $19M-21.3%
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Codexis, Inc. (CDXS)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
CDXS logoCDXSCodexis, Inc.Current
$2.60$236.33M-5.2018.61%-62.47%-74.88%—
GEVO logoGEVOGevo, Inc.
$1.46$355.38M-10.43849.33%-19.38%-7.19%—
BEAM logoBEAMBeam Therapeutics Inc.
$37.92$3.9B-46.81120.01%-49.17%-5.89%—
TRMK logoTRMKTrustmark Corporation
$46.23$2.71B12.4934.75%19%10.75%—
NUVB logoNUVBNuvation Bio Inc.
$5.67$1.97B-9.45698.96%-102.06%-44.1%—
RCKT logoRCKTRocket Pharmaceuticals, Inc.
$4.07$444.42M-2.02——-70.79%—

Compare CDXS vs Peers

Codexis, Inc. (CDXS) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs GEVO

Most directly comparable listed peer for CDXS.

Scale Benchmark

vs LLY

Larger-name benchmark to compare CDXS against a more recognizable public peer.

Peer Set

Compare Top 5

vs GEVO, BEAM, TRMK, NUVB

CDXS SEC Filings & Documents

Codexis, Inc. (CDXS) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 7, 2026·SEC

Material company update

Apr 14, 2026·SEC

Material company update

Mar 11, 2026·SEC

10-K Annual Reports

4
FY 2026

Mar 11, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 13, 2025·SEC

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CDXS Frequently Asked Questions

Codexis, Inc. (CDXS) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Codexis, Inc.'s revenue?

Codexis, Inc. (CDXS) reported $78.1M in revenue for fiscal year 2025. This represents a 544% increase from $12.1M in 2006.

How fast is Codexis, Inc. growing?

Codexis, Inc. (CDXS) grew revenue by 18.6% over the past year. This is strong growth.

Is CDXS profitable?

Codexis, Inc. (CDXS) reported a net loss of $32.0M for fiscal year 2025.

Dividend & Returns
What is CDXS's return on equity?

Codexis, Inc. (CDXS) has a return on equity (ROE) of -74.9%. Negative ROE indicates the company is unprofitable.

What is Codexis, Inc.'s free cash flow?

Codexis, Inc. (CDXS) had negative free cash flow of $22.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in CDXS back in 2006?

Total return calculator · dividends reinvested · 20+ years of data

See returns →