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ATHEAlterity Therapeutics Limited
$5.49$93M
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ATHE logoAlterity Therapeutics Limited(ATHE)Earnings, Financials & Key Ratios

ATHE•NASDAQ
$5.49
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutAlterity Therapeutics Limited engages in the research and development of therapeutic drugs to treat Alzheimer's disease, Huntington disease, Parkinson's disease, and other neurological disorders in Australia. The company's lead drug candidate is ATH434 that has completed Phase I clinical trial for the treatment of Parkinson's disease. It is also developing PBT2 that has completed Phase IIa clinical trial to treat Alzheimer's disease. The company was formerly known as Prana Biotechnology Limited and changed its name to Alterity Therapeutics Limited in April 2019. Alterity Therapeutics Limited was incorporated in 1997 and is headquartered in Melbourne, Australia.Show more
  • Revenue$5M+35.3%
  • EBITDA-$15M+25.7%
  • Net Income-$12M+36.5%
  • EPS (Diluted)-1.14+63.5%
  • Gross Margin97.66%+3.2%
  • EBITDA Margin-267.44%+45.1%
  • Operating Margin-267.96%+45.1%
  • Net Margin-223.35%+53.1%
  • ROE-43.23%+58.6%

ATHE Price & Volume

Alterity Therapeutics Limited (ATHE) stock price & volume — 10-year historical chart

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Clinical Development Costs Outpace Revenue Generation Potential

Investment Thesis • Updated 2026Q2

VerdictNegative: The company's total lack of commercial revenue and a $12.8 million quarterly operating loss in 2026Q2 suggest that the firm remains in a high-burn
Growth:Mixed
Profitability:Negative
Financial:Adequate
Cash Flow:Burning
Primary Risk:Clinical trial binary outcome

Key Thesis Takeaways

  • Alterity Therapeutics remains a high-risk, pre-commercial biotechnology firm entirely dependent on non-recurring R&D tax incentives to offset significant clinical trial expenditures.
  • The company's long-term viability hinges on the successful progression of its lead candidate, ATH434, as it currently lacks any commercial product revenue to support its $12.8 million quarterly operating loss.
  • Investors should remain cautious regarding the persistent reliance on external capital, which has resulted in an accumulated deficit of $234.1 million and ongoing dilution risks.

Verdict Logic

binary-outcome phase that warrants extreme caution.

ATHE Growth Metrics

Alterity Therapeutics Limited (ATHE) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years40.86%
5 Years-
3 Years2.01%
TTM-11.93%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-28.69%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM54.13%

Return on Capital

10 Years-57.2%
5 Years-65.83%
3 Years-69.46%
Last Year-51.74%

Peers Comparison

Key metrics vs top competitors for Alterity Therapeutics Limited (ATHE)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
ATHE logoATHEAlterity Therapeutics LimitedCurrent
$5.49$93.01M-6.9435.32%-223.35%-43.23%—
PRTA logoPRTAProthena Corporation plc
$9.68$506.78M-2.14-92.84%-260.92%-49.88%—
ACAD logoACADACADIA Pharmaceuticals Inc.
$26.20$4.49B11.4411.87%34.3%35.65%—
SAVA logoSAVACassava Sciences, Inc.
$1.32$63.77M-2.54——-95.77%—
AVXL logoAVXLAnavex Life Sciences Corp.
$2.71$251.14M-5.02——-38.76%—
IONS logoIONSIonis Pharmaceuticals, Inc.
$86.33$14.27B-36.2733.87%-30.87%-58.57%—

Compare ATHE vs Peers

Alterity Therapeutics Limited (ATHE) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PRTA

Most directly comparable listed peer for ATHE.

Scale Benchmark

vs BIIB

Larger-name benchmark to compare ATHE against a more recognizable public peer.

Peer Set

Compare Top 5

vs PRTA, ACAD, SAVA, AVXL

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ATHE Frequently Asked Questions

Alterity Therapeutics Limited (ATHE) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Alterity Therapeutics Limited's revenue?

Alterity Therapeutics Limited (ATHE) reported $7.6M in revenue for fiscal year 2025. This represents a 851% increase from $0.8M in 2002.

How fast is Alterity Therapeutics Limited growing?

Alterity Therapeutics Limited (ATHE) grew revenue by 35.3% over the past year. This is strong growth.

Is ATHE profitable?

Alterity Therapeutics Limited (ATHE) reported a net loss of $34.2M for fiscal year 2025.

Dividend & Returns
What is ATHE's return on equity?

Alterity Therapeutics Limited (ATHE) has a return on equity (ROE) of -43.2%. Negative ROE indicates the company is unprofitable.

What is Alterity Therapeutics Limited's free cash flow?

Alterity Therapeutics Limited (ATHE) had negative free cash flow of $18.8M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in ATHE back in 2002?

Total return calculator · dividends reinvested · 24+ years of data

See returns →