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CYTKCytokinetics, Incorporated
$85.56$10.5B
Overview & Verdict
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CYTK logoCytokinetics, Incorporated(CYTK)Earnings, Financials & Key Ratios

CYTK•NASDAQ
$85.56
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutCytokinetics, Incorporated, a late-stage biopharmaceutical company, focuses on discovering, developing, and commercializing muscle activators and inhibitors as potential treatments for debilitating diseases. The company develops small molecule drug candidates primarily engineered to impact muscle function and contractility. Its drug candidates include omecamtiv mecarbil, a novel cardiac myosin activator that is in Phase III clinical trial in patients with heart failure; and reldesemtiv, a skeletal muscle troponin activator, which is in Phase III clinical trial to treat amyotrophic lateral sclerosis and spinal muscular atrophy. The company also develops CK-136, a novel cardiac troponin activator that is in Phase I clinical trial; aficamten, a novel cardiac myosin inhibitor, which is in Phase III clinical trial for the treatment of patients with symptomatic obstructive hypertrophic cardiomyopathy; and CK-3772271, a small molecule cardiac myosin inhibitor that is in Phase I clinical trial. Cytokinetics, Incorporated has a strategic alliance with Astellas Pharma Inc. The company was incorporated in 1997 and is headquartered in South San Francisco, California.Show more
  • Revenue$88M+376.6%
  • EBITDA-$603M-14.4%
  • Net Income-$785M-33.2%
  • EPS (Diluted)-6.54-24.3%
  • Gross Margin88.5%+105.1%
  • EBITDA Margin-684.44%+76.0%
  • Operating Margin-695.44%+76.0%
  • Net Margin-891.6%+72.1%

CYTK Price & Volume

Cytokinetics, Incorporated (CYTK) stock price & volume — 10-year historical chart

Loading chart...

Binary Clinical Risk Overshadows Rapid Cash Depletion

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Binary Regulatory Approval Risk

Key Thesis Takeaways

  • Cytokinetics remains a high-stakes, binary-outcome biotechnology play heavily dependent on the successful commercialization of its lead cardiovascular candidate, aficamten.
  • While the company is aggressively scaling commercial infrastructure, as evidenced by a $104.9 million SG&A expense in 2026Q1, the persistent reliance on milestone-driven revenue and deep operating losses of $183.6 million per quarter create significant financial fragility.
  • Investors should monitor the company's ability to manage its $1.0 billion debt load against a rapidly shrinking cash balance, which fell from $882.2 million in 2025Q4 to $129.8 million in 2026Q1.

Verdict Logic

the rapid depletion of cash reserves from $882.2 million to $129.8 million in a single quarter suggests an urgent need for dilutive financing to sustain operations ahead of potential regulatory milestones.

CYTK Growth Metrics

Cytokinetics, Incorporated (CYTK) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years11.88%
5 Years9.54%
3 Years-2.36%
TTM450.6%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-34.84%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-29.06%

Return on Capital

10 Years-38.02%
5 Years-46.56%
3 Years-55.12%
Last Year-50.1%

CYTK Recent Earnings

Cytokinetics, Incorporated (CYTK) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 4/12 qtrs (33%)●Beat Revenue 4/12 qtrs (33%)
Q2 2026Latest
May 5, 2026
Metric
Actual
Est
EPS
$1.67+0.0%
$1.67
Rev
$19M+127.2%
$9M
Q1 2026
Feb 24, 2026
Metric
Actual
Est
EPS
$1.50-1.4%
$1.48
Rev
$18M+156.3%
$7M
Q4 2025
Nov 5, 2025
Metric
Actual
Est
EPS
$1.54+3.1%
$1.59
Rev
$2M-75.9%
$8M
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$1.12+16.4%
$1.34
Rev
$67M+3131.1%
$2M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 5, 2026
$1.67vs $1.67+0.0%
$19Mvs $9M+127.2%
Q1 2026Feb 24, 2026
$1.50vs $1.48-1.4%
$18Mvs $7M+156.3%
Q4 2025Nov 5, 2025
$1.54vs $1.59+3.1%
$2Mvs $8M-75.9%
Q3 2025Aug 7, 2025
$1.12vs $1.34+16.4%
$67Mvs $2M+3131.1%
Based on last 12 quarters of dataView full earnings history →

Latest CYTK News

Recent stock market news and headlines for Cytokinetics, Incorporated (CYTK)

Fool - Investing News·1 day ago
iShares Russell 2000 Value vs. Morningstar Small Cap: Which ETF Suits Your Portfolio Best?

IWN delivered a 37.4% one-year return but carries higher fees, while ISCV offers a 0.06% expense ratio and stronger dividend yield of 1.9%.

GlobeNewsWire·1 day ago
Cytokinetics Announces Three Late-Breaking Science Abstracts at the European Society of Cardiology (ESC) Congress 2026

Hot Line Presentation of Primary Results from ACACIA-HCM to Elaborate on Positive Topline Results in Patients with Non-Obstructive Hypertrophic Cardiomyopathy

Investors Business Daily·Jun 26, 2026
Entertainment Stocks Madison Square Garden, Sphere Rally To New Highs

Entertainment leader Sphere stock continues to outperform in the current market environment, setting new highs.

24/7 Wall Street·Jun 25, 2026
3 Under-the-Radar Biotech Takeover Targets for the Next Pharma Buying Spree

Large-cap pharma is back in the deal market. AbbVie's (NASDAQ: ABBV | ABBV Price Prediction) pending acquisition of Apogee Therapeutics signaled that big buyers will pay up for de-risked clinical assets.

GlobeNewsWire·Jun 17, 2026
Cytokinetics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

SOUTH SAN FRANCISCO, Calif., June 17, 2026 (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced that on June 15, 2026 it granted stock options to purchase an aggregate of 24,784 shares of common stock and 16,429 restricted stock units (RSUs) that will be settled in shares of common stock upon vesting and 2,242 performance stock units (PSUs) that, if earned, will be settled in shares of common stock upon vesting to 12 employees, whose employment commenced in May and June, 2026, as a material inducement to their employment.

Peers Comparison

Key metrics vs top competitors for Cytokinetics, Incorporated (CYTK)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
CYTK logoCYTKCytokinetics, IncorporatedCurrent
$85.56$10.54B-13.08376.56%-891.6%——
MDGL logoMDGLMadrigal Pharmaceuticals, Inc.
$545.36$12.57B-42.44432.05%-27.32%-50.15%—
KRYS logoKRYSKrystal Biotech, Inc.
$368.60$10.87B53.8933.94%53.92%19.25%—
RCUS logoRCUSArcus Biosciences, Inc.
$30.25$3.05B-9.19-4.26%-156.36%-68.97%—
ACAD logoACADACADIA Pharmaceuticals Inc.
$26.20$4.49B11.4411.87%34.3%35.65%—
FOLD logoFOLDAmicus Therapeutics, Inc.
$14.49$4.55B-164.8520.05%-4.27%-12.02%—

Compare CYTK vs Peers

Cytokinetics, Incorporated (CYTK) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs MDGL

Most directly comparable listed peer for CYTK.

Scale Benchmark

vs LLY

Larger-name benchmark to compare CYTK against a more recognizable public peer.

Peer Set

Compare Top 5

vs MDGL, KRYS, RCUS, ACAD

CYTK SEC Filings & Documents

Cytokinetics, Incorporated (CYTK) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 5, 2026·SEC

Material company update

May 5, 2026·SEC

Material company update

Feb 24, 2026·SEC

10-K Annual Reports

2
FY 2026

Feb 26, 2026·SEC

FY 2025

Feb 27, 2025·SEC

10-Q Quarterly Reports

4
FY 2026

May 5, 2026·SEC

FY 2025

Nov 5, 2025·SEC

FY 2025

Aug 7, 2025·SEC

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CYTK Frequently Asked Questions

Cytokinetics, Incorporated (CYTK) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Cytokinetics, Incorporated's revenue?

Cytokinetics, Incorporated (CYTK) reported $105.8M in revenue for fiscal year 2025. This represents a 829% increase from $11.4M in 2002.

How fast is Cytokinetics, Incorporated growing?

Cytokinetics, Incorporated (CYTK) grew revenue by 376.6% over the past year. This is strong growth.

Is CYTK profitable?

Cytokinetics, Incorporated (CYTK) reported a net loss of $829.6M for fiscal year 2025.

Dividend & Returns
What is Cytokinetics, Incorporated's free cash flow?

Cytokinetics, Incorporated (CYTK) had negative free cash flow of $548.9M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in CYTK back in 2002?

Total return calculator · dividends reinvested · 24+ years of data

See returns →