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XNCRXencor, Inc.
$14.89$1.1B
Overview & Verdict
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XNCR logoXencor, Inc.(XNCR)Earnings, Financials & Key Ratios

XNCR•NASDAQ
$14.89
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryDrug Discovery and Antibody Platforms
AboutXencor, Inc., a clinical stage biopharmaceutical company, focuses on the discovery and development of engineered monoclonal antibody and cytokine therapeutics to treat patients with cancer and autoimmune diseases. The company provides Sotrovimab that targets the SARS-CoV-2 virus; Ultomiris for the treatment of patients with paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome; and Monjuvi for the treatment of patients with relapsed or refractory diffuse large B-cell lymphoma. It develops Plamotamab, a tumor-targeted antibody, which is in Phase I clinical trial to treat non-Hodgkin lymphoma; Vudalimab, a bispecific antibody, which is in Phase II clinical trial to treat metastatic castration-resistant prostate cancer and other solid tumor types; and Tidutamab that is in Phase II clinical trial to treat neuroendocrine tumors. The company is also developing XmAb306, which is in Phase I clinical trial to treat solid tumors; XmAb104 and XmAb841, which are in Phase I clinical trial to treat patients with selected solid tumors; XmAb564 that is in Phase I clinical trial to treat autoimmune diseases; AMG 509, which is in Phase I clinical trial to treat prostate cancer; XmAb819 for patients with renal cell carcinoma; and Novartis XmAb. It develops VIR-3434, which is in Phase II clinical trial for patients with hepatitis B virus infection; VIR-2482 that is in Phase 1/2 clinical trial to trat influenza A; VIR-7832, which is in Phase 1b/2a trial to treat mild-to-moderate COVID-19; and BMS-986414 + BMS-986413 is in Phase 2/3 NIH ACTIV-2 trial in treating COVID-19. The company develops AIMab7195 to reduce blood serum levels of IgE that mediates allergic responses and allergic disease; Obexelimab to treat autoimmune disease; and Xpro1595 to treat patients with Alzheimer's disease, mild cognitive impairment, and depression. It has a license agreement with Caris Life Sciences. Xencor, Inc. was incorporated in 1997 and is headquartered in Monrovia, California.Show more
  • Revenue$126M+13.7%
  • EBITDA-$167M-0.4%
  • Net Income-$92M+60.5%
  • EPS (Diluted)-1.24+65.4%
  • Gross Margin91.63%-8.4%
  • EBITDA Margin-132.98%+11.6%
  • Operating Margin-141.35%+12.5%
  • Net Margin-73.2%+65.2%
  • ROE-14.04%+59.5%

XNCR Price & Volume

Xencor, Inc. (XNCR) stock price & volume — 10-year historical chart

Loading chart...

Erratic Milestone Revenue Masks Deep Cash Burn

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Critical Cash Runway Depletion

Key Thesis Takeaways

  • Xencor's reliance on unpredictable milestone-based revenue, which saw a 59.7% contraction in 2025Q4, creates significant volatility that complicates long-term financial forecasting.
  • While the company maintains high gross margins often exceeding 90%, these are consistently neutralized by heavy R&D expenditures that frequently exceed $50 million per quarter.
  • Investors should monitor the critical depletion of cash reserves, which fell to $14.2 million in 2026Q1, as the firm's structural reliance on external financing to fund its clinical pipeline remains a primary risk factor.

Verdict Logic

the company's cash position has reached a critical low of $14.2 million as of 2026Q1, suggesting an urgent need for dilutive financing to sustain its ongoing R&D-heavy clinical operations.

XNCR Growth Metrics

Xencor, Inc. (XNCR) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years16.29%
5 Years0.47%
3 Years-8.62%
TTM-32.48%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM19.49%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM27.76%

Return on Capital

10 Years-10.07%
5 Years-12.48%
3 Years-19.41%
Last Year-21.59%

XNCR Recent Earnings

Xencor, Inc. (XNCR) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 7/12 qtrs (58%)●Beat Revenue 6/12 qtrs (50%)
Q2 2026Latest
May 6, 2026
Metric
Actual
Est
EPS
$1.71-163.1%
$0.65
Rev
$5M-83.8%
$28M
Q1 2026
Feb 25, 2026
Metric
Actual
Est
EPS
$0.09+85.9%
$0.64
Rev
$28M-5.8%
$30M
Q4 2025
Nov 5, 2025
Metric
Actual
Est
EPS
$0.08+88.9%
$0.72
Rev
$21M-29.9%
$30M
Q3 2025
Aug 6, 2025
Metric
Actual
Est
EPS
$0.41+47.4%
$0.78
Rev
$44M+78.9%
$24M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 6, 2026
$1.71vs $0.65-163.1%
$5Mvs $28M-83.8%
Q1 2026Feb 25, 2026
$0.09vs $0.64+85.9%
$28Mvs $30M-5.8%
Q4 2025Nov 5, 2025
$0.08vs $0.72+88.9%
$21Mvs $30M-29.9%
Q3 2025Aug 6, 2025
$0.41vs $0.78+47.4%
$44Mvs $24M+78.9%
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Xencor, Inc. (XNCR)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
XNCR logoXNCRXencor, Inc.Current
$14.89$1.09B-12.0113.65%-73.2%-14.04%—
RCUS logoRCUSArcus Biosciences, Inc.
$29.98$3.02B-9.11-4.26%-156.36%-68.97%—
MGNX logoMGNXMacroGenics, Inc.
$4.57$290.48M-3.870.78%-44.79%-147.8%—
IMVT logoIMVTImmunovant, Inc.
$38.60$7.92B-13.94——-68.16%—
ALKS logoALKSAlkermes plc
$55.14$9.19B38.56-5.25%9.78%8.82%—
ZYME logoZYMEZymeworks Inc.
$25.33$1.86B-23.4538.87%-126.33%-0.25%—

Compare XNCR vs Peers

Xencor, Inc. (XNCR) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs RCUS

Most directly comparable listed peer for XNCR.

Scale Benchmark

vs LLY

Larger-name benchmark to compare XNCR against a more recognizable public peer.

Peer Set

Compare Top 5

vs RCUS, MGNX, IMVT, ALKS

XNCR SEC Filings & Documents

Xencor, Inc. (XNCR) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 6, 2026·SEC

Material company update

May 5, 2026·SEC

Material company update

Apr 27, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 25, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 29, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 6, 2026·SEC

FY 2025

Nov 5, 2025·SEC

FY 2025

Aug 6, 2025·SEC

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XNCR Frequently Asked Questions

Xencor, Inc. (XNCR) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Xencor, Inc.'s revenue?

Xencor, Inc. (XNCR) reported $92.8M in revenue for fiscal year 2025. This represents a 1256% increase from $6.8M in 2011.

How fast is Xencor, Inc. growing?

Xencor, Inc. (XNCR) grew revenue by 13.7% over the past year. This is steady growth.

Is XNCR profitable?

Xencor, Inc. (XNCR) reported a net loss of $172.4M for fiscal year 2025.

Dividend & Returns
What is XNCR's return on equity?

Xencor, Inc. (XNCR) has a return on equity (ROE) of -14.0%. Negative ROE indicates the company is unprofitable.

What is Xencor, Inc.'s free cash flow?

Xencor, Inc. (XNCR) had negative free cash flow of $188.8M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in XNCR back in 2011?

Total return calculator · dividends reinvested · 15+ years of data

See returns →