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SILOSilo Pharma, Inc.
$5.66$5M
Overview & Verdict
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SILO logoSilo Pharma, Inc.(SILO)Earnings, Financials & Key Ratios

SILO•NASDAQ
$5.66
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutSilo Pharma Inc. operates as a developmental stage biopharmaceutical company. The company is developing therapeutics that address underserved conditions, including stress-induced psychiatric disorders, chronic pain conditions, and central nervous system (CNS) diseases. It focuses on developing traditional therapies and psychedelic treatments in formulations and drug delivery systems. The company's lead program, SPC-15, is an intranasal treatment targeting PTSD and stress-induced anxiety disorders. It is also developing SP-26, a time-release ketamine-loaded implant for fibromyalgia and chronic pain relief. In addition, the company's two preclinical programs comprise SPC-14, an intranasal compound for the treatment of Alzheimer's disease, and SPU-16, a CNS-homing peptide targeting multiple sclerosis (MS). The company's research and development programs are conducted through collaborations with Columbia University and the University of Maryland, Baltimore. The company was formerly known as Uppercut Brands, Inc. and changed its name to Silo Pharma, Inc. in September 2020. Silo Pharma, Inc. was incorporated in 2010 and is based in Sarasota, Florida.Show more
  • Revenue$72K
  • EBITDA-$4M+9.2%
  • Net Income-$4M+3.8%
  • EPS (Diluted)-7.50+58.0%
  • Gross Margin-1128.89%-1328.4%
  • EBITDA Margin-5921.09%+9.2%
  • Operating Margin-5936.95%+9.0%
  • Net Margin-5863.5%+3.8%
  • ROE-74.56%+4.9%

SILO Price & Volume

Silo Pharma, Inc. (SILO) stock price & volume — 10-year historical chart

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Clinical Development Costs Drive Persistent Equity Erosion

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Stable
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Dilutive financing dependency

Key Thesis Takeaways

  • Silo Pharma remains in a high-risk developmental phase, characterized by a stagnant revenue profile of $18,000 per quarter and an increasing reliance on external capital to fund clinical research.
  • While the company has successfully pivoted toward biotechnology, the lack of a commercialized product engine and a net loss of $1.6 million in 2026Q1 suggest significant long-term solvency risks.
  • Investors should monitor the company's ability to reach clinical milestones before its $3.9 million cash reserve is fully exhausted by ongoing R&D expenditures.

Verdict Logic

the company's reliance on dilutive financing to cover operating losses exceeding $1 million per quarter, combined with a shrinking cash position of $3.9 million, presents an unfavorable risk-reward profile for long-term investors.

SILO Growth Metrics

Silo Pharma, Inc. (SILO) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years0%
TTM0%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-4.77%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM56.85%

Return on Capital

10 Years-79.28%
5 Years-53.32%
3 Years-61.24%
Last Year-67.35%

SILO Recent Earnings

Silo Pharma, Inc. (SILO) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 1/12 qtrs (25%)●Beat Revenue 4/12 qtrs (100%)
Q2 2026Latest
May 14, 2026
Metric
Actual
Est
EPS
$0.12+62.5%
$0.32
Rev
$18,026+0.1%
$18,000
Q2 2026
Mar 27, 2026
Metric
Actual
Est
EPS
$0.07
—
Rev
$18,026
—
Q4 2025
Nov 13, 2025
Metric
Actual
Est
EPS
$0.12
—
Rev
$18,025
—
Q3 2025
Aug 13, 2025
Metric
Actual
Est
EPS
$0.19
—
Rev
$18,025
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 14, 2026
$0.12vs $0.32+62.5%
$18,026vs $18,000+0.1%
Q2 2026Mar 27, 2026
$0.07
$18,026
Q4 2025Nov 13, 2025
$0.12
$18,025
Q3 2025Aug 13, 2025
$0.19
$18,025
Based on last 12 quarters of dataView full earnings history →

Latest SILO News

Recent stock market news and headlines for Silo Pharma, Inc. (SILO)

Globe News Wire·Jun 29, 2026
Silo Pharma Advances SPC-15 PTSD Therapeutic with Drug-Device Robustness Study Ahead of Planned FDA Type C Meeting Request

Study designed to evaluate performance and formulation stability of proprietary nose-to-brain delivery system SARASOTA, FLA. , June 29, 2026 (GLOBE NEWSWIRE) -- Silo Pharma (Nasdaq: SILO) ("Silo" or "the Company"), a diversified developmental-stage biopharmaceutical company with a therapeutic focus on addressing underserved conditions, including stress-induced psychiatric disorders, chronic pain, and central nervous system (CNS) diseases, today announced that it has engaged its drug-device development partner Resyca to conduct a robustness study evaluating the microchip-based nasal spray system used for nose-to-brain delivery of SPC-15, the Company's lead intranasal prophylactic treatment for post-traumatic stress disorder (PTSD).

GlobeNewsWire·Jun 29, 2026
Silo Pharma Advances SPC-15 PTSD Therapeutic with Drug-Device Robustness Study Ahead of Planned FDA Type C Meeting Request

Study designed to evaluate performance and formulation stability of proprietary nose-to-brain delivery system

Globe News Wire·Jun 23, 2026
Silo Pharma Reports Positive Stability Data for SPC-15 PTSD Treatment, Advancing Program Toward First-in-Human Clinical Trial

Positive data supports the continued advancement of FDA Investigational New Drug (IND)- enabling development program SARASOTA, FLA. , June 23, 2026 (GLOBE NEWSWIRE) -- Silo Pharma (Nasdaq: SILO) ("Silo" or "the Company"), a developmental-stage biopharmaceutical company focused on novel therapeutics and drug delivery systems, today announced that it has confirmed the physical, chemical and microbiological stability of its investigational soft-mist intranasal prophylactic, SPC-15, through nine months of real-time testing.

GlobeNewsWire·Jun 23, 2026
Silo Pharma Reports Positive Stability Data for SPC-15 PTSD Treatment, Advancing Program Toward First-in-Human Clinical Trial

Positive data supports the continued advancement of FDA Investigational New Drug (IND)- enabling development program SARASOTA, FLA., June 23, 2026 (GLOBE NEWSWIRE) -- Silo Pharma (Nasdaq: SILO) (“Silo” or “the Company”), a developmental-stage biopharmaceutical company focused on novel therapeutics and drug delivery systems, today announced that it has confirmed the physical, chemical and microbiological stability of its investigational soft-mist intranasal prophylactic, SPC-15, through nine months of real-time testing.

GlobeNewsWire·Jun 18, 2026
Silo Pharma Regains Compliance with Nasdaq Minimum Bid Price Requirement

SARASOTA, FLA., June 18, 2026 (GLOBE NEWSWIRE) -- Silo Pharma (Nasdaq: SILO) (“Silo” or “the Company”), a developmental-stage biopharmaceutical company focused on novel therapeutics and drug delivery systems, today announced that it received confirmation from the Listing Qualifications Department of The Nasdaq Stock Market LLC informing the Company that, as of June 17, 2026, it has regained compliance with the minimum closing bid price requirement under Nasdaq Listing Rule 5550(a)(2). Silo's common stock continues to trade on the Nasdaq Capital Market, and the matter is now closed.

Peers Comparison

Key metrics vs top competitors for Silo Pharma, Inc. (SILO)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
SILO logoSILOSilo Pharma, Inc.Current
$5.66$5.12M-0.75—-5863.5%-74.56%—
CMPS logoCMPSCOMPASS Pathways plc
$12.99$1.25B-4.22——-151.02%—
MNMD logoMNMDMind Medicine (MindMed) Inc.
$20.69$2.04B-10.04——-102.48%—
ATAI logoATAIAtai Beckley N.V
$5.19$1.91B-1.781227.6%-19019.44%-366.21%—
CYBN logoCYBNCybin Inc.
$6.09$303.86M-13.66——-81%—
PSTV logoPSTVPlus Therapeutics, Inc.
$3.92$9.48M-0.55-10.49%-230.24%-198.48%—

Compare SILO vs Peers

Silo Pharma, Inc. (SILO) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs CMPS

Most directly comparable listed peer for SILO.

Scale Benchmark

vs HALO

Larger-name benchmark to compare SILO against a more recognizable public peer.

Peer Set

Compare Top 5

vs CMPS, MNMD, ATAI, CYBN

SILO SEC Filings & Documents

Silo Pharma, Inc. (SILO) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 2, 2026·SEC

Material company update

Feb 23, 2026·SEC

Material company update

Dec 29, 2025·SEC

10-K Annual Reports

4
FY 2026

Mar 27, 2026·SEC

FY 2025

Mar 28, 2025·SEC

FY 2024

Mar 25, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 14, 2026·SEC

FY 2025

Nov 13, 2025·SEC

FY 2025

Aug 13, 2025·SEC

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SILO Frequently Asked Questions

Silo Pharma, Inc. (SILO) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Silo Pharma, Inc.'s revenue?

Silo Pharma, Inc. (SILO) reported $0.1M in revenue for fiscal year 2025.

Is SILO profitable?

Silo Pharma, Inc. (SILO) reported a net loss of $4.8M for fiscal year 2025.

Dividend & Returns
What is SILO's return on equity?

Silo Pharma, Inc. (SILO) has a return on equity (ROE) of -74.6%. Negative ROE indicates the company is unprofitable.

What is Silo Pharma, Inc.'s free cash flow?

Silo Pharma, Inc. (SILO) had negative free cash flow of $3.8M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in SILO back in 2011?

Total return calculator · dividends reinvested · 15+ years of data

See returns →