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RNAAtrium Therapeutics, Inc.
$13.01$223M
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Atrium Therapeutics, Inc. (RNA) Financial Ratios

Latest Ratios: P/E Ratio -2.9x · EV/EBITDA N/A · ROE -9.4%. (2018–2025 historical series)

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly

RNA Valuation Multiples

Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
Market Cap$223M$1.2B$3.2B$661M$1.2B$985M$553M——
Enterprise Value$-43783598$968M$3.0B$486M$828M$676M$232M——
P/E Ratio →-2.90————————
P/S Ratio11.9566.30297.7769.12125.49105.5981.46——
P/B Ratio1.075.962.281.322.002.581.81——
P/FCF—————————
P/OCF—————————

P/E links to full P/E history page with 30-year chart

RNA EV Ratios

Enterprise-value multiples — capital-structure-neutral measures of total business value

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
EV / Revenue—52.00278.2250.7989.7472.4934.23——
EV / EBITDA—————————
EV / EBIT—————————
EV / FCF—————————

RNA Profitability

Margins and return-on-capital ratios measuring operating efficiency

Margins

Full margin charts and quarterly trend are on the Earnings History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
Gross Margin100.0%100.0%100.0%78.0%85.0%-984.9%-454.0%100.0%-2125.9%
Operating Margin-412.6%-412.6%-3477.4%-2464.4%-1939.6%-1265.8%-652.4%-747.4%-2769.9%
Net Profit Margin-411.9%-411.9%-2957.7%-2219.9%-1886.3%-1265.4%-653.5%-1066.6%-3148.8%

Return on Capital

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
ROE-9.4%-9.4%-33.5%-39.3%-36.3%-34.3%-36.8%——
ROA-8.3%-8.3%-29.4%-33.5%-32.6%-31.0%-20.6%-49.0%-299.7%
ROIC-10.0%-10.0%-37.0%-61.6%-83.6%-303.2%———
ROCE-9.0%-9.0%-37.6%-41.5%-36.3%-32.9%-21.8%-40.3%—

RNA Leverage & Debt

Solvency and debt-coverage ratios — lower is generally safer

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
Debt / Equity0.020.020.000.020.020.030.00——
Debt / EBITDA—————————
Net Debt / Equity—-1.28-0.15-0.35-0.57-0.81-1.05——
Net Debt / EBITDA—————————
Debt / FCF———————-39.75—
Interest Coverage——————-211.22-2.35-14.62

Net cash position: cash ($270M) exceeds total debt ($4M)

RNA Liquidity & Efficiency

Short-term solvency ratios and asset-utilisation metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
Current Ratio6.536.5315.737.5812.0013.8622.749.350.70
Quick Ratio6.536.5315.737.5812.0013.8622.749.350.70
Cash Ratio6.466.4615.327.3811.7713.6722.509.240.67
Asset Turnover—0.070.010.020.010.020.020.020.10
Inventory Turnover—————————
Days Sales Outstanding——945.31329.23153.3435.2264.54——

RNA Shareholder Yields

Earnings, FCF, buyback, and dividend yields — total returns to shareholders

Dividends

Full dividend history and growth charts are on the Dividend History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
Dividend Yield—————————
Payout Ratio—————————

Total Shareholder Return Metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
Earnings Yield—————————
FCF Yield—————————
Buyback Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%——
Total Shareholder Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%——
Shares Outstanding—$17M$112M$73M$52M$41M$22M$38M$21M

Key Metrics

Growth RegimeMixed
ProfitabilityNegative
Balance SheetVulnerable
Cash FlowBurning
Top Statement Risk

Clinical trial execution failure

Verified Source

Metrics are mathematically derived from official filings.

SEC 8-K (2026Q1)

Platform Premium Drives Valuation Multiples

According to recent market data, Atrium Therapeutics trades at a price-to-sales ratio of 12.12, a valuation that appears to reflect investor expectations for the AOC platform's long-term clinical success rather than any near-term earnings potential, as the company currently lacks commercial product revenue to support traditional multiples.

The absence of a meaningful P/E ratio, coupled with a P/B of 1.09, suggests that the market is pricing the firm as a speculative R&D engine. Investors should monitor whether this platform premium holds if clinical readouts fail to demonstrate clear superiority over existing therapeutic modalities.

Capital Compounding Remains Deeply Negative

Based on reported figures, the company's ROIC has consistently trended in negative territory, reaching -31.4% in 2025Q3, which indicates that the firm is currently destroying invested capital as it prioritizes aggressive clinical development over the achievement of positive returns on its research expenditures.

The persistent negative ROIC is a structural byproduct of the pre-commercial biotech model where massive R&D outlays are required before any revenue-generating assets reach the market. This trend warrants further investigation into whether the current capital allocation strategy will eventually yield a positive return once the AOC platform matures.

Working Capital Volatility Reflects Milestone Dependence

As reported in financial statements, the company's asset turnover ratio remains negligible at 0.02, highlighting the firm's reliance on non-recurring collaboration milestones rather than operational efficiency to drive its financial performance, which complicates the assessment of its underlying working capital management and long-term asset utilization.

The extreme fluctuations in DSO and DPO metrics suggest that the company's cash conversion cycle is dictated by the timing of partner payments rather than internal operational processes. Investors should be cautious of interpreting these ratios as indicators of operational health, as they are heavily skewed by the lumpy nature of milestone-based revenue recognition.

High Liquidity Masks Structural Burn Risks

As evidenced by the most recent quarterly data, the company maintains a current ratio of 13.04, which appears robust on the surface but must be interpreted in the context of a high-burn clinical development model that necessitates constant, significant capital outflows to maintain its current research pipeline.

While the current liquidity position provides a temporary buffer, the rapid consumption of cash to fund clinical trials suggests that the firm remains vulnerable to equity market volatility. The high current ratio is less a sign of operational strength and more a reflection of the capital raised to sustain future R&D activities.

Misapplication of Revenue-Based Valuation Metrics

The P/S ratio is frequently misapplied to Atrium Therapeutics, as it obscures the fact that the company's revenue is derived from non-recurring collaboration milestones rather than sustainable product sales, making it an unreliable metric for assessing the firm's true commercial viability or long-term growth trajectory.

Analysts should instead focus on cash runway duration and clinical milestone progress as more accurate indicators of value creation. Relying on P/S multiples in a pre-commercial biotech context may lead to an overestimation of the company's current market position and a misunderstanding of its fundamental financial risks.

Download Financial Ratios Data

Includes 30+ ratios · 8 years · Updated daily

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RNA — Frequently Asked Questions

Quick answers to the most common questions about buying RNA stock.

What is Atrium Therapeutics, Inc.'s P/E ratio?

Atrium Therapeutics, Inc.'s current P/E ratio is -2.9x. This places it at the 50th percentile of its historical range.

What is Atrium Therapeutics, Inc.'s ROE?

Atrium Therapeutics, Inc.'s return on equity (ROE) is -9.4%. The historical average is -31.6%.

Is RNA stock overvalued?

Based on historical data, Atrium Therapeutics, Inc. is trading at a P/E of -2.9x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.

What are Atrium Therapeutics, Inc.'s profit margins?

Atrium Therapeutics, Inc. has 100.0% gross margin and -412.6% operating margin.