Pyxis Oncology, Inc. (PYXS) Stock Price History
Historical prices from 2021 to 2026
- 1M
- +81.7%
- 3M
- +110.3%
- YTD
- +167.0%
- 1Y
- +169.3%
- 3Y
- +6.8%
- 5Y
- -25.3%
Loading 10-year price history...
PYXS Historical Performance
PYXS Annual Returns
Year-by-year price performance · 2021–2026
- 2021 annual price return
- -16.9%
- 2022 annual price return
- -88.3%
- 2023 annual price return
- +30.4%
- 2024 annual price return
- -24.3%
- 2025 annual price return
- -32.0%
- 2026 annual price return
- +27.8%
PYXS Stock Price Trajectory (2021–2026)
As of July 8, 2026, Pyxis Oncology, Inc. (PYXS) trades at $3.07, representing a +169.3% return over the past year. The stock has delivered a -76.7% total return over five years (-25.3% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $19.00 on October 8, 2021. From this peak, PYXS has corrected -83.8%, currently trading 31% above its 200-day moving average, indicating continued institutional support.
When compared to Healthcare sector peers IMVT (+144.2% 1Y), RCUS (+268.0% 1Y), and TPST (-86.0% 1Y), PYXS has underperformed the peer group average. Compare PYXS vs IMVT →
PYXS Historical Price Data · from 2021
Rows 1–50 of 1,190| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-07-07 | 2.47 | 3.20 | 2.38 | 3.07 | 2.45M | +24.80% |
| 2026-07-06 | 2.60 | 2.62 | 2.37 | 2.46 | 1.22M | -6.46% |
| 2026-07-02 | 2.79 | 3.00 | 2.63 | 2.63 | 690K | -7.72% |
| 2026-07-01 | 3.13 | 3.19 | 2.83 | 2.85 | 758K | -5.32% |
| 2026-06-30 | 2.49 | 3.40 | 2.45 | 3.01 | 7.02M | +5.24% |
| 2026-06-29 | 2.70 | 2.92 | 2.62 | 2.86 | 1.23M | +3.25% |
| 2026-06-26 | 2.24 | 3.00 | 2.20 | 2.77 | 0 | +24.22% |
| 2026-06-25 | 2.19 | 2.30 | 2.13 | 2.23 | 666K | +2.76% |
| 2026-06-24 | 2.14 | 2.31 | 2.10 | 2.17 | 646K | +3.33% |
| 2026-06-23 | 2.13 | 2.26 | 2.07 | 2.10 | 408K | -1.41% |
| 2026-06-22 | 2.06 | 2.18 | 2.04 | 2.13 | 500K | +4.93% |
| 2026-06-18 | 1.90 | 2.07 | 1.90 | 2.03 | 628K | +6.84% |
| 2026-06-17 | 1.78 | 1.96 | 1.78 | 1.90 | 384K | +8.57% |
| 2026-06-16 | 1.74 | 1.80 | 1.66 | 1.75 | 396K | +0.57% |
| 2026-06-15 | 1.77 | 1.83 | 1.66 | 1.74 | 166K | -1.14% |
| 2026-06-12 | 1.69 | 1.86 | 1.68 | 1.76 | 436K | +5.39% |
| 2026-06-11 | 1.66 | 1.73 | 1.54 | 1.67 | 805K | 0.00% |
| 2026-06-10 | 1.77 | 1.80 | 1.67 | 1.67 | 119K | -1.76% |
| 2026-06-09 | 1.68 | 1.78 | 1.65 | 1.70 | 172K | +0.59% |
| 2026-06-08 | 1.84 | 1.84 | 1.68 | 1.69 | 162K | -5.06% |
| 2026-06-05 | 1.68 | 1.87 | 1.62 | 1.78 | 843K | +2.89% |
| 2026-06-04 | 1.70 | 1.78 | 1.66 | 1.73 | 280K | +1.76% |
| 2026-06-03 | 1.70 | 1.75 | 1.67 | 1.70 | 179K | -0.58% |
| 2026-06-02 | 1.73 | 1.74 | 1.66 | 1.71 | 478K | -4.47% |
| 2026-06-01 | 1.76 | 1.83 | 1.72 | 1.79 | 490K | -0.56% |
| 2026-05-29 | 1.76 | 1.86 | 1.76 | 1.80 | 296K | +1.12% |
| 2026-05-28 | 1.71 | 1.82 | 1.64 | 1.78 | 650K | +2.89% |
| 2026-05-27 | 1.63 | 1.78 | 1.63 | 1.73 | 430K | +6.13% |
| 2026-05-26 | 2.00 | 2.04 | 1.57 | 1.63 | 1.28M | -16.84% |
| 2026-05-22 | 1.95 | 2.02 | 1.95 | 1.96 | 1.03M | +1.03% |
| 2026-05-21 | 2.01 | 2.08 | 1.93 | 1.94 | 347K | -3.00% |
| 2026-05-20 | 1.92 | 2.07 | 1.88 | 2.00 | 555K | +4.71% |
| 2026-05-19 | 1.93 | 2.00 | 1.90 | 1.91 | 261K | -5.45% |
| 2026-05-18 | 2.24 | 2.28 | 2.01 | 2.02 | 463K | -11.40% |
| 2026-05-15 | 2.17 | 2.35 | 1.96 | 2.28 | 982K | +3.17% |
| 2026-05-14 | 2.65 | 2.65 | 2.09 | 2.21 | 1.06M | -15.97% |
| 2026-05-13 | 2.59 | 2.73 | 2.56 | 2.63 | 352K | +1.15% |
| 2026-05-12 | 2.74 | 2.78 | 2.52 | 2.60 | 386K | -5.45% |
| 2026-05-11 | 2.66 | 2.92 | 2.66 | 2.75 | 753K | +0.36% |
| 2026-05-08 | 2.27 | 2.77 | 2.24 | 2.74 | 1.89M | +21.24% |
| 2026-05-07 | 2.30 | 2.33 | 2.18 | 2.26 | 686K | -1.74% |
| 2026-05-06 | 1.86 | 2.37 | 1.82 | 2.30 | 1.82M | +25.68% |
| 2026-05-05 | 1.88 | 1.95 | 1.73 | 1.83 | 1.10M | +3.98% |
| 2026-05-04 | 1.70 | 1.81 | 1.70 | 1.76 | 167K | +2.33% |
| 2026-05-01 | 1.69 | 1.73 | 1.69 | 1.72 | 102K | +1.18% |
| 2026-04-30 | 1.65 | 1.75 | 1.62 | 1.70 | 279K | +2.41% |
| 2026-04-29 | 1.70 | 1.73 | 1.64 | 1.66 | 278K | -2.35% |
| 2026-04-28 | 1.76 | 1.87 | 1.68 | 1.70 | 294K | -3.41% |
| 2026-04-27 | 1.90 | 1.97 | 1.72 | 1.76 | 566K | -7.37% |
| 2026-04-24 | 1.74 | 1.98 | 1.74 | 1.90 | 723K | +11.11% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
DCA Calculator
See how regular investing compounds over time.
Peer Comparison
Compare growth, multiples, and margins vs sector.
PYXS — Frequently Asked Questions
Quick answers to the most common questions about buying PYXS stock.
How has PYXS stock performed recently?
PYXS returned +169.3% over the past year, beating its 5-year annualized CAGR of -25.3%. The stock trades above its 200-day moving average, confirming the uptrend.
What is PYXS's all-time high price?
Pyxis Oncology, Inc. reached $19.00 on 2021-10-08. The 52-week high is $5.55. Current 1-year return of +169.3% places the stock closer to historical peaks.
Where can I download PYXS historical price data?
This page provides PYXS daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2021-2026, downloadable in CSV format.