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PCVXVaxcyte, Inc.
$60.67$8.8B
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PCVX logoVaxcyte, Inc.(PCVX)Earnings, Financials & Key Ratios

PCVX•NASDAQ
$60.67
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryVaccines and Infectious Disease
AboutVaxcyte, Inc., a clinical-stage biotechnology vaccine company, develops novel protein vaccines to prevent or treat bacterial infectious diseases. Its lead vaccine candidate is VAX-24, a 24-valent investigational pneumococcal conjugate vaccine that is in Phase 1/2 clinical trials to treat invasive pneumococcal disease and pneumonia. The company also develops VAX-XP to protect against emerging strains and address antibiotic resistance; VAX-A1, a conjugate vaccine candidate designed to treat Group A Strep; and VAX-PG, a novel protein vaccine candidate targeting keystone pathogen responsible for periodontitis. The company was formerly known as SutroVax, Inc. and changed its name to Vaxcyte, Inc. in May 2020. Vaxcyte, Inc. was incorporated in 2013 and is headquartered in San Carlos, California.Show more
  • Revenue$0
  • EBITDA-$899M-62.3%
  • Net Income-$767M-65.2%
  • EPS (Diluted)-5.63-48.2%
  • ROE-25.59%-25.4%

PCVX Price & Volume

Vaxcyte, Inc. (PCVX) stock price & volume — 10-year historical chart

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Clinical Development Costs Outpace Revenue Generation Potential

Investment Thesis • Updated 2026Q1

VerdictNeutral
Growth:Mixed
Profitability:Negative
Financial:Healthy
Cash Flow:Burning
Primary Risk:Clinical trial execution failure

Key Thesis Takeaways

  • Vaxcyte remains a pre-revenue, clinical-stage entity heavily reliant on external capital to fund its $312.8 million quarterly R&D expenditure as of 2026Q1.
  • While the company has successfully fortified its balance sheet to $3.3 billion in total assets, the persistent negative free cash flow and reliance on equity-based incentives create significant dilution risks for long-term shareholders.
  • Investors should monitor the company's ability to navigate competitive immunological hurdles and potential milestone obligations to Sutro Biopharma, which may materially impact future profitability.

Verdict Logic

while the company maintains a robust current ratio of 7.49, the lack of revenue and a $295.4 million quarterly free cash flow burn necessitate extreme caution regarding future capital dilution.

PCVX Growth Metrics

Vaxcyte, Inc. (PCVX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-85.73%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-68.46%

Return on Capital

10 Years-47.03%
5 Years-33.1%
3 Years-32.11%
Last Year-29.74%

PCVX Recent Earnings

Vaxcyte, Inc. (PCVX) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 3/12 qtrs (25%)
Q2 2026Latest
May 6, 2026
Metric
Actual
Est
EPS
$2.30-29.4%
$1.78
Rev
—
$13M
Q1 2026
Feb 24, 2026
Metric
Actual
Est
EPS
$1.80-17.7%
$1.53
Rev
—
$19M
Q4 2025
Nov 4, 2025
Metric
Actual
Est
EPS
$1.56-22.8%
$1.27
Rev
—
—
Q3 2025
Aug 6, 2025
Metric
Actual
Est
EPS
$1.22-8.9%
$1.12
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 6, 2026
$2.30vs $1.78-29.4%
—vs $13M
Q1 2026Feb 24, 2026
$1.80vs $1.53-17.7%
—vs $19M
Q4 2025Nov 4, 2025
$1.56vs $1.27-22.8%
—
Q3 2025Aug 6, 2025
$1.22vs $1.12-8.9%
—
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Vaxcyte, Inc. (PCVX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
PCVX logoPCVXVaxcyte, Inc.Current
$60.67$8.76B-10.78——-25.59%—
PFE logoPFEPfizer Inc.
$24.07$136.92B17.70-1.65%11.83%8.34%—
MRK logoMRKMerck & Co., Inc.
$128.86$318.26B17.701.18%13.62%17.91%—
GSK logoGSKGSK plc
$53.32$107.23B7.164.11%19.19%31.48%—
SNY logoSNYSanofi
$42.98$103.34B11.755.49%16.72%10.78%—
BNTX logoBNTXBioNTech SE
$94.29$23.84B-18.300.2%-44.95%-6.72%—

Compare PCVX vs Peers

Vaxcyte, Inc. (PCVX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PFE

Most directly comparable listed peer for PCVX.

Scale Benchmark

vs MRK

Larger-name benchmark to compare PCVX against a more recognizable public peer.

Peer Set

Compare Top 5

vs PFE, MRK, GSK, SNY

PCVX SEC Filings & Documents

Vaxcyte, Inc. (PCVX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 6, 2026·SEC

Material company update

Feb 24, 2026·SEC

Material company update

Feb 24, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 24, 2026·SEC

FY 2025

Feb 25, 2025·SEC

FY 2024

Feb 27, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 6, 2026·SEC

FY 2025

Nov 4, 2025·SEC

FY 2025

Aug 6, 2025·SEC

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PCVX Frequently Asked Questions

Vaxcyte, Inc. (PCVX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is PCVX profitable?

Vaxcyte, Inc. (PCVX) reported a net loss of $946.5M for fiscal year 2025.

Dividend & Returns
What is PCVX's return on equity?

Vaxcyte, Inc. (PCVX) has a return on equity (ROE) of -25.6%. Negative ROE indicates the company is unprofitable.

What is Vaxcyte, Inc.'s free cash flow?

Vaxcyte, Inc. (PCVX) had negative free cash flow of $771.7M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in PCVX back in 2017?

Total return calculator · dividends reinvested · 9+ years of data

See returns →