Pacific Biosciences of California, Inc. (PACB) Institutional Ownership

Based on Q1 2026 13F filings, institutional ownership of Pacific Biosciences of California, Inc. stands at 60.3%, held across 226 reporting institutions.

ARK Investment Management LLC is the largest reported institutional holder of PACB, with approximately 36,273,288 shares worth $0.05B as of Q1 2026.

Yes — 6 widely-followed marquee investors appear among the top 25 institutional holders of PACB, including ARK Investment Management LLC, MILLENNIUM MANAGEMENT LLC, TWO SIGMA INVESTMENTS, LP, RENAISSANCE TECHNOLOGIES LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP.

Our composite Smart Money Score for PACB is 60 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.

52 institutions opened new positions in PACB during Q1 2026, while 37 fully exited. 26 added to existing positions and 144 trimmed.

PACB institutional ownership fell by 31.05 percentage points quarter-over-quarter, with a net change of +15 holders.

The top 10 institutions account for 70.1% of all reported 13F value in PACB, and the top 25 account for 87.6%.

All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.