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OMEROmeros Corporation
$10.34$748M
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OMER logoOmeros Corporation(OMER)Earnings, Financials & Key Ratios

OMER•NASDAQ
$10.34
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryImmunology and Inflammation Therapies
AboutOmeros Corporation, a commercial-stage biopharmaceutical company, discovers, develops, and commercializes small-molecule and protein therapeutics, and orphan indications targeting inflammation, complement-mediated diseases, cancers related to dysfunction of the immune system, and addictive and compulsive disorders. The company's clinical programs include Narsoplimab (OMS721/MASP-2) that has completed pivotal studies for hematopoietic stem-cell transplant-associated thrombotic microangiopathy (HSCT-TMA); that is in Phase III clinical trial for immunoglobulin A nephropathy (IgAN) and atypical hemolytic uremic syndrome (aHUS); and Phase II clinical trial to treat COVID-19. Its clinical programs also consist of PPAR? (OMS405) that is in Phase II to treat opioid and nicotine addiction; PDE7 (OMS527), which is in Phase I trial for treating addiction and compulsive disorders, and movement disorders; and MASP-3 (OMS906) that is in Phase I trial for paroxysmal nocturnal hemoglobinuria (PNH) and other alternative pathway disorders. The company's preclinical programs comprise MASP-2-small-molecule inhibitors used for the treatment of aHUS, IgAN, HSCT-TMA, and age-related macular degeneration; longer-acting second generation antibody targeting MASP-2; and MASP-3-small-molecule inhibitors to treat PNH and other alternative pathway disorders. Its preclinical programs also include GPR174 Inhibitors and Chimeric Antigen Receptor (CAR) T-Cell and Adoptive T-Cell Therapies for various cancers; and G protein-coupled receptor targets for treating immunologic, immuno-oncologic, metabolic, CNS, cardiovascular, musculoskeletal, and other disorders. The company was incorporated in 1994 and is headquartered in Seattle, Washington.Show more
  • Revenue$0
  • EBITDA-$122M+27.6%
  • Net Income-$3M+97.9%
  • EPS (Diluted)-0.05+98.0%

OMER Price & Volume

Omeros Corporation (OMER) stock price & volume — 10-year historical chart

Loading chart...

Persistent Operational Losses Mask Critical Liquidity Constraints

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Critical liquidity and dilution

Key Thesis Takeaways

  • Omeros Corporation faces a precarious financial outlook characterized by a structural reliance on external capital to fund its $13.1 million quarterly R&D burn rate.
  • While the company reported a $56.1 million net income in 2026Q1, this figure is heavily distorted by non-operating fair value adjustments rather than core operational success.
  • Investors should remain cautious given the company's $310.6 million debt load and the critical depletion of cash reserves to just $1.9 million, which necessitates immediate and potentially dilutive financing to maintain clinical operations.

Verdict Logic

the company's cash and equivalents have dwindled to a critical $1.9 million, which is insufficient to support ongoing clinical obligations and suggests a high risk of shareholder dilution.

OMER Growth Metrics

Omeros Corporation (OMER) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM156.29%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM149.06%

Return on Capital

10 Years-84.17%
5 Years-53.95%
3 Years-54.06%
Last Year-55.17%

OMER Recent Earnings

Omeros Corporation (OMER) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 7/12 qtrs (58%)●Beat Revenue 1/12 qtrs (100%)
Q2 2026Latest
May 13, 2026
Metric
Actual
Est
EPS
$0.24+40.0%
$0.40
Rev
$10M+136.4%
$4M
Q2 2026
Mar 31, 2026
Metric
Actual
Est
EPS
$3.14+670.9%
$0.55
Rev
—
$2M
Q4 2025
Nov 13, 2025
Metric
Actual
Est
EPS
$0.19+67.2%
$0.58
Rev
—
—
Q3 2025
Aug 14, 2025
Metric
Actual
Est
EPS
$0.53+3.6%
$0.55
Rev
—
$312,500
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 13, 2026
$0.24vs $0.40+40.0%
$10Mvs $4M+136.4%
Q2 2026Mar 31, 2026
$3.14vs $0.55+670.9%
—vs $2M
Q4 2025Nov 13, 2025
$0.19vs $0.58+67.2%
—
Q3 2025Aug 14, 2025
$0.53vs $0.55+3.6%
—vs $312,500
Based on last 12 quarters of dataView full earnings history →

Latest OMER News

Recent stock market news and headlines for Omeros Corporation (OMER)

Invezz·Jun 26, 2026
Omeros stock crashes on regulatory setback: buy the dip?

Omeros Corp (OMER) stock is tumbling on Friday morning following a major regulatory setback in Europe that has caught investors off guard. Investors are bailing on OMER mostly because the European Medicines Agency's (EMA) expert panel has rejected its primary commercial asset.

Benzinga·Jun 26, 2026
FDA Approved, Europe Unconvinced: Omeros' Stem Cell Transplant Treatment Hits Regulatory Divide

The European Medicines Agency's Human Medicines Committee (CHMP) on Friday issued a negative opinion for Omeros Corp.'s (NASDAQ:OMER) narsoplimab.

Business Wire·Jun 26, 2026
Omeros Corporation Announces Update on European Marketing Authorization Application for Narsoplimab in TA-TMA

SEATTLE--(BUSINESS WIRE)--Omeros Corporation (Nasdaq: OMER) announced today an update on the review by the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) of the company's marketing authorization application (MAA) for narsoplimab for the treatment of hematopoietic stem cell transplant-associated thrombotic microangiopathy (TA-TMA). Following an oral explanation meeting with the CHMP held this week, at which Omeros presented its position together with.

Fool - Investing News·Jun 22, 2026
NovoCure vs. Omeros: Which Emerging Pharmaceutical Stock Is a Better Buy in 2026?

Both companies target serious health challenges, but their financials and risk profiles reveal sharply different paths for growth-focused investors.

The Motley Fool·Jun 20, 2026
Intellia Therapeutics vs. Omeros: Which Emerging Biotech Stock Is a Better Buy in 2026?

Intellia Therapeutics is leveraging its strategic partnership with Regeneron to advance a deep pipeline of CRISPR-based gene editing therapies. Omeros recently entered the commercial stage with the FDA approval of Yartemlea and a significant development deal with Novo Nordisk.

Peers Comparison

Key metrics vs top competitors for Omeros Corporation (OMER)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
OMER logoOMEROmeros CorporationCurrent
$10.34$748.36M-196.20————
ACAD logoACADACADIA Pharmaceuticals Inc.
$25.77$4.41B11.2511.87%34.3%35.65%—
PTCT logoPTCTPTC Therapeutics, Inc.
$85.44$7.09B10.98114.51%-22.58%——
RARE logoRAREUltragenyx Pharmaceutical Inc.
$33.70$3.31B-5.7820.13%-91.03%——
FOLD logoFOLDAmicus Therapeutics, Inc.
$14.49$4.55B-164.8520.05%-4.27%-12.02%—
HALO logoHALOHalozyme Therapeutics, Inc.
$80.78$9.58B31.5537.55%23.13%126.27%—

Compare OMER vs Peers

Omeros Corporation (OMER) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ACAD

Most directly comparable listed peer for OMER.

Scale Benchmark

vs IQV

Larger-name benchmark to compare OMER against a more recognizable public peer.

Peer Set

Compare Top 5

vs ACAD, PTCT, RARE, FOLD

OMER SEC Filings & Documents

Omeros Corporation (OMER) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 13, 2026·SEC

Material company update

Mar 31, 2026·SEC

Material company update

Jan 7, 2026·SEC

10-K Annual Reports

4
FY 2026

Mar 31, 2026·SEC

FY 2025

Mar 31, 2025·SEC

FY 2024

Apr 1, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 13, 2026·SEC

FY 2025

Nov 13, 2025·SEC

FY 2025

Aug 14, 2025·SEC

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OMER Frequently Asked Questions

Omeros Corporation (OMER) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Omeros Corporation's revenue?

Omeros Corporation (OMER) reported $9.9M in revenue for fiscal year 2025. This represents a 414% increase from $1.9M in 2007.

Is OMER profitable?

Yes, Omeros Corporation (OMER) is profitable, generating $86.2M in net income for fiscal year 2025 (871.0% net margin).

Dividend & Returns
What is Omeros Corporation's free cash flow?

Omeros Corporation (OMER) had negative free cash flow of $94.8M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in OMER back in 2007?

Total return calculator · dividends reinvested · 19+ years of data

See returns →