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NKTRNektar Therapeutics
$74.90$1.5B
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Nektar Therapeutics (NKTR) Financial Ratios

Latest Ratios: P/E Ratio -7.7x · EV/EBITDA N/A · ROE -217.9%. (1996–2025 historical series)

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly

NKTR Valuation Multiples

Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Market Cap$1.5B$713M$191M$107M$423M$2.5B$3.0B$3.8B$5.9B$9.3B$1.7B
Enterprise Value$1.6B$847M$250M$190M$466M$2.6B$3.0B$4.1B$6.0B$9.6B$1.9B
P/E Ratio →-7.70———————8.70——
P/S Ratio26.5012.911.941.194.5924.3019.8532.964.9630.2710.35
P/B Ratio14.077.943.150.821.153.642.822.693.45106.0419.44
P/FCF————————8.41——
P/OCF————————8.24——

P/E links to full P/E history page with 30-year chart

NKTR EV Ratios

Enterprise-value multiples — capital-structure-neutral measures of total business value

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
EV / Revenue—15.342.542.115.0625.4619.5435.685.0031.0511.50
EV / EBITDA————————8.57——
EV / EBIT————————8.23——
EV / FCF————————8.48——

NKTR Profitability

Margins and return-on-capital ratios measuring operating efficiency

Margins

Full margin charts and quarterly trend are on the Earnings History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Gross Margin100.0%100.0%68.8%59.3%76.5%75.6%87.3%81.4%98.0%90.1%81.7%
Operating Margin-236.8%-236.8%-106.9%-152.5%-261.0%-437.8%-248.5%-383.9%57.6%-19.4%-68.2%
Net Profit Margin-297.1%-297.1%-120.9%-306.3%-400.0%-514.0%-290.6%-384.5%57.1%-31.4%-92.8%

Return on Capital

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
ROE-217.9%-217.9%-124.1%-110.9%-70.4%-59.6%-35.8%-28.2%75.5%-109.9%-324.7%
ROA-56.2%-56.2%-33.9%-49.8%-40.3%-39.4%-25.3%-21.4%51.2%-17.9%-28.7%
ROIC-57.2%-57.2%-47.5%-33.1%-29.8%-36.6%-20.8%-18.9%49.2%-14.8%-35.6%
ROCE-55.7%-55.7%-35.7%-27.8%-28.7%-36.3%-24.9%-23.8%54.6%-12.6%-24.1%

NKTR Leverage & Debt

Solvency and debt-coverage ratios — lower is generally safer

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Debt / Equity1.661.661.690.900.360.210.140.290.142.792.82
Debt / EBITDA————————0.35——
Net Debt / Equity—1.490.960.630.120.17-0.050.220.032.742.14
Net Debt / EBITDA————————0.07——
Debt / FCF————————0.07——
Interest Coverage-4.99-4.99-3.24-9.90-11.62-10.06-10.96-8.4916.96-1.35-2.62

NKTR Liquidity & Efficiency

Short-term solvency ratios and asset-utilisation metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Current Ratio4.974.974.266.458.009.349.834.0217.535.825.90
Quick Ratio4.974.974.266.147.729.159.703.9817.395.635.75
Cash Ratio4.594.594.165.927.408.619.173.7416.285.275.39
Asset Turnover—0.200.320.230.130.090.100.060.550.600.29
Inventory Turnover———2.281.131.581.271.692.142.852.72
Days Sales Outstanding—11.765.979.1233.3280.5692.83117.2013.225.9534.59

NKTR Shareholder Yields

Earnings, FCF, buyback, and dividend yields — total returns to shareholders

Dividends

Full dividend history and growth charts are on the Dividend History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Dividend Yield———————————
Payout Ratio———————————

Total Shareholder Return Metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Earnings Yield————————11.5%——
FCF Yield————————11.9%——
Buyback Yield0.0%0.0%1.6%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%
Total Shareholder Yield0.0%0.0%1.6%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%
Shares Outstanding—$17M$14M$13M$12M$12M$12M$12M$12M$10M$9M

Key Metrics

Growth RegimeContracting
ProfitabilityNegative
Balance SheetVulnerable
Cash FlowBurning
Top Statement Risk

Imminent liquidity and solvency

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2026Q1)

Distressed Valuation Reflects Pipeline Uncertainty

Based on reported financial data, Nektar's P/S ratio of 22.52 appears disconnected from its contracting revenue base, suggesting that the market is pricing the firm as a distressed asset rather than a growth-oriented platform, with valuation multiples heavily skewed by the absence of positive earnings.

The lack of meaningful P/E or EV/EBITDA multiples underscores the market's focus on binary clinical outcomes rather than fundamental cash generation. Investors should monitor whether the current premium over book value is justified by the remaining immunology pipeline or if it represents a speculative floor that may collapse without further partnership validation.

Capital Efficiency Decaying Amidst Losses

As reported in recent financial statements, Nektar's ROIC has trended deeply into negative territory, reaching -7.1% in 2026Q1, which indicates that the company is currently destroying shareholder value by deploying capital into research programs that have yet to yield a sustainable return on invested capital.

The persistent negative ROIC highlights the structural challenge of a biotech model that consumes significant capital without achieving commercial scale. This trend suggests that management's capital allocation strategy has struggled to balance the high costs of clinical development against the diminishing returns of its legacy licensing portfolio.

Working Capital Volatility Impedes Operations

According to recent SEC filings, Nektar's asset turnover ratio remains extremely low at 0.02, illustrating the company's inability to generate meaningful revenue from its asset base and highlighting the inefficiency inherent in its current project-based, milestone-dependent business model compared to more established industry peers.

The erratic nature of the cash conversion cycle, compounded by high days sales outstanding, suggests that the company lacks leverage in its partnership agreements. This inefficiency warrants further investigation, as it indicates that the firm's operational structure is not optimized for the timely conversion of research milestones into liquid cash.

Liquidity Buffer Nears Critical Threshold

Based on the company's reported figures, the current ratio of 10.21 in 2026Q1 masks a precarious cash position, as the firm's liquidity is increasingly tied to non-liquid assets rather than the cash required to sustain its high-burn R&D operations through the next clinical inflection point.

While the current ratio appears high, it is misleading in the context of a biotech firm with limited cash reserves and significant ongoing clinical trial commitments. Investors should monitor the company's ability to secure additional financing, as the current liquidity profile appears insufficient to support long-term operational continuity.

Misapplication of Gross Margin Metrics

As evidenced by the 100% gross margin reported in several quarters, this metric is frequently misapplied to Nektar's business model, as it obscures the massive, sunk R&D costs that function as the true cost of goods sold for a platform-based biotechnology company.

Relying on gross margin to assess profitability is fundamentally flawed for this entity, as it ignores the recurring research expenses required to maintain the intellectual property. Analysts should instead focus on the operating margin and cash burn rate to gain a more accurate understanding of the company's true earning power.

Download Financial Ratios Data

Includes 30+ ratios · 30 years · Updated daily

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NKTR — Frequently Asked Questions

Quick answers to the most common questions about buying NKTR stock.

What is Nektar Therapeutics's P/E ratio?

Nektar Therapeutics's current P/E ratio is -7.7x. The historical average is 8.7x.

What is Nektar Therapeutics's ROE?

Nektar Therapeutics's return on equity (ROE) is -217.9%. The historical average is -81.5%.

Is NKTR stock overvalued?

Based on historical data, Nektar Therapeutics is trading at a P/E of -7.7x. Compare with industry peers and growth rates for a complete picture.

What are Nektar Therapeutics's profit margins?

Nektar Therapeutics has 100.0% gross margin and -236.8% operating margin.