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NGNENeurogene Inc.
$32.56$515M
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NGNE logoNeurogene Inc.(NGNE)Earnings, Financials & Key Ratios

NGNE•NASDAQ
$32.56
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCell and Gene Therapy Developers
AboutNeurogene Inc. develops life-changing genetic medicines for patients and their families affected by neurological diseases. Its product candidate includes NGN-401, an investigational AAV9 gene therapy for the treatment of Rett syndrome; and NGN-101 to treat neuronal ceroid lipofuscinosis subtype 5 batten disease. The company is headquartered in New York, New York.Show more
  • Revenue$0-100.0%
  • EBITDA-$103M-30.2%
  • Net Income-$90M-20.2%
  • EPS (Diluted)-4.24+0.9%
  • ROE-31.41%-3.8%

NGNE Price & Volume

Neurogene Inc. (NGNE) stock price & volume — 10-year historical chart

Loading chart...

Escalating Clinical Burn Challenges Capital Runway Sustainability

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Adequate
Cash Flow:Burning
Primary Risk:Clinical trial execution failure

Key Thesis Takeaways

  • Neurogene remains a high-risk, pre-revenue biotechnology entity heavily reliant on the successful clinical execution of its EXACT platform.
  • While the company maintains a cash position of $124.2 million as of 2026Q1, the persistent quarterly operating losses exceeding $20 million suggest that future dilutive financing may be required to reach pivotal data milestones.
  • Investors should monitor the company's ability to manage its $383.6 million accumulated deficit while navigating the capital-intensive requirements of its NGN-401 gene therapy program.

Verdict Logic

the company's current cash burn rate of $26.4 million per quarter relative to its $124.2 million cash balance suggests a limited runway that may necessitate further dilutive equity offerings.

NGNE Growth Metrics

Neurogene Inc. (NGNE) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-100%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-21.97%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-7.71%

Return on Capital

10 Years-34.2%
5 Years-39.26%
3 Years-34.46%
Last Year-34.82%

NGNE Recent Earnings

Neurogene Inc. (NGNE) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (67%)
Q2 2026Latest
May 12, 2026
Metric
Actual
Est
EPS
$1.39-7.2%
$1.30
Rev
—
—
Q2 2026
Mar 24, 2026
Metric
Actual
Est
EPS
$1.12+9.6%
$1.24
Rev
—
—
Q4 2025
Nov 13, 2025
Metric
Actual
Est
EPS
$0.99+21.4%
$1.26
Rev
—
—
Q3 2025
Aug 11, 2025
Metric
Actual
Est
EPS
$1.05+8.7%
$1.15
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 12, 2026
$1.39vs $1.30-7.2%
—
Q2 2026Mar 24, 2026
$1.12vs $1.24+9.6%
—
Q4 2025Nov 13, 2025
$0.99vs $1.26+21.4%
—
Q3 2025Aug 11, 2025
$1.05vs $1.15+8.7%
—
Based on last 12 quarters of dataView full earnings history →

Latest NGNE News

Recent stock market news and headlines for Neurogene Inc. (NGNE)

Business Wire·16h ago
Neurogene Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

NEW YORK--(BUSINESS WIRE)--Neurogene Inc. (Nasdaq: NGNE), a clinical-stage company founded to bring life-changing genetic medicines to patients and families affected by rare neurological diseases, today announced that the Compensation Committee of the Company's Board of Directors approved the grant of non-qualified stock options to purchase an aggregate of 96,450 shares of the Company's common stock to six new employees (the “Inducement Grants”) on July 6, 2026 (the “Grant Date”). The Inducemen.

Business Wire·6 days ago
Neurogene Inc. Announces Pricing of $125 Million Public Offering

NEW YORK--(BUSINESS WIRE)--Neurogene Inc. (Nasdaq: NGNE), a clinical-stage company founded to bring life-changing genetic medicines to patients and families affected by rare neurological diseases, today announced the pricing of its previously announced public offering of 3,500,000 shares of its common stock at a public offering price per share of $30.00 and, in lieu of common stock to certain investors, pre-funded warrants to purchase up to 666,666 shares of its common stock at a public offerin.

Business Wire·6 days ago
Neurogene Inc. Announces Proposed Public Offering

NEW YORK--(BUSINESS WIRE)--Neurogene Inc. (Nasdaq: NGNE), a clinical-stage company founded to bring life-changing genetic medicines to patients and families affected by rare neurological diseases, today announced that it has commenced a public offering of shares of its common stock or, in lieu of common stock to certain investors that so choose, pre-funded warrants to purchase shares of its common stock. In addition, Neurogene expects to grant the underwriters a 30-day option to purchase additi.

Seeking Alpha·Jun 29, 2026
Neurogene Inc. (NGNE) Discusses Updated Phase 1/2 Data for NGN-401 Gene Therapy in Rett Syndrome Transcript

Neurogene Inc. (NGNE) Discusses Updated Phase 1/2 Data for NGN-401 Gene Therapy in Rett Syndrome Transcript

GuruFocus·Jun 29, 2026
Neurogene Reports Positive Long-term Clinical Data from Phase 1/2 Trial of NGN-401 Gene Therapy for Rett Syndrome

Neurogene Inc. (Nasdaq: NGNE), a clinical-stage company founded to bring life-changing genetic medicines to patients and families affected by rare neurological

Peers Comparison

Key metrics vs top competitors for Neurogene Inc. (NGNE)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
NGNE logoNGNENeurogene Inc.Current
$32.56$514.51M-7.68-100%—-31.41%—
KRYS logoKRYSKrystal Biotech, Inc.
$374.68$11.05B54.7833.94%53.92%19.25%—
RCKT logoRCKTRocket Pharmaceuticals, Inc.
$3.99$435.68M-1.99——-70.79%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$313.50$9.06B-23.26-100%—-43.02%—
ARQT logoARQTArcutis Biotherapeutics, Inc.
$26.07$3.26B-200.5491.34%-0.57%-1.41%—
RARE logoRAREUltragenyx Pharmaceutical Inc.
$33.70$3.31B-5.7820.13%-91.03%——

Compare NGNE vs Peers

Neurogene Inc. (NGNE) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs KRYS

Most directly comparable listed peer for NGNE.

Scale Benchmark

vs ALNY

Larger-name benchmark to compare NGNE against a more recognizable public peer.

Peer Set

Compare Top 5

vs KRYS, RCKT, PRAX, ARQT

NGNE SEC Filings & Documents

Neurogene Inc. (NGNE) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 12, 2026·SEC

Material company update

Apr 20, 2026·SEC

Material company update

Mar 24, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 24, 2026·SEC

FY 2025

Mar 24, 2025·SEC

FY 2024

Mar 18, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 12, 2026·SEC

FY 2025

Nov 13, 2025·SEC

FY 2025

Aug 11, 2025·SEC

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NGNE Frequently Asked Questions

Neurogene Inc. (NGNE) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
How fast is Neurogene Inc. growing?

Neurogene Inc. (NGNE) saw revenue decline by 100.0% over the past year.

Is NGNE profitable?

Neurogene Inc. (NGNE) reported a net loss of $98.6M for fiscal year 2025.

Dividend & Returns
What is NGNE's return on equity?

Neurogene Inc. (NGNE) has a return on equity (ROE) of -31.4%. Negative ROE indicates the company is unprofitable.

What is Neurogene Inc.'s free cash flow?

Neurogene Inc. (NGNE) had negative free cash flow of $82.6M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in NGNE back in 2011?

Total return calculator · dividends reinvested · 15+ years of data

See returns →