Latest Ratios: P/E Ratio -2.1x · EV/EBITDA N/A · ROE -33.6%. (2019–2025 historical series)
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| Market Cap | $185M | $461M | $614M | $101M | $123M | $488M | — | — |
| Enterprise Value | $160M | $436M | $596M | $66M | $79M | $469M | — | — |
| P/E Ratio → | -2.07 | — | — | — | — | — | — | — |
| P/S Ratio | 9.69 | 24.15 | — | — | 8.21 | — | — | — |
| P/B Ratio | 0.60 | 1.62 | 3.01 | — | — | — | — | — |
| P/FCF | — | — | — | — | — | — | — | — |
| P/OCF | — | — | — | — | — | — | — | — |
P/E links to full P/E history page with 30-year chart
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 22.85 | — | — | 5.26 | — | — | — |
| EV / EBITDA | — | — | — | — | — | — | — | — |
| EV / EBIT | — | — | — | — | — | — | — | — |
| EV / FCF | — | — | — | — | — | — | — | — |
Margins and return-on-capital ratios measuring operating efficiency
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| Gross Margin | 96.3% | 96.3% | — | — | 100.0% | — | — | — |
| Operating Margin | -477.5% | -477.5% | — | — | -69.9% | — | — | — |
| Net Profit Margin | -430.3% | -430.3% | — | — | -72.1% | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| ROE | -33.6% | -33.6% | -89.4% | — | — | — | — | — |
| ROA | -31.5% | -31.5% | -34.8% | -119.3% | -33.1% | -346.0% | -605.9% | -1816.7% |
| ROIC | -30.7% | -30.7% | -152.1% | — | — | — | — | — |
| ROCE | -37.2% | -37.2% | -45.7% | -162.2% | -38.4% | -1591.0% | — | — |
Solvency and debt-coverage ratios — lower is generally safer
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.00 | 0.00 | 0.01 | — | — | — | — | — |
| Debt / EBITDA | — | — | — | — | — | — | — | 15.43 |
| Net Debt / Equity | — | -0.09 | -0.09 | — | — | — | — | — |
| Net Debt / EBITDA | — | — | — | — | — | — | — | 15.39 |
| Debt / FCF | — | — | — | — | — | — | — | — |
| Interest Coverage | — | — | — | — | — | — | -1708.33 | -0.36 |
Net cash position: cash ($25M) exceeds total debt ($350000)
Short-term solvency ratios and asset-utilisation metrics
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 13.80 | 13.80 | 20.36 | 3.63 | 4.91 | 14.62 | 0.66 | 0.00 |
| Quick Ratio | 13.80 | 13.80 | 20.36 | 3.63 | 4.91 | 14.62 | 0.66 | 0.00 |
| Cash Ratio | 13.80 | 13.80 | 20.09 | 3.55 | 4.68 | 14.61 | 0.62 | 0.00 |
| Asset Turnover | — | 0.06 | — | — | 0.32 | — | — | — |
| Inventory Turnover | — | — | — | — | — | — | — | — |
| Days Sales Outstanding | — | 46.45 | — | — | — | — | — | — |
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| Earnings Yield | — | — | — | — | — | — | — | — |
| FCF Yield | — | — | — | — | — | — | — | — |
| Buyback Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.1% | 0.0% | — | — |
| Total Shareholder Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.1% | 0.0% | — | — |
| Shares Outstanding | — | $29M | $21M | $8M | $8M | $8M | $8M | $8M |
Binary Clinical Regulatory Outcome
As reported in financial data, LENZ trades at a price-to-sales ratio of 9.56, a metric that appears largely disconnected from fundamental performance given the company's lack of recurring commercial revenue and its reliance on non-recurring milestone payments to support its current market capitalization.
The elevated P/S multiple suggests that investors are pricing in a high probability of successful FDA approval for the LNZ100/101 pipeline rather than current operational output. This valuation approach warrants caution, as any delay in the regulatory pathway could lead to a significant compression of multiples as the market re-evaluates the firm's long-term commercial viability.
Based on recent quarterly filings, LENZ's ROIC has consistently trended in negative territory, reaching -13.8% in 2026Q1, which reflects the ongoing destruction of shareholder capital as the firm prioritizes high-cost clinical development over the generation of positive returns on its invested capital base.
The persistent negative ROIC is a structural feature of the company's current development-stage business model, where massive R&D and SG&A outlays are not yet offset by product-driven margins. Investors should monitor whether the company can achieve a positive inflection in capital returns once commercialization begins, or if the cost of market entry will continue to suppress profitability.
According to the provided financial statements, the company's cash conversion cycle remains highly volatile, with a negative 241-day cycle in 2026Q1, indicating that the firm is currently operating without the benefit of a standard commercial working capital cycle to support its liquidity needs.
The extreme fluctuations in days payable outstanding and inventory metrics suggest that the company is managing its cash outflows primarily to extend its operational runway rather than optimizing for operational efficiency. This lack of a stable working capital cycle is typical for pre-revenue biotech firms but highlights the extreme sensitivity of the balance sheet to vendor payment timing.
As indicated by the reported current ratio of 10.40 in 2026Q1, LENZ maintains a high liquidity position on paper, yet this figure appears misleading when contrasted against the company's substantial quarterly operating burn rate and the absence of sustainable, recurring cash inflows from product sales.
While the current ratio suggests an ability to cover short-term obligations, the rapid depletion of cash reserves indicates that the company's liquidity position is highly vulnerable to any unforeseen regulatory setbacks. The reliance on external financing to maintain this liquidity buffer suggests that the firm remains in a precarious position until it can achieve commercial scale.
The most commonly misapplied metric for LENZ is the price-to-sales ratio, which obscures the fact that the company's current revenue is derived from non-recurring milestones rather than sustainable product sales, rendering traditional valuation comparisons to commercial-stage pharmaceutical peers fundamentally flawed and potentially misleading for investors.
Analysts should instead focus on the 'burn-to-approval' ratio or the cash runway relative to clinical milestones, as these metrics provide a more accurate assessment of the company's financial health. Relying on revenue-based multiples in a pre-commercial context risks overestimating the company's current market value by ignoring the significant execution and regulatory risks that remain ahead.
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Quick answers to the most common questions about buying LENZ stock.
LENZ Therapeutics, Inc.'s current P/E ratio is -2.1x. This places it at the 50th percentile of its historical range.
LENZ Therapeutics, Inc.'s return on equity (ROE) is -33.6%. The historical average is -61.5%.
Based on historical data, LENZ Therapeutics, Inc. is trading at a P/E of -2.1x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
LENZ Therapeutics, Inc. has 96.3% gross margin and -477.5% operating margin.