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LENZLENZ Therapeutics, Inc.
$5.90$185M
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  4. Financial Ratios

LENZ Therapeutics, Inc. (LENZ) Financial Ratios

Latest Ratios: P/E Ratio -2.1x · EV/EBITDA N/A · ROE -33.6%. (2019–2025 historical series)

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly

LENZ Valuation Multiples

Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019
Market Cap$185M$461M$614M$101M$123M$488M——
Enterprise Value$160M$436M$596M$66M$79M$469M——
P/E Ratio →-2.07———————
P/S Ratio9.6924.15——8.21———
P/B Ratio0.601.623.01—————
P/FCF————————
P/OCF————————

P/E links to full P/E history page with 30-year chart

LENZ EV Ratios

Enterprise-value multiples — capital-structure-neutral measures of total business value

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019
EV / Revenue—22.85——5.26———
EV / EBITDA————————
EV / EBIT————————
EV / FCF————————

LENZ Profitability

Margins and return-on-capital ratios measuring operating efficiency

Margins

Full margin charts and quarterly trend are on the Earnings History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019
Gross Margin96.3%96.3%——100.0%———
Operating Margin-477.5%-477.5%——-69.9%———
Net Profit Margin-430.3%-430.3%——-72.1%———

Return on Capital

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019
ROE-33.6%-33.6%-89.4%—————
ROA-31.5%-31.5%-34.8%-119.3%-33.1%-346.0%-605.9%-1816.7%
ROIC-30.7%-30.7%-152.1%—————
ROCE-37.2%-37.2%-45.7%-162.2%-38.4%-1591.0%——

LENZ Leverage & Debt

Solvency and debt-coverage ratios — lower is generally safer

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019
Debt / Equity0.000.000.01—————
Debt / EBITDA———————15.43
Net Debt / Equity—-0.09-0.09—————
Net Debt / EBITDA———————15.39
Debt / FCF————————
Interest Coverage——————-1708.33-0.36

Net cash position: cash ($25M) exceeds total debt ($350000)

LENZ Liquidity & Efficiency

Short-term solvency ratios and asset-utilisation metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019
Current Ratio13.8013.8020.363.634.9114.620.660.00
Quick Ratio13.8013.8020.363.634.9114.620.660.00
Cash Ratio13.8013.8020.093.554.6814.610.620.00
Asset Turnover—0.06——0.32———
Inventory Turnover————————
Days Sales Outstanding—46.45——————

LENZ Shareholder Yields

Earnings, FCF, buyback, and dividend yields — total returns to shareholders

Dividends

Full dividend history and growth charts are on the Dividend History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019
Dividend Yield————————
Payout Ratio————————

Total Shareholder Return Metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019
Earnings Yield————————
FCF Yield————————
Buyback Yield0.0%0.0%0.0%0.0%0.1%0.0%——
Total Shareholder Yield0.0%0.0%0.0%0.0%0.1%0.0%——
Shares Outstanding—$29M$21M$8M$8M$8M$8M$8M

Key Metrics

Growth RegimeMixed
ProfitabilityNegative
Balance SheetVulnerable
Cash FlowBurning
Top Statement Risk

Binary Clinical Regulatory Outcome

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2026Q1)

Speculative Valuation Amid Clinical Uncertainty

As reported in financial data, LENZ trades at a price-to-sales ratio of 9.56, a metric that appears largely disconnected from fundamental performance given the company's lack of recurring commercial revenue and its reliance on non-recurring milestone payments to support its current market capitalization.

The elevated P/S multiple suggests that investors are pricing in a high probability of successful FDA approval for the LNZ100/101 pipeline rather than current operational output. This valuation approach warrants caution, as any delay in the regulatory pathway could lead to a significant compression of multiples as the market re-evaluates the firm's long-term commercial viability.

Capital Erosion Through Clinical Investment

Based on recent quarterly filings, LENZ's ROIC has consistently trended in negative territory, reaching -13.8% in 2026Q1, which reflects the ongoing destruction of shareholder capital as the firm prioritizes high-cost clinical development over the generation of positive returns on its invested capital base.

The persistent negative ROIC is a structural feature of the company's current development-stage business model, where massive R&D and SG&A outlays are not yet offset by product-driven margins. Investors should monitor whether the company can achieve a positive inflection in capital returns once commercialization begins, or if the cost of market entry will continue to suppress profitability.

Working Capital Inefficiency and Burn

According to the provided financial statements, the company's cash conversion cycle remains highly volatile, with a negative 241-day cycle in 2026Q1, indicating that the firm is currently operating without the benefit of a standard commercial working capital cycle to support its liquidity needs.

The extreme fluctuations in days payable outstanding and inventory metrics suggest that the company is managing its cash outflows primarily to extend its operational runway rather than optimizing for operational efficiency. This lack of a stable working capital cycle is typical for pre-revenue biotech firms but highlights the extreme sensitivity of the balance sheet to vendor payment timing.

Liquidity Buffer Facing Severe Pressure

As indicated by the reported current ratio of 10.40 in 2026Q1, LENZ maintains a high liquidity position on paper, yet this figure appears misleading when contrasted against the company's substantial quarterly operating burn rate and the absence of sustainable, recurring cash inflows from product sales.

While the current ratio suggests an ability to cover short-term obligations, the rapid depletion of cash reserves indicates that the company's liquidity position is highly vulnerable to any unforeseen regulatory setbacks. The reliance on external financing to maintain this liquidity buffer suggests that the firm remains in a precarious position until it can achieve commercial scale.

Misapplication of Traditional Revenue Multiples

The most commonly misapplied metric for LENZ is the price-to-sales ratio, which obscures the fact that the company's current revenue is derived from non-recurring milestones rather than sustainable product sales, rendering traditional valuation comparisons to commercial-stage pharmaceutical peers fundamentally flawed and potentially misleading for investors.

Analysts should instead focus on the 'burn-to-approval' ratio or the cash runway relative to clinical milestones, as these metrics provide a more accurate assessment of the company's financial health. Relying on revenue-based multiples in a pre-commercial context risks overestimating the company's current market value by ignoring the significant execution and regulatory risks that remain ahead.

Download Financial Ratios Data

Includes 30+ ratios · 7 years · Updated daily

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LENZ — Frequently Asked Questions

Quick answers to the most common questions about buying LENZ stock.

What is LENZ Therapeutics, Inc.'s P/E ratio?

LENZ Therapeutics, Inc.'s current P/E ratio is -2.1x. This places it at the 50th percentile of its historical range.

What is LENZ Therapeutics, Inc.'s ROE?

LENZ Therapeutics, Inc.'s return on equity (ROE) is -33.6%. The historical average is -61.5%.

Is LENZ stock overvalued?

Based on historical data, LENZ Therapeutics, Inc. is trading at a P/E of -2.1x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.

What are LENZ Therapeutics, Inc.'s profit margins?

LENZ Therapeutics, Inc. has 96.3% gross margin and -477.5% operating margin.