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ICUSeaStar Medical Holding Corporation
$5.07$199M
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ICU logoSeaStar Medical Holding Corporation(ICU)Earnings, Financials & Key Ratios

ICU•NASDAQ
$5.07
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryImmunology and Inflammation Therapies
AboutSeaStar Medical Holding Corporation, a medical device company, focuses on providing novel solutions and services to treat hyperinflammation and cytokine storm in critically ill patients. The company is developing and commercializing extracorporeal therapies that target the effector cells that drive systemic inflammation, causing direct tissue damage and secreting a range of pro-inflammatory cytokines that initiate and propagate imbalanced immune responses. It is developing products in various therapeutic areas, including pediatric and adult acute kidney injury on CRRT; cardiorenal syndrome in congestive heart failure with and without LVAD; myocardial stunning in end stage renal disease; and hepatorenal syndrome. The company is based in Denver, Colorado.Show more
  • Revenue$1M+814.1%
  • EBITDA-$12M+50.5%
  • Net Income-$12M+51.1%
  • EPS (Diluted)-5.86+91.2%
  • Gross Margin95.7%-4.3%
  • EBITDA Margin-986.63%+94.6%
  • Operating Margin-986.63%+92.5%
  • Net Margin-984.6%+94.6%
  • ROE-295.15%

ICU Price & Volume

SeaStar Medical Holding Corporation (ICU) stock price & volume — 10-year historical chart

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High Gross Margins Mask Persistent Operational Losses

Investment Thesis • Updated 2026Q1

VerdictNeutral
Growth:Expanding
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical trial funding dependency

Key Thesis Takeaways

  • SeaStar Medical is currently navigating a critical transition from research-stage development to commercial scaling, evidenced by a 68.9% year-over-year revenue growth in 2026Q1.
  • While the company maintains a robust 90.7% gross margin, the business model remains heavily dependent on external equity financing to offset recurring quarterly operating losses of $3.6M.
  • Investors should monitor the progress of the NEUTRALIZE-AKI clinical trial, as the company's long-term viability hinges on successful regulatory milestones to mitigate its $155.2M accumulated deficit.

Verdict Logic

while the company shows early revenue growth, the $9.3M cash balance against persistent quarterly operating losses of $3.6M suggests significant execution risk and potential for further shareholder dilution.

ICU Growth Metrics

SeaStar Medical Holding Corporation (ICU) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM235.51%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM25.19%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM88.17%

Return on Capital

10 Years-324.29%
5 Years-295.76%
3 Years-295.76%
Last Year-295.76%

ICU Recent Earnings

SeaStar Medical Holding Corporation (ICU) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)●Beat Revenue 4/12 qtrs (57%)
Q2 2026Latest
May 13, 2026
Metric
Actual
Est
EPS
$0.90-23.3%
$0.73
Rev
$495,000+13.1%
$437,500
Q2 2026
Mar 25, 2026
Metric
Actual
Est
EPS
$0.80+17.5%
$0.97
Rev
$420,000+88.8%
$222,500
Q4 2025
Nov 13, 2025
Metric
Actual
Est
EPS
$1.30+13.3%
$1.50
Rev
$183,000-26.8%
$250,000
Q3 2025
Aug 13, 2025
Metric
Actual
Est
EPS
$0.18+58.1%
$0.43
Rev
$338,000+38.0%
$245,000
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 13, 2026
$0.90vs $0.73-23.3%
$495,000vs $437,500+13.1%
Q2 2026Mar 25, 2026
$0.80vs $0.97+17.5%
$420,000vs $222,500+88.8%
Q4 2025Nov 13, 2025
$1.30vs $1.50+13.3%
$183,000vs $250,000-26.8%
Q3 2025Aug 13, 2025
$0.18vs $0.43+58.1%
$338,000vs $245,000+38.0%
Based on last 12 quarters of dataView full earnings history →

Latest ICU News

Recent stock market news and headlines for SeaStar Medical Holding Corporation (ICU)

GlobeNewsWire·Jun 23, 2026
SeaStar Medical Announces New ICD-10-PCS Codes for Its SCD Therapy for Acute Kidney Injury

Enables standardized inpatient hospital billing for QUELIMMUNE ® (SCD-PED) therapy

GlobeNewsWire·Jun 22, 2026
SeaStar Medical to Present at Upcoming Investor Summit Conference

DENVER, June 22, 2026 (GLOBE NEWSWIRE) -- SeaStar Medical Holding Corporation (Nasdaq: ICU), a commercial-stage healthcare company focused on transformational treatments for critically ill patients facing organ failure and potential loss of life, announced today that Eric Schlorff, Chief Executive Officer of SeaStar Medical, will present at the Virtual Investor Summit Conference on Wednesday, June 24th at 10:30 am Eastern Time.

Peers Comparison

Key metrics vs top competitors for SeaStar Medical Holding Corporation (ICU)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
ICU logoICUSeaStar Medical Holding CorporationCurrent
$5.07$198.66M-0.87814.07%-984.6%-295.15%—
NKTR logoNKTRNektar Therapeutics
$74.90$1.46B-7.70-43.89%-284.18%-87%—
TPVG logoTPVGTriplePoint Venture Growth BDC Corp.
$4.75$192.85M3.8936.55%-19.55%-3.39%—
AKBA logoAKBAAkebia Therapeutics, Inc.
$1.36$364.83M-65.3847.46%-8.83%-62.72%—
CPRX logoCPRXCatalyst Pharmaceuticals, Inc.
$31.49$3.85B18.7419.78%37.08%23.65%—
XOMA logoXOMAXOMA Royalty Corp.
$43.89$550.42M30.0683.06%86.97%30.21%—

Compare ICU vs Peers

SeaStar Medical Holding Corporation (ICU) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs NKTR

Most directly comparable listed peer for ICU.

Scale Benchmark

vs STE

Larger-name benchmark to compare ICU against a more recognizable public peer.

Peer Set

Compare Top 5

vs NKTR, TPVG, AKBA, CPRX

ICU SEC Filings & Documents

SeaStar Medical Holding Corporation (ICU) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 13, 2026·SEC

Material company update

Apr 28, 2026·SEC

Material company update

Mar 25, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 25, 2026·SEC

FY 2025

Mar 27, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

May 13, 2026·SEC

FY 2025

Nov 13, 2025·SEC

FY 2025

Aug 13, 2025·SEC

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ICU Frequently Asked Questions

SeaStar Medical Holding Corporation (ICU) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is SeaStar Medical Holding Corporation's revenue?

SeaStar Medical Holding Corporation (ICU) reported $1.4M in revenue for fiscal year 2025.

How fast is SeaStar Medical Holding Corporation growing?

SeaStar Medical Holding Corporation (ICU) grew revenue by 814.1% over the past year. This is strong growth.

Is ICU profitable?

SeaStar Medical Holding Corporation (ICU) reported a net loss of $11.9M for fiscal year 2025.

Dividend & Returns
What is ICU's return on equity?

SeaStar Medical Holding Corporation (ICU) has a return on equity (ROE) of -295.2%. Negative ROE indicates the company is unprofitable.

What is SeaStar Medical Holding Corporation's free cash flow?

SeaStar Medical Holding Corporation (ICU) had negative free cash flow of $13.7M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in ICU back in 2020?

Total return calculator · dividends reinvested · 6+ years of data

See returns →