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AKBAAkebia Therapeutics, Inc.
$1.36$365M
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AKBA logoAkebia Therapeutics, Inc.(AKBA)Earnings, Financials & Key Ratios

AKBA•NASDAQ
$1.36
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Specialty Pharma
AboutAkebia Therapeutics, Inc., a biopharmaceutical company, focuses on the development and commercialization of therapeutics for patients with kidney diseases. The company's lead product investigational product candidate is vadadustat, an oral therapy, which is in Phase III development for the treatment of anemia due to chronic kidney disease (CKD) in dialysis-dependent and non-dialysis dependent adult patients. It also offers Auryxia, a ferric citrate that is used to control the serum phosphorus levels in adult patients with DD-CKD on dialysis; and the treatment of iron deficiency anemia in adult patients with CKD not on dialysis. Akebia Therapeutics, Inc. has collaboration agreements with Otsuka Pharmaceutical Co. Ltd. for the development and commercialization of vadadustat in the United States, the European Union, Russia, China, Australia, Canada, the Middle East, and other countries; and Mitsubishi Tanabe Pharma Corporation for the development and commercialization of vadadustat in Japan and other Asian countries, as well as research and license agreement with Janssen Pharmaceutica NV for the development and commercialization of hypoxia-inducible factor prolyl hydroxylase targeted compounds worldwide. The company was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.Show more
  • Revenue$236M+47.5%
  • EBITDA$25M+291.0%
  • Net Income-$5M+92.3%
  • EPS (Diluted)-0.02+93.7%
  • Gross Margin83.29%+37.5%
  • EBITDA Margin10.49%+229.5%
  • Operating Margin9.95%+131.6%
  • Net Margin-2.26%+94.8%
  • ROE-16.39%

AKBA Price & Volume

Akebia Therapeutics, Inc. (AKBA) stock price & volume — 10-year historical chart

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Vafseo Commercial Launch Faces Significant Profitability Headwinds

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Strained
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Commercial adoption and reimbursement

Key Thesis Takeaways

  • Akebia Therapeutics faces a challenging transition as it attempts to scale the commercial launch of Vafseo within a highly competitive dialysis market.
  • While the company achieved brief profitability in mid-2025, the return to a $9.1 million net loss in 2026Q1 suggests that operating expenses are not scaling efficiently with revenue.
  • Investors should remain cautious regarding the company's ability to maintain a sustainable cash runway given the volatility in free cash flow and the persistent drag of stock-based compensation.

Verdict Logic

the company's inability to sustain profitability, coupled with a rapid depletion of cash reserves from $184.8 million in 2025Q4 to $162.6 million in 2026Q1, presents significant execution risk.

AKBA Growth Metrics

Akebia Therapeutics, Inc. (AKBA) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-4.33%
3 Years-6.88%
TTM25.68%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM54.73%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM63.29%

Return on Capital

10 Years-43.45%
5 Years-30.65%
3 Years-15.89%
Last Year13.3%

AKBA Recent Earnings

Akebia Therapeutics, Inc. (AKBA) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)●Beat Revenue 7/12 qtrs (58%)
Q2 2026Latest
May 7, 2026
Metric
Actual
Est
EPS
$0.03-200.0%
$0.01
Rev
$54M+3.6%
$52M
Q1 2026
Feb 26, 2026
Metric
Actual
Est
EPS
$0.05-66.7%
$0.03
Rev
$58M+25.0%
$46M
Q4 2025
Nov 10, 2025
Metric
Actual
Est
EPS
$0.00+103.3%
$0.06
Rev
$59M+21.5%
$48M
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.00+104.6%
$0.02
Rev
$62M+30.5%
$48M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$0.03vs $0.01-200.0%
$54Mvs $52M+3.6%
Q1 2026Feb 26, 2026
$0.05vs $0.03-66.7%
$58Mvs $46M+25.0%
Q4 2025Nov 10, 2025
$0.00vs $0.06+103.3%
$59Mvs $48M+21.5%
Q3 2025Aug 7, 2025
$0.00vs $0.02+104.6%
$62Mvs $48M+30.5%
Based on last 12 quarters of dataView full earnings history →

Latest AKBA News

Recent stock market news and headlines for Akebia Therapeutics, Inc. (AKBA)

GlobeNewsWire·5 days ago
Akebia Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

CAMBRIDGE, Mass., July 02, 2026 (GLOBE NEWSWIRE) -- Akebia Therapeutics®, Inc. (Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease, granted 3 newly-hired employees options to purchase an aggregate of 125,600 shares of Akebia's common stock on June 30, 2026. The options were granted as an inducement material to each employee entering into employment with Akebia. The options were granted in accordance with Nasdaq Listing Rule 5635(c)(4).

GlobeNewsWire·Jun 30, 2026
U.S. Renal Care and Akebia Announce Interim Analysis of VOICE Trial Demonstrated Overwhelming Statistical Evidence of Improved Safety Outcomes for Patients Treated with Vafseo versus an ESA

Vafseo® demonstrated a clinically meaningful safety outcome benefit in U.S. patients with anemia due to CKD on dialysis utilizing TIW dosing regimen Primary Investigator to stop trial on recommendation from Independent Data Monitoring Committee and Trial Steering Committee Interim analysis on primary endpoint replicated safety outcomes reported in the recently published win odds analysis of the INNO 2 VATE clinical trial program Akebia and USRC expect to submit data for presentation at an upcoming scientific meeting CAMBRIDGE, Mass., June 30, 2026 (GLOBE NEWSWIRE) -- Akebia Therapeutics®, Inc. (Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease, and U.S. Renal Care (USRC), the nation's largest privately held and fastest-growing kidney care provider, are pleased to announce today the decision by USRC Kidney Research to stop the Vafseo Outcomes In Center Experience (VOICE) trial following a planned interim analysis.

Peers Comparison

Key metrics vs top competitors for Akebia Therapeutics, Inc. (AKBA)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
AKBA logoAKBAAkebia Therapeutics, Inc.Current
$1.36$364.83M-65.3847.46%-2.26%-16.39%—
FOLD logoFOLDAmicus Therapeutics, Inc.
$14.49$4.55B-164.8520.05%-4.27%-12.02%—
PTGX logoPTGXProtagonist Therapeutics, Inc.
$140.85$9.06B-68.71-89.41%-648.27%-17.76%—
CYCN logoCYCNCyclerion Therapeutics, Inc.
$3.48$15.07M-3.193.7%-264.73%-62.1%—
ANIP logoANIPANI Pharmaceuticals, Inc.
$85.99$1.95B25.9043.78%9.71%17.32%—
HALO logoHALOHalozyme Therapeutics, Inc.
$81.57$9.68B31.8637.55%23.13%126.27%—

Compare AKBA vs Peers

Akebia Therapeutics, Inc. (AKBA) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs FOLD

Most directly comparable listed peer for AKBA.

Scale Benchmark

vs AMGN

Larger-name benchmark to compare AKBA against a more recognizable public peer.

Peer Set

Compare Top 5

vs FOLD, PTGX, CYCN, ANIP

AKBA SEC Filings & Documents

Akebia Therapeutics, Inc. (AKBA) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 7, 2026·SEC

Material company update

Apr 1, 2026·SEC

Material company update

Feb 26, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 26, 2026·SEC

FY 2025

Mar 13, 2025·SEC

FY 2024

Mar 14, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 10, 2025·SEC

FY 2025

Aug 7, 2025·SEC

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AKBA Frequently Asked Questions

Akebia Therapeutics, Inc. (AKBA) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Akebia Therapeutics, Inc.'s revenue?

Akebia Therapeutics, Inc. (AKBA) reported $232.4M in revenue for fiscal year 2025.

How fast is Akebia Therapeutics, Inc. growing?

Akebia Therapeutics, Inc. (AKBA) grew revenue by 47.5% over the past year. This is strong growth.

Is AKBA profitable?

Akebia Therapeutics, Inc. (AKBA) reported a net loss of $20.5M for fiscal year 2025.

Dividend & Returns
What is AKBA's return on equity?

Akebia Therapeutics, Inc. (AKBA) has a return on equity (ROE) of -16.4%. Negative ROE indicates the company is unprofitable.

What is Akebia Therapeutics, Inc.'s free cash flow?

Akebia Therapeutics, Inc. (AKBA) generated $60.0M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

What if you invested $1,000 in AKBA back in 2012?

Total return calculator · dividends reinvested · 14+ years of data

See returns →