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GANXGain Therapeutics, Inc.
$1.81$77M
Overview & Verdict
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GANX logoGain Therapeutics, Inc.(GANX)Earnings, Financials & Key Ratios

GANX•NASDAQ
$1.81
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutGain Therapeutics, Inc., a biotechnology company, engages in developing various therapies to treat diseases caused by protein misfolding. It focuses on rare genetic diseases and neurological disorders. The company uses its Site-Directed Enzyme Enhancement Therapy platform to discover allosteric sites on misfolded proteins and identify proprietary small molecules that bind these sites, restore protein folding, and treat disease. It is developing structurally targeted allosteric regulator candidates to treat various diseases, including Morquio B, GM1 gangliosidosis (GM1), neuronopathic Gaucher disease, GBA1 Parkinson's, Krabbe, and Mucopolysaccharidosis type 1 diseases. The company was founded in 2017 and is based in Bethesda, Maryland.Show more
  • Revenue$0
  • EBITDA-$19M+8.1%
  • Net Income-$20M+1.2%
  • EPS (Diluted)-0.61+31.5%
  • ROE-155.66%+24.1%

GANX Price & Volume

Gain Therapeutics, Inc. (GANX) stock price & volume — 10-year historical chart

Loading chart...

Persistent Clinical Burn Challenges Capital Runway Sustainability

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical trial funding shortfall

Key Thesis Takeaways

  • Gain Therapeutics remains a pre-revenue, development-stage biotechnology firm whose valuation is entirely contingent on the successful validation of its SEE-Tx platform.
  • While the company maintains a low debt-to-equity ratio of 0.04, the persistent quarterly operating losses, which reached $5.4 million in 2026Q1, necessitate ongoing reliance on external financing.
  • Investors should monitor the company's ability to extend its $20.8 million cash position from 2025Q4, as the lack of commercial revenue streams creates significant dilution risk for existing shareholders.

Verdict Logic

the company's inability to generate revenue against a $101.4 million accumulated deficit in retained earnings suggests that the current $20.8 million cash position may be insufficient to support long-term clinical development without further dilutive events.

GANX Growth Metrics

Gain Therapeutics, Inc. (GANX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-1.49%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM34.83%

Return on Capital

10 Years-975.88%
5 Years-115.92%
3 Years-151.2%
Last Year-135.2%

GANX Recent Earnings

Gain Therapeutics, Inc. (GANX) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)●Beat Revenue 0/12 qtrs (0%)
Q2 2026Latest
May 11, 2026
Metric
Actual
Est
EPS
$0.13+0.0%
$0.13
Rev
—
$33,333
Q2 2026
Mar 26, 2026
Metric
Actual
Est
EPS
$0.11+21.4%
$0.14
Rev
—
$25,000
Q4 2025
Nov 12, 2025
Metric
Actual
Est
EPS
$0.15+0.0%
$0.15
Rev
—
—
Q3 2025
Aug 12, 2025
Metric
Actual
Est
EPS
$0.19-11.8%
$0.17
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 11, 2026
$0.13vs $0.13+0.0%
—vs $33,333
Q2 2026Mar 26, 2026
$0.11vs $0.14+21.4%
—vs $25,000
Q4 2025Nov 12, 2025
$0.15vs $0.15+0.0%
—
Q3 2025Aug 12, 2025
$0.19vs $0.17-11.8%
—
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Gain Therapeutics, Inc. (GANX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
GANX logoGANXGain Therapeutics, Inc.Current
$1.81$77.2M-2.97——-155.66%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$313.50$9.06B-23.26-100%—-43.02%—
ACMR logoACMRACM Research, Inc.
$98.52$6.52B71.9115.24%9.48%5.13%—
RARE logoRAREUltragenyx Pharmaceutical Inc.
$33.70$3.31B-5.7820.13%-91.03%——
FOLD logoFOLDAmicus Therapeutics, Inc.
$14.49$4.55B-164.8520.05%-4.27%-12.02%—
LGND logoLGNDLigand Pharmaceuticals Incorporated
$320.42$6.42B52.2760.4%55.95%16.19%—

Compare GANX vs Peers

Gain Therapeutics, Inc. (GANX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PRAX

Most directly comparable listed peer for GANX.

Scale Benchmark

vs TMO

Larger-name benchmark to compare GANX against a more recognizable public peer.

Peer Set

Compare Top 5

vs PRAX, ACMR, RARE, FOLD

GANX SEC Filings & Documents

Gain Therapeutics, Inc. (GANX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 26, 2026·SEC

Material company update

May 11, 2026·SEC

Material company update

Mar 26, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 26, 2026·SEC

FY 2025

Mar 27, 2025·SEC

FY 2024

Mar 26, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 11, 2026·SEC

FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 12, 2025·SEC

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GANX Frequently Asked Questions

Gain Therapeutics, Inc. (GANX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is GANX profitable?

Gain Therapeutics, Inc. (GANX) reported a net loss of $21.2M for fiscal year 2025.

Dividend & Returns
What is GANX's return on equity?

Gain Therapeutics, Inc. (GANX) has a return on equity (ROE) of -155.7%. Negative ROE indicates the company is unprofitable.

What is Gain Therapeutics, Inc.'s free cash flow?

Gain Therapeutics, Inc. (GANX) had negative free cash flow of $19.4M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in GANX back in 2018?

Total return calculator · dividends reinvested · 8+ years of data

See returns →