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EXASExact Sciences Corporation
$104.91$20.0B
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EXAS logoExact Sciences Corporation(EXAS)Earnings, Financials & Key Ratios

EXAS•NASDAQ
$104.91
Price updated Jun 20, 2026
SectorHealthcareIndustryDiagnostics & ResearchSub-IndustryMolecular and Genetic Diagnostics
AboutExact Sciences Corporation provides cancer screening and diagnostic test products in the United States and internationally. The company offers Cologuard, a non-invasive stool-based DNA screening test to detect DNA and hemoglobin biomarkers associated with colorectal cancer and pre-cancer. It also provides Oncotype DX, a gene expression tests for breast, prostate, and colon cancers; Oncotype Test, a tissue test delivering tumor profiling to aid therapy selection for patients with advanced, metastatic, refractory, or recurrent cancer; Oncotype DX AR-V7 Nucleus Detect Test, a liquid-based test for advanced stage prostate cancer; Oncomap ExTra, that provides a complete biological picture of certain refractory, rare, or aggressive cancers; and Covid-19 testing services. The company's pipeline products focus on enhancing the Cologuard test's performance characteristics and developing blood and other fluid-based tests. It has license agreements with MAYO Foundation for Medical Education and Research; and Hologic, Inc. Exact Sciences Corporation was incorporated in 1995 and is headquartered in Madison, Wisconsin.Show more
  • Revenue$3.25B+17.7%
  • EBITDA-$206M+75.3%
  • Net Income-$208M+79.8%
  • EPS (Diluted)-1.10+80.3%
  • Gross Margin69.69%+0.2%
  • EBITDA Margin-6.35%+79.0%
  • Operating Margin-6.35%+83.3%
  • Net Margin-6.4%+82.8%
  • ROE-8.66%+76.7%

EXAS Price & Volume

Exact Sciences Corporation (EXAS) stock price & volume — 10-year historical chart

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Accelerating Revenue Growth Faces Persistent Operating Losses

Investment Thesis • Updated 2025Q4

VerdictNeutral
Growth:Accelerating
Profitability:Strained
Financial:Strained
Cash Flow:Improving
Primary Risk:Regulatory reimbursement and competition

Key Thesis Takeaways

  • Exact Sciences is demonstrating significant top-line momentum with 23.1% year-over-year revenue growth in 2025Q4, yet the firm remains challenged by a persistent inability to achieve operating leverage as SG&A expenses continue to outpace gross profit.
  • While the company has successfully transitioned to positive free cash flow of $120.4 million in the most recent quarter, the reliance on $2.5 billion in total debt and a $4.7 billion accumulated deficit necessitates a cautious outlook.
  • Investors should monitor whether the firm can sustain this cash-generating inflection point without further diluting shareholder equity or increasing its already substantial $2.4 billion goodwill-heavy asset base.

Verdict Logic

while the company achieved a 13.7% FCF margin in 2025Q4, the persistent net loss of $86.0 million and high debt-to-equity ratio of 1.05 warrant further evidence of sustainable operational profitability.

EXAS Growth Metrics

Exact Sciences Corporation (EXAS) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years55.44%
5 Years16.84%
3 Years15.92%
TTM17.69%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM79.79%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM80.3%

Return on Capital

10 Years-17.61%
5 Years-10.54%
3 Years-8.81%
Last Year-3.96%

EXAS Recent Earnings

Exact Sciences Corporation (EXAS) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 9/12 qtrs (75%)●Beat Revenue 11/12 qtrs (92%)
Q1 2026Latest
Feb 13, 2026
Metric
Actual
Est
EPS
$0.45-316.9%
$0.11
Rev
$878M+2.0%
$861M
Q4 2025
Nov 3, 2025
Metric
Actual
Est
EPS
$0.24+492.0%
$0.06
Rev
$851M+5.0%
$811M
Q3 2025
Aug 6, 2025
Metric
Actual
Est
EPS
$0.22+1200.0%
$0.02
Rev
$811M+0.1%
$810M
Q2 2025
May 1, 2025
Metric
Actual
Est
EPS
$0.21+43.2%
$0.37
Rev
$707M+2.6%
$689M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q1 2026LatestFeb 13, 2026
$0.45vs $0.11-316.9%
$878Mvs $861M+2.0%
Q4 2025Nov 3, 2025
$0.24vs $0.06+492.0%
$851Mvs $811M+5.0%
Q3 2025Aug 6, 2025
$0.22vs $0.02+1200.0%
$811Mvs $810M+0.1%
Q2 2025May 1, 2025
$0.21vs $0.37+43.2%
$707Mvs $689M+2.6%
Based on last 12 quarters of dataView full earnings history →

Latest EXAS News

Recent stock market news and headlines for Exact Sciences Corporation (EXAS)

Seeking Alpha·4 days ago
Abbott Laboratories Q2 Earnings Preview: A Contrarian Buy Opportunity Worth Considering

Abbott Laboratories is upgraded to Buy ahead of Q2 2026 earnings, following a challenging period marked by share price underperformance. The recent acquisition of Exact Sciences adds a high-growth cancer diagnostics vertical, targeting $3bn incremental 2026 sales and potential long-term revenue expansion. 2026 guidance projects 6.5–7.5% organic sales growth and $5.38–$5.58 adjusted EPS, with Exact Sciences acquisition causing $0.20 EPS dilution.

Peers Comparison

Key metrics vs top competitors for Exact Sciences Corporation (EXAS)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
EXAS logoEXASExact Sciences CorporationCurrent
$104.91$20.02B-95.3717.69%-6.4%-8.66%—
GH logoGHGuardant Health, Inc.
$162.92$21.6B-49.0732.88%-40.1%——
NTRA logoNTRANatera, Inc.
$281.27$40.28B-185.0535.9%-9.05%-15.13%—
ILMN logoILMNIllumina, Inc.
$191.76$29.13B35.19-0.78%19.43%32.84%—
LH logoLHLabcorp Holdings Inc.
$283.86$23.36B27.147.25%6.66%10.89%—
DGX logoDGXQuest Diagnostics Incorporated
$212.38$23.51B24.2711.78%9.08%13.8%—

Compare EXAS vs Peers

Exact Sciences Corporation (EXAS) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs GH

Most directly comparable listed peer for EXAS.

Scale Benchmark

vs TMO

Larger-name benchmark to compare EXAS against a more recognizable public peer.

Peer Set

Compare Top 5

vs GH, NTRA, ILMN, LH

EXAS SEC Filings & Documents

Exact Sciences Corporation (EXAS) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Mar 23, 2026·SEC

Material company update

Mar 20, 2026·SEC

Material company update

Feb 20, 2026·SEC

10-K Annual Reports

2
FY 2026

Feb 13, 2026·SEC

FY 2025

Feb 19, 2025·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 3, 2025·SEC

FY 2025

Aug 6, 2025·SEC

FY 2025

May 1, 2025·SEC

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EXAS Frequently Asked Questions

Exact Sciences Corporation (EXAS) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Exact Sciences Corporation's revenue?

Exact Sciences Corporation (EXAS) reported $3.25B in revenue for fiscal year 2025.

How fast is Exact Sciences Corporation growing?

Exact Sciences Corporation (EXAS) grew revenue by 17.7% over the past year. This is strong growth.

Is EXAS profitable?

Exact Sciences Corporation (EXAS) reported a net loss of $207.9M for fiscal year 2025.

Dividend & Returns
What is EXAS's return on equity?

Exact Sciences Corporation (EXAS) has a return on equity (ROE) of -8.7%. Negative ROE indicates the company is unprofitable.

What is Exact Sciences Corporation's free cash flow?

Exact Sciences Corporation (EXAS) generated $356.8M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

What if you invested $1,000 in EXAS back in 1999?

Total return calculator · dividends reinvested · 27+ years of data

See returns →