Denali Therapeutics Inc. (DNLI) Stock Price History
Historical prices from 2017 to 2026
- 1M
- +34.6%
- 3M
- +35.5%
- YTD
- +61.7%
- 1Y
- +84.6%
- 3Y
- -3.5%
- 5Y
- -19.2%
Loading 10-year price history...
DNLI Historical Performance
DNLI Annual Returns
Year-by-year price performance · 2017–2026
- 2017 annual price return
- -27.1%
- 2018 annual price return
- +28.1%
- 2019 annual price return
- -9.9%
- 2020 annual price return
- +411.0%
- 2021 annual price return
- -37.1%
- 2022 annual price return
- -41.2%
- 2023 annual price return
- -22.3%
- 2024 annual price return
- -4.7%
- 2025 annual price return
- -20.8%
- 2026 annual price return
- +30.2%
DNLI Stock Price Trajectory (2017–2026)
As of July 8, 2026, Denali Therapeutics Inc. (DNLI) trades at $26.31, representing a +84.6% return over the past year. The stock has delivered a -65.5% total return over five years (-19.2% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $93.94 on December 22, 2020. From this peak, DNLI has corrected -72.0%, currently trading 39% above its 200-day moving average, indicating continued institutional support.
When compared to Healthcare sector peers PRAX (+594.0% 1Y), ARVN (+10.3% 1Y), and RCUS (+268.0% 1Y), DNLI has underperformed the peer group average. Compare DNLI vs PRAX →
DNLI Historical Price Data · from 2017
Rows 1–50 of 2,154| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-07-07 | 26.02 | 26.76 | 25.36 | 26.31 | 1.41M | +2.21% |
| 2026-07-06 | 25.98 | 26.07 | 25.04 | 25.74 | 1.28M | -0.35% |
| 2026-07-02 | 26.17 | 26.80 | 25.43 | 25.83 | 1.50M | -0.58% |
| 2026-07-01 | 25.72 | 26.18 | 25.61 | 25.98 | 1.17M | +1.01% |
| 2026-06-30 | 26.00 | 26.36 | 25.63 | 25.72 | 1.92M | -0.66% |
| 2026-06-29 | 25.54 | 26.11 | 25.54 | 25.89 | 2.13M | +1.25% |
| 2026-06-26 | 24.78 | 25.70 | 24.67 | 25.57 | 0 | +3.40% |
| 2026-06-25 | 24.83 | 25.96 | 24.66 | 24.73 | 1.09M | -0.36% |
| 2026-06-24 | 25.09 | 25.69 | 24.71 | 24.82 | 1.12M | +0.20% |
| 2026-06-23 | 24.27 | 25.29 | 23.51 | 24.77 | 1.57M | +2.99% |
| 2026-06-22 | 23.80 | 24.34 | 23.64 | 24.05 | 1.53M | +3.17% |
| 2026-06-18 | 24.16 | 24.65 | 23.21 | 23.31 | 2.18M | -0.77% |
| 2026-06-17 | 22.28 | 24.20 | 22.09 | 23.49 | 2.54M | +7.11% |
| 2026-06-16 | 22.12 | 22.47 | 21.68 | 21.93 | 1.41M | -1.31% |
| 2026-06-15 | 21.86 | 22.44 | 21.41 | 22.22 | 1.25M | +2.59% |
| 2026-06-12 | 21.02 | 22.15 | 20.92 | 21.66 | 2.17M | +3.04% |
| 2026-06-11 | 20.78 | 21.68 | 20.37 | 21.02 | 1.92M | +1.99% |
| 2026-06-10 | 20.45 | 21.71 | 20.16 | 20.61 | 2.40M | -0.87% |
| 2026-06-09 | 19.84 | 20.92 | 19.45 | 20.79 | 1.86M | +6.40% |
| 2026-06-08 | 19.85 | 20.05 | 19.19 | 19.54 | 1.87M | +0.10% |
| 2026-06-05 | 19.89 | 19.94 | 19.24 | 19.52 | 2.15M | -3.08% |
| 2026-06-04 | 19.70 | 21.10 | 19.67 | 20.14 | 1.82M | +2.44% |
| 2026-06-03 | 19.34 | 19.69 | 19.19 | 19.66 | 1.01M | +1.60% |
| 2026-06-02 | 19.96 | 20.06 | 18.92 | 19.35 | 1.64M | -5.19% |
| 2026-06-01 | 20.86 | 20.86 | 20.03 | 20.41 | 1.50M | -2.99% |
| 2026-05-29 | 20.84 | 21.18 | 20.84 | 21.04 | 1.54M | +0.43% |
| 2026-05-28 | 20.10 | 21.05 | 19.66 | 20.95 | 1.31M | +3.66% |
| 2026-05-27 | 19.62 | 20.34 | 19.57 | 20.21 | 1.26M | +4.28% |
| 2026-05-26 | 18.86 | 19.63 | 18.60 | 19.38 | 2.10M | +3.97% |
| 2026-05-22 | 18.52 | 19.06 | 18.18 | 18.64 | 3.38M | -3.42% |
| 2026-05-21 | 18.55 | 19.33 | 18.35 | 19.30 | 1.18M | +2.50% |
| 2026-05-20 | 18.21 | 19.18 | 18.11 | 18.83 | 1.32M | +3.98% |
| 2026-05-19 | 17.96 | 18.40 | 17.71 | 18.11 | 2.10M | -1.58% |
| 2026-05-18 | 18.63 | 19.11 | 18.23 | 18.40 | 1.66M | -1.18% |
| 2026-05-15 | 19.01 | 19.37 | 18.50 | 18.62 | 2.13M | -3.97% |
| 2026-05-14 | 19.97 | 20.00 | 18.91 | 19.39 | 1.79M | -2.07% |
| 2026-05-13 | 19.45 | 19.95 | 19.29 | 19.80 | 1.13M | +1.75% |
| 2026-05-12 | 19.76 | 19.97 | 19.18 | 19.46 | 1.74M | -1.07% |
| 2026-05-11 | 19.69 | 20.55 | 19.43 | 19.67 | 1.71M | +0.25% |
| 2026-05-08 | 19.44 | 20.53 | 19.44 | 19.62 | 1.90M | -0.46% |
| 2026-05-07 | 20.25 | 20.41 | 19.19 | 19.71 | 1.21M | -3.38% |
| 2026-05-06 | 19.20 | 20.49 | 18.91 | 20.40 | 2.18M | +7.82% |
| 2026-05-05 | 19.15 | 19.40 | 18.33 | 18.92 | 810K | +1.34% |
| 2026-05-04 | 18.14 | 19.14 | 18.10 | 18.67 | 2.41M | +2.02% |
| 2026-05-01 | 18.70 | 18.81 | 18.23 | 18.30 | 1.42M | -2.24% |
| 2026-04-30 | 18.73 | 18.92 | 18.35 | 18.72 | 2.44M | +0.65% |
| 2026-04-29 | 19.60 | 20.17 | 18.23 | 18.60 | 2.95M | -7.28% |
| 2026-04-28 | 19.97 | 20.43 | 19.84 | 20.06 | 1000K | +0.60% |
| 2026-04-27 | 19.76 | 20.36 | 19.76 | 19.94 | 968K | +0.35% |
| 2026-04-24 | 20.05 | 20.05 | 19.27 | 19.87 | 1.00M | +2.16% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
DCA Calculator
See how regular investing compounds over time.
Peer Comparison
Compare growth, multiples, and margins vs sector.
DNLI — Frequently Asked Questions
Quick answers to the most common questions about buying DNLI stock.
How has DNLI stock performed recently?
DNLI returned +84.6% over the past year, beating its 5-year annualized CAGR of -19.2%. The stock trades above its 200-day moving average, confirming the uptrend.
What is DNLI's all-time high price?
Denali Therapeutics Inc. reached $93.94 on 2020-12-22. The 52-week high is $26.80. Current 1-year return of +84.6% places the stock closer to historical peaks.
Where can I download DNLI historical price data?
This page provides DNLI daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2017-2026, downloadable in CSV format.