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CGENCompugen Ltd.
$2.39$226M
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CGEN logoCompugen Ltd.(CGEN)Earnings, Financials & Key Ratios

CGEN•NASDAQ
$2.39
6.3× P/E·Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryDrug Discovery and Antibody Platforms
AboutCompugen Ltd., a clinical-stage therapeutic discovery and development company, researches, develops, and commercializes therapeutic and product candidates in Israel, the United States, and Europe. The company's immuno-oncology pipeline consists of COM701, an anti-PVRIG antibody that is in Phase I clinical study used for the treatment of solid tumors; COM902, a therapeutic antibody targeting TIGIT, which is in Phase I clinical study in patients with advanced malignancies as a monotherapy; Bapotulimab, a therapeutic antibody targeting ILDR2 that is in Phase I clinical study in patients with solid tumors; and AZD2936, a novel anti-TIGIT/PD-1 bispecific antibody, which is in Phase I/II clinical study in patients with advanced or metastatic non-small cell lung cancer. Its therapeutic pipeline also includes early-stage immuno-oncology programs focused primarily on myeloid targets. The company has collaboration agreement with Bayer Pharma AG for the research, development, and commercialization of antibody-based therapeutics against the company's immune checkpoint regulators; Bristol-Myers Squibb to evaluate the safety and tolerability of COM701 in combination with Bristol-Myers Squibb's PD-1 immune checkpoint inhibitor Opdivo in patients with advanced solid tumors; and Johns Hopkins School of Medicine to evaluate novel T cell and myeloid checkpoint targets. It has license agreement with AstraZeneca for the development of bi-specific and multi-specific immuno-oncology antibody products; and research collaboration with Johns Hopkins University for myeloid. Compugen Ltd. was incorporated in 1993 and is headquartered in Holon, Israel.Show more
  • Revenue$73M+161.1%
  • EBITDA$32M+320.8%
  • Net Income$35M+348.4%
  • EPS (Diluted)0.38+337.5%
  • Gross Margin87.29%+22.0%
  • EBITDA Margin43.7%+184.5%
  • Operating Margin43.05%+180.6%
  • Net Margin48.57%+195.1%
  • ROE44.84%+289.8%

CGEN Price & Volume

Compugen Ltd. (CGEN) stock price & volume — 10-year historical chart

Loading chart...

Milestone-Driven Revenue Masks Underlying Clinical Burn

Investment Thesis • Updated 2025Q4

VerdictNeutral
Growth:Mixed
Profitability:Strained
Financial:Healthy
Cash Flow:Mixed
Primary Risk:Binary clinical milestone dependence

Key Thesis Takeaways

  • Compugen's financial profile is defined by extreme volatility, where sporadic milestone payments create temporary profitability, such as the 84.4% net margin observed in 2025Q4.
  • While the company maintains a conservative capital structure with a 0.03 debt-to-equity ratio, its long-term viability remains tethered to the success of its discovery platform and the timing of future pharmaceutical partnerships.
  • Investors should remain cautious, as the business model historically relies on non-recurring inflows to offset persistent R&D expenditures that consistently range between $5.5M and $8.3M per quarter.

Verdict Logic

while the $90.6M cash position as of 2025Q4 provides a liquidity buffer, the company's dependence on binary clinical milestones makes its current 5.50 P/E ratio an unreliable indicator of long-term value.

CGEN Growth Metrics

Compugen Ltd. (CGEN) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years22.87%
5 Years105.2%
3 Years113.28%
TTM870.19%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM211.99%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM200.93%

Return on Capital

10 Years-34.58%
5 Years-13.55%
3 Years-1%
Last Year27.34%

CGEN Recent Earnings

Compugen Ltd. (CGEN) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)●Beat Revenue 4/12 qtrs (36%)
Q2 2026Latest
May 18, 2026
Metric
Actual
Est
EPS
$0.08-14.3%
$0.07
Rev
$2M+38.5%
$2M
Q2 2026
Mar 2, 2026
Metric
Actual
Est
EPS
$0.60+957.1%
$0.07
Rev
$67M+3018.2%
$2M
Q4 2025
Nov 10, 2025
Metric
Actual
Est
EPS
$0.07+22.2%
$0.09
Rev
$2M-86.8%
$14M
Q3 2025
Aug 6, 2025
Metric
Actual
Est
EPS
$0.08-14.3%
$0.07
Rev
$1M-14.5%
$1M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 18, 2026
$0.08vs $0.07-14.3%
$2Mvs $2M+38.5%
Q2 2026Mar 2, 2026
$0.60vs $0.07+957.1%
$67Mvs $2M+3018.2%
Q4 2025Nov 10, 2025
$0.07vs $0.09+22.2%
$2Mvs $14M-86.8%
Q3 2025Aug 6, 2025
$0.08vs $0.07-14.3%
$1Mvs $1M-14.5%
Based on last 12 quarters of dataView full earnings history →

Latest CGEN News

Recent stock market news and headlines for Compugen Ltd. (CGEN)

PRNewsWire·Jun 18, 2026
Compugen Presents a Trial-in-Progress Poster on the MAIA-ovarian Adaptive Platform Trial at ESMO Gynaecological Cancers Congress

HOLON, Israel, June 18, 2026 /PRNewswire/ -- Compugen Ltd. (Nasdaq: CGEN) (TASE: CGEN) a clinical-stage cancer immunotherapy company and a pioneer in computational drug target discovery powered by AI/ML, today presented a trial-in-progress poster on the MAIA-ovarian adaptive platform trial of COM701, a potential first-in-class anti-PVRIG antibody, at the ESMO Gynaecological Cancers Congress 2026, in Copenhagen, Denmark.

Seeking Alpha·Jun 15, 2026
Compugen Ltd. (CGEN) Discusses End-to-End AI-Driven Target Discovery in Immuno-Oncology Transcript

Compugen Ltd. (CGEN) Discusses End-to-End AI-Driven Target Discovery in Immuno-Oncology Transcript

Peers Comparison

Key metrics vs top competitors for Compugen Ltd. (CGEN)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
CGEN logoCGENCompugen Ltd.Current
$2.39$225.98M6.29161.14%48.57%44.84%—
RXRX logoRXRXRecursion Pharmaceuticals, Inc.
$3.84$1.72B-2.6726.92%-844.46%-54.32%—
SDGR logoSDGRSchrödinger, Inc.
$16.49$1.23B-11.7023.29%-40.6%-30.85%—
ABSI logoABSIAbsci Corporation
$11.33$1.77B-13.49-38.24%-6450.76%-63.58%—
INVA logoINVAInnoviva, Inc.
$22.25$1.64B6.7418.52%118.91%47.59%—
NKTX logoNKTXNkarta, Inc.
$3.38$241.82M-2.40——-30.9%—

Compare CGEN vs Peers

Compugen Ltd. (CGEN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs RXRX

Most directly comparable listed peer for CGEN.

Scale Benchmark

vs TMO

Larger-name benchmark to compare CGEN against a more recognizable public peer.

Peer Set

Compare Top 5

vs RXRX, SDGR, ABSI, INVA

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CGEN Frequently Asked Questions

Compugen Ltd. (CGEN) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Compugen Ltd.'s revenue?

Compugen Ltd. (CGEN) reported $72.8M in revenue for fiscal year 2025. This represents a 2148% increase from $3.2M in 1999.

How fast is Compugen Ltd. growing?

Compugen Ltd. (CGEN) grew revenue by 161.1% over the past year. This is strong growth.

Is CGEN profitable?

Yes, Compugen Ltd. (CGEN) is profitable, generating $35.3M in net income for fiscal year 2025 (48.6% net margin).

Dividend & Returns
What is CGEN's return on equity?

Compugen Ltd. (CGEN) has a return on equity (ROE) of 44.8%. This is excellent, indicating efficient use of shareholder capital.

What is Compugen Ltd.'s free cash flow?

Compugen Ltd. (CGEN) generated $31.3M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

What if you invested $1,000 in CGEN back in 1999?

Total return calculator · dividends reinvested · 27+ years of data

See returns →