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RZLTRezolute, Inc.
$4.91$473M
Overview & Verdict
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RZLT logoRezolute, Inc.(RZLT)Earnings, Financials & Key Ratios

RZLT•NASDAQ
$4.95
Price updated Jul 2, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryMetabolic and Obesity Therapies
AboutRezolute, Inc., a clinical stage biopharmaceutical company, develops transformative therapies for metabolic diseases associated with chronic glucose imbalance in the United States. The company's lead product candidate is RZ358, a human monoclonal antibody that is in Phase 2b clinical trial for the treatment of congenital hyperinsulinism, an ultra-rare pediatric genetic disorder. It is also developing RZ402, a selective and potent plasma kallikrein inhibitor, which is in Phase 1 clinical trial for the chronic treatment of diabetic macular edema. The company was formerly known as AntriaBio, Inc. and changed its name to Rezolute, Inc. in December 2017. Rezolute, Inc. was founded in 2010 and is headquartered in Redwood City, California.Show more
  • Revenue$0
  • EBITDA-$80M-13.5%
  • Net Income-$74M-8.7%
  • EPS (Diluted)-0.98+26.3%
  • ROE-52.56%+8.9%

RZLT Price & Volume

Rezolute, Inc. (RZLT) stock price & volume — 10-year historical chart

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Clinical Development Costs Threaten Future Liquidity

Investment Thesis • Updated 2026Q3

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical trial funding dependency

Key Thesis Takeaways

  • Rezolute remains in a high-risk, pre-revenue phase as it advances the SunRISE Phase 3 clinical trial for RZ358, which continues to drive substantial quarterly operating losses.
  • While the company maintains a low debt-to-equity ratio of 0.01, the rapid depletion of cash reserves from $94.1 million in 2025Q4 to $11.2 million in 2026Q3 suggests an urgent need for additional capital.
  • Investors should monitor the potential for further equity dilution, as the current financial trajectory indicates that existing resources may be insufficient to reach commercialization.

Verdict Logic

the rapid decline in cash reserves from $94.1 million to $11.2 million over three quarters suggests a high probability of near-term dilutive financing to sustain clinical operations.

RZLT Growth Metrics

Rezolute, Inc. (RZLT) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-11.63%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM29.31%

Return on Capital

10 Years-4273.62%
5 Years-58.85%
3 Years-51.91%
Last Year-55.73%

RZLT Recent Earnings

Rezolute, Inc. (RZLT) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)
Q2 2026Latest
May 12, 2026
Metric
Actual
Est
EPS
$0.16-12.3%
$0.14
Rev
—
—
Q1 2026
Feb 12, 2026
Metric
Actual
Est
EPS
$0.22-37.5%
$0.16
Rev
—
—
Q4 2025
Nov 6, 2025
Metric
Actual
Est
EPS
$0.18+33.3%
$0.27
Rev
—
—
Q4 2025
Sep 17, 2025
Metric
Actual
Est
EPS
$0.26-13.0%
$0.23
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 12, 2026
$0.16vs $0.14-12.3%
—
Q1 2026Feb 12, 2026
$0.22vs $0.16-37.5%
—
Q4 2025Nov 6, 2025
$0.18vs $0.27+33.3%
—
Q4 2025Sep 17, 2025
$0.26vs $0.23-13.0%
—
Based on last 12 quarters of dataView full earnings history →

Latest RZLT News

Recent stock market news and headlines for Rezolute, Inc. (RZLT)

GlobeNewsWire·Jun 17, 2026
Rezolute Highlights Results Presented from Natural History Outcomes Studies and its Ersodetug Clinical Program in Hyperinsulinism at Annual Meeting of the Endocrine Society

Presentations included analyses of natural history and adverse outcomes in congenital hyperinsulinism (HI), as well as previously reported results from the Company's Phase 3 sunRIZE study in congenital HI and a case series from its Expanded Access Program (EAP) in tumor HI REDWOOD CITY, Calif., June 17, 2026 (GLOBE NEWSWIRE) -- Rezolute, Inc. (Nasdaq: RZLT) (“Rezolute” or the “Company”), a late-stage ultra-rare disease company focused on treating refractory hypoglycemia caused by a congenital or any acquired form of hyperinsulinism (HI), today highlighted four data presentations delivered at the Annual Meeting of the Endocrine Society (ENDO).

Peers Comparison

Key metrics vs top competitors for Rezolute, Inc. (RZLT)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
RZLT logoRZLTRezolute, Inc.Current
$4.95$476.65M-5.05——-52.56%—
XOMA logoXOMAXOMA Royalty Corp.
$42.62$534.5M29.1983.06%86.97%30.21%—
CGEM logoCGEMCullinan Therapeutics, Inc.
$17.28$1.06B-4.65——-51.45%—
RARE logoRAREUltragenyx Pharmaceutical Inc.
$32.38$3.18B-5.5520.13%-91.03%——
VNDA logoVNDAVanda Pharmaceuticals Inc.
$6.05$357.6M-1.628.72%-109.99%-61.41%—
FOLD logoFOLDAmicus Therapeutics, Inc.
$14.49$4.55B-164.8520.05%-4.27%-12.02%—

Compare RZLT vs Peers

Rezolute, Inc. (RZLT) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs XOMA

Most directly comparable listed peer for RZLT.

Scale Benchmark

vs LLY

Larger-name benchmark to compare RZLT against a more recognizable public peer.

Peer Set

Compare Top 5

vs XOMA, CGEM, RARE, VNDA

RZLT SEC Filings & Documents

Rezolute, Inc. (RZLT) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 12, 2026·SEC

Material company update

May 4, 2026·SEC

Material company update

Mar 24, 2026·SEC

10-K Annual Reports

2
FY 2025

Sep 17, 2025·SEC

FY 2024

Sep 19, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 12, 2026·SEC

FY 2026

Feb 12, 2026·SEC

FY 2025

Nov 6, 2025·SEC

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RZLT Frequently Asked Questions

Rezolute, Inc. (RZLT) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is RZLT profitable?

Rezolute, Inc. (RZLT) reported a net loss of $81.5M for fiscal year 2025.

Dividend & Returns
What is RZLT's return on equity?

Rezolute, Inc. (RZLT) has a return on equity (ROE) of -52.6%. Negative ROE indicates the company is unprofitable.

What is Rezolute, Inc.'s free cash flow?

Rezolute, Inc. (RZLT) had negative free cash flow of $73.5M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in RZLT back in 2012?

Total return calculator · dividends reinvested · 14+ years of data

See returns →