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PTCTPTC Therapeutics, Inc.
$85.44$7.1B
Overview & Verdict
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PTCT logoPTC Therapeutics, Inc.(PTCT)Earnings, Financials & Key Ratios

PTCT•NASDAQ
$85.44
11.0× P/E·Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Rare Disease Biopharma
AboutPTC Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of medicines to patients with rare disorders. Its portfolio pipeline includes commercial products and product candidates in various stages of development, including clinical, pre-clinical and research and discovery stages, focuses on the development of treatments for multiple therapeutic areas, such as rare diseases. The company offers Translarna and Emflaza for the treatment of Duchenne muscular dystrophy in the European Economic Area and the United States, as well as to treat nonsense mutation Duchenne muscular dystrophy in Brazil and Russia; commercializes Tegsedi and Waylivra for the treatment of rare diseases in Latin America and the Caribbean; and markets Evrysdi for the treatment of spinal muscular atrophy in adults and children two months and older in Brazil. The company's splicing platform includes PTC518, which is being developed for the treatment of Huntington's disease. PTC Therapeutics, Inc. has collaborations with F. Hoffman-La Roche Ltd and Hoffman-La Roche Inc., as well as the Spinal Muscular Atrophy Foundation to advance drug discovery and development research in regenerative medicine; and Akcea Therapeutics, Inc. to commercialize Tegsedi and Waylivra for the treatment of rare diseases in Latin America and the Caribbean. PTC Therapeutics, Inc. was incorporated in 1998 and is headquartered in South Plainfield, New Jersey.Show more
  • Revenue$1.73B+114.5%
  • EBITDA$895M+494.6%
  • Net Income$683M+287.9%
  • EPS (Diluted)7.78+264.5%
  • Gross Margin95.85%+3.2%
  • EBITDA Margin51.73%+283.9%
  • Operating Margin49.49%+232.0%
  • Net Margin39.44%+187.6%

PTCT Price & Volume

PTC Therapeutics, Inc. (PTCT) stock price & volume — 10-year historical chart

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Divestiture Dependency Masks Persistent Operational Cash Burn

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Regulatory binary outcome risk

Key Thesis Takeaways

  • PTC Therapeutics faces a challenging fundamental outlook characterized by a reliance on non-recurring royalty monetization events to offset structural deficits in its core rare disease franchise.
  • While the company maintains a cash position of $834.0 million, the absence of sustainable profitability and the potential regulatory withdrawal of the Translarna asset in Europe create significant long-term uncertainty.
  • Investors should monitor the company's ability to transition from high-cost R&D development to a self-sustaining commercial model, as current operations continue to struggle with a $3.0 billion accumulated deficit in retained earnings.

Verdict Logic

the company's core operations are currently unable to sustain its $100.9 million quarterly R&D intensity without relying on non-recurring asset sales, which have already caused cash reserves to decline from $1.5 billion in 2025Q1 to $834.0 million in 2026Q1.

PTCT Growth Metrics

PTC Therapeutics, Inc. (PTCT) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years46.99%
5 Years35.37%
3 Years35.3%
TTM-53.34%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-131.39%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-135.85%

Return on Capital

10 Years-19.61%
5 Years-11.64%
3 Years-1.03%
Last Year55.86%

PTCT Recent Earnings

PTC Therapeutics, Inc. (PTCT) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 7/12 qtrs (58%)●Beat Revenue 6/12 qtrs (50%)
Q2 2026Latest
May 7, 2026
Metric
Actual
Est
EPS
$0.03+93.3%
$0.45
Rev
$273M+25.4%
$217M
Q1 2026
Feb 19, 2026
Metric
Actual
Est
EPS
$1.67-695.2%
$0.21
Rev
$165M-41.1%
$279M
Q4 2025
Nov 4, 2025
Metric
Actual
Est
EPS
$0.20+116.8%
$1.19
Rev
$211M-25.0%
$281M
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.83+22.4%
$1.07
Rev
$179M-6.6%
$191M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$0.03vs $0.45+93.3%
$273Mvs $217M+25.4%
Q1 2026Feb 19, 2026
$1.67vs $0.21-695.2%
$165Mvs $279M-41.1%
Q4 2025Nov 4, 2025
$0.20vs $1.19+116.8%
$211Mvs $281M-25.0%
Q3 2025Aug 7, 2025
$0.83vs $1.07+22.4%
$179Mvs $191M-6.6%
Based on last 12 quarters of dataView full earnings history →

Latest PTCT News

Recent stock market news and headlines for PTC Therapeutics, Inc. (PTCT)

Zacks Investment Research·4 days ago
CPRX's Agamree Shows Potential Beyond DMD After Positive Phase I Data

Catalyst Pharmaceuticals' Agamree matches Emflaza's glucocorticoid activity while showing less immunosuppression, supporting potential expansion into new rare disease indications.

Zacks Investment Research·Jun 18, 2026
PTC Therapeutics (PTCT) Moves 7.2% Higher: Will This Strength Last?

PTC Therapeutics (PTCT) saw its shares surge in the last session with trading volume being higher than average. The latest trend in earnings estimate revisions could translate into further price increase in the near term.

PRNewsWire·Jun 17, 2026
PTC Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

WARREN, N.J., June 17, 2026 /PRNewswire/ -- PTC Therapeutics, Inc. (NASDAQ: PTCT) today announced that on June 11, 2026, the company approved non-statutory stock options to purchase an aggregate of 10,050 shares of its common stock and 11,870 restricted stock units ("RSUs"), each representing the right to receive one share of its common stock upon vesting, to 18 new employees.

GuruFocus·Jun 16, 2026
PTC Therapeutics Announces Pricing of Convertible Notes Offering to Refinance 2026 Convertible Notes

PTC Therapeutics Announces Pricing of Convertible Notes Offering to Refinance 2026 Convertible Notes PR Newswire

PRNewsWire·Jun 16, 2026
PTC Therapeutics Announces Pricing of Convertible Notes Offering to Refinance 2026 Convertible Notes

– Refinancing transaction with proceeds to be utilized to repurchase or repay the 2026 convertible notes prior to or at maturity – – Offering made at 0% interest with conversion price of $107.48, a 40% premium over the closing price on June 15, 2026 – WARREN, N.J., June 15, 2026 /PRNewswire/ -- PTC Therapeutics, Inc., (NASDAQ: PTCT) today announced the pricing of $500.0 million aggregate principal amount of 0% Convertible Senior Notes due 2031 (the "Notes") in a private placement (the "Offering") to qualified institutional buyers pursuant to Rule 144A under the Securities Act of 1933, as amended (the "Securities Act").

Peers Comparison

Key metrics vs top competitors for PTC Therapeutics, Inc. (PTCT)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
PTCT logoPTCTPTC Therapeutics, Inc.Current
$85.44$7.09B10.98114.51%39.44%——
SRPT logoSRPTSarepta Therapeutics, Inc.
$19.18$2.02B-2.6915.58%2.98%4.89%—
BMRN logoBMRNBioMarin Pharmaceutical Inc.
$58.79$11.31B32.6612.87%8.29%4.41%—
RARE logoRAREUltragenyx Pharmaceutical Inc.
$33.70$3.31B-5.7820.13%-91.03%——
ALNY logoALNYAlnylam Pharmaceuticals, Inc.
$313.04$41.77B134.3565.19%13.46%98.29%—
ACAD logoACADACADIA Pharmaceuticals Inc.
$25.77$4.41B11.2511.87%34.3%35.65%—

Compare PTCT vs Peers

PTC Therapeutics, Inc. (PTCT) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs SRPT

Most directly comparable listed peer for PTCT.

Scale Benchmark

vs VRTX

Larger-name benchmark to compare PTCT against a more recognizable public peer.

Peer Set

Compare Top 5

vs SRPT, BMRN, RARE, ALNY

PTCT SEC Filings & Documents

PTC Therapeutics, Inc. (PTCT) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 7, 2026·SEC

Material company update

Apr 28, 2026·SEC

Material company update

Mar 25, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 19, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 29, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 4, 2025·SEC

FY 2025

Aug 7, 2025·SEC

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PTCT Frequently Asked Questions

PTC Therapeutics, Inc. (PTCT) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is PTC Therapeutics, Inc.'s revenue?

PTC Therapeutics, Inc. (PTCT) reported $827.1M in revenue for fiscal year 2025. This represents a 736% increase from $99.0M in 2011.

How fast is PTC Therapeutics, Inc. growing?

PTC Therapeutics, Inc. (PTCT) grew revenue by 114.5% over the past year. This is strong growth.

Is PTCT profitable?

PTC Therapeutics, Inc. (PTCT) reported a net loss of $186.7M for fiscal year 2025.

Dividend & Returns
What is PTC Therapeutics, Inc.'s free cash flow?

PTC Therapeutics, Inc. (PTCT) had negative free cash flow of $229.0M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in PTCT back in 2011?

Total return calculator · dividends reinvested · 15+ years of data

See returns →