Investors interested in Medical - Biomedical and Genetics stocks are likely familiar with Sarepta Therapeutics (SRPT) and Prothena (PRTA). But which of these two stocks is more attractive to value investors?

Prothena Corporation plc (PRTA) stock price & volume — 10-year historical chart
Investment Thesis • Updated 2026Q1
the company's reliance on unpredictable milestone payments to offset its $1.3 billion accumulated deficit creates significant liquidity risk for long-term investors.
Prothena Corporation plc (PRTA) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR
Prothena Corporation plc (PRTA) EPS & revenue vs analyst estimates — last 4 quarters
| Quarter | Date | EPS (Act vs Est) | Revenue (Act vs Est) |
|---|---|---|---|
| Q2 2026Latest | May 7, 2026 | $0.52vs $0.31+267.7% | $51Mvs $808,909+6215.2% |
| Q1 2026 | Feb 19, 2026 | $0.44vs $0.45+2.2% | $21,000vs $1M-98.4% |
| Q4 2025 | Nov 6, 2025 | $0.67vs $0.60-11.7% | $2Mvs $666,670+262.2% |
| Q3 2025 | Aug 4, 2025 | $1.86vs $1.11-67.6% | $4Mvs $7M-33.4% |
Recent stock market news and headlines for Prothena Corporation plc (PRTA)
Investors interested in Medical - Biomedical and Genetics stocks are likely familiar with Sarepta Therapeutics (SRPT) and Prothena (PRTA). But which of these two stocks is more attractive to value investors?

Key metrics vs top competitors for Prothena Corporation plc (PRTA)
| Company | Price | Market Cap | P/E Ratio | Rev Growth (1Y) | Net Margin | ROE | Div Yield |
|---|---|---|---|---|---|---|---|
| $9.68 | $506.78M | -2.14 | -92.84% | -2520.57% | -63.62% | — | |
| $14.49 | $4.55B | -164.85 | 20.05% | -4.27% | -12.02% | — | |
| $35.87 | $3.53B | -6.15 | 20.13% | -91.03% | — | — | |
| $86.33 | $14.27B | -36.27 | 33.87% | -30.87% | -58.57% | — | |
| $321.59 | $42.91B | 138.02 | 65.19% | 13.46% | 98.29% | — | |
| $30.25 | $3.05B | -9.19 | -4.26% | -156.36% | -68.97% | — |
Prothena Corporation plc (PRTA) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
Prothena Corporation plc (PRTA) SEC filings — annual & quarterly reports (10-K, 10-Q)
May 15, 2026·SEC
May 7, 2026·SEC
Feb 27, 2026·SEC
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Prothena Corporation plc (PRTA) stock FAQ — growth, dividends, profitability & financials explained
Prothena Corporation plc (PRTA) reported $57.9M in revenue for fiscal year 2025. This represents a 4561% increase from $1.2M in 2010.
Prothena Corporation plc (PRTA) saw revenue decline by 92.8% over the past year.
Prothena Corporation plc (PRTA) reported a net loss of $151.2M for fiscal year 2025.
Prothena Corporation plc (PRTA) has a return on equity (ROE) of -63.6%. Negative ROE indicates the company is unprofitable.
Prothena Corporation plc (PRTA) had negative free cash flow of $81.4M in fiscal year 2025, likely due to heavy capital investments.