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PMNProMIS Neurosciences, Inc.
$13.71$89M
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PMN logoProMIS Neurosciences, Inc.(PMN)Earnings, Financials & Key Ratios

PMN•NASDAQ
$13.71
Price updated Jul 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutProMIS Neurosciences, Inc. discovers and develops precision medicine solutions for the treatment of neurodegenerative diseases, primarily Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), and multiple system atrophy (MSA) in Canada. The company's proprietary discovery platform comprises ProMIS and Collective Coordinates algorithms to predict novel targets known as disease specific epitopes on the molecular surface of misfolded proteins. Its lead product candidates include PMN310, a monoclonal antibody (mAb) for toxic oligomers in AD; PMN267, a superoxide dismustase 1 and TAR-DNA binding protein 43 in ALS, as well as alpha synuclein in Parkinson's disease and Lewy body dementia; and PMN442, a mAb targeting toxic a-syn oligomers and seeding fibrils in MSA. The company was formerly known as Amorfix Life Sciences Ltd. and changed its name to ProMIS Neurosciences, Inc. in July 2015. ProMIS Neurosciences, Inc. was incorporated in 2004 and is headquartered in Toronto, Canada.Show more
  • Revenue$0
  • EBITDA-$40M-1490.9%
  • Net Income-$40M-1529.3%
  • EPS (Diluted)-22.61-922.2%
  • ROE-521.61%-1999.7%

PMN Price & Volume

ProMIS Neurosciences, Inc. (PMN) stock price & volume — 10-year historical chart

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Clinical Development Costs Outpace Capital Reserves

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Imminent liquidity and dilution

Key Thesis Takeaways

  • ProMIS Neurosciences remains a high-risk, pre-revenue biotechnology entity heavily reliant on external financing to sustain its PMN310 clinical program.
  • While the company focuses exclusively on R&D, the lack of commercial revenue and persistent operating losses create a precarious financial outlook.
  • Investors should monitor the company's ability to secure non-dilutive funding, as the current trajectory suggests significant ongoing capital requirements that may continue to erode shareholder equity.

Verdict Logic

the company's cash position of $6.1 million against quarterly operating losses exceeding $8 million suggests an imminent liquidity crisis that likely necessitates highly dilutive equity financing.

PMN Growth Metrics

ProMIS Neurosciences, Inc. (PMN) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-4248.84%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-2270.85%

Return on Capital

10 Years-579.25%
5 Years-347.23%
3 Years-480.58%
Last Year-519.51%

PMN Recent Earnings

ProMIS Neurosciences, Inc. (PMN) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)
Q2 2026Latest
May 12, 2026
Metric
Actual
Est
EPS
$1.26-18.9%
$1.06
Rev
—
—
Q2 2026
May 11, 2026
Metric
Actual
Est
EPS
$1.26-18.9%
$1.06
Rev
—
—
Q2 2026
Mar 25, 2026
Metric
Actual
Est
EPS
$4.11+11.8%
$4.66
Rev
—
—
Q4 2025
Nov 12, 2025
Metric
Actual
Est
EPS
$6.00-60.0%
$3.75
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 12, 2026
$1.26vs $1.06-18.9%
—
Q2 2026May 11, 2026
$1.26vs $1.06-18.9%
—
Q2 2026Mar 25, 2026
$4.11vs $4.66+11.8%
—
Q4 2025Nov 12, 2025
$6.00vs $3.75-60.0%
—
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for ProMIS Neurosciences, Inc. (PMN)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
PMN logoPMNProMIS Neurosciences, Inc.Current
$13.71$89.5M-0.61——-521.61%—
PRTA logoPRTAProthena Corporation plc
$9.50$497.36M-2.10-92.84%-260.92%-49.88%—
ARVN logoARVNArvinas, Inc.
$8.45$545.2M-6.60-0.3%-247.54%-44.39%—
ACAD logoACADACADIA Pharmaceuticals Inc.
$25.77$4.41B11.2511.87%34.3%35.65%—
SAVA logoSAVACassava Sciences, Inc.
$1.32$63.77M-2.54——-95.77%—
NRXP logoNRXPNRx Pharmaceuticals, Inc.
$3.95$68.19M-2.94—-1070.26%——

Compare PMN vs Peers

ProMIS Neurosciences, Inc. (PMN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PRTA

Most directly comparable listed peer for PMN.

Scale Benchmark

vs LLY

Larger-name benchmark to compare PMN against a more recognizable public peer.

Peer Set

Compare Top 5

vs PRTA, ARVN, ACAD, SAVA

PMN SEC Filings & Documents

ProMIS Neurosciences, Inc. (PMN) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 20, 2026·SEC

Material company update

May 12, 2026·SEC

Material company update

Mar 25, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 25, 2026·SEC

FY 2025

Mar 31, 2025·SEC

FY 2024

Apr 1, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 12, 2026·SEC

FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 13, 2025·SEC

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PMN Frequently Asked Questions

ProMIS Neurosciences, Inc. (PMN) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is PMN profitable?

ProMIS Neurosciences, Inc. (PMN) reported a net loss of $40.6M for fiscal year 2025.

Dividend & Returns
What is PMN's return on equity?

ProMIS Neurosciences, Inc. (PMN) has a return on equity (ROE) of -521.6%. Negative ROE indicates the company is unprofitable.

What is ProMIS Neurosciences, Inc.'s free cash flow?

ProMIS Neurosciences, Inc. (PMN) had negative free cash flow of $35.5M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in PMN back in 2006?

Total return calculator · dividends reinvested · 20+ years of data

See returns →