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NAUTNautilus Biotechnology, Inc.
$1.69$215M
Overview & Verdict
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NAUT logoNautilus Biotechnology, Inc.(NAUT)Earnings, Financials & Key Ratios

NAUT•NASDAQ
$1.69
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryDiagnostics and Omics Tools
AboutNautilus Biotechnology, Inc., a development stage life sciences company, engages in creating a platform technology for quantifying and unlocking the complexity of the proteome. It develops Nautilus Platform, a proteomics platform that includes end-to-end solution comprised of instruments, consumables, and software analysis. The company was founded in 2016 and is headquartered in Seattle, Washington.Show more
  • Revenue$0
  • EBITDA-$60M+19.6%
  • Net Income-$59M+16.6%
  • EPS (Diluted)-0.47+16.1%
  • ROE-32.27%-8.1%

NAUT Price & Volume

Nautilus Biotechnology, Inc. (NAUT) stock price & volume — 10-year historical chart

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Pre-Revenue Proteomics Platform Faces Liquidity Constraints

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Imminent liquidity and commercialization

Key Thesis Takeaways

  • Nautilus Biotechnology remains a high-risk, pre-commercial entity with no revenue generation over the last ten quarters, necessitating a critical evaluation of its ability to reach market viability.
  • The company's heavy reliance on R&D, which averaged $10.8 million per quarter, continues to erode its asset base, which has contracted from $305.6 million in 2023Q4 to $177.8 million in 2026Q1.
  • Investors should monitor the company's ability to secure additional capital, as the current cash position of $12.4 million appears insufficient to sustain its ongoing operational burn rate.

Verdict Logic

the company's cash position of $12.4 million is critically low relative to its historical quarterly free cash flow burn of approximately $14 million, indicating a high probability of near-term dilution or insolvency risk.

NAUT Growth Metrics

Nautilus Biotechnology, Inc. (NAUT) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM16.86%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM14.81%

Return on Capital

10 Years-30.67%
5 Years-25%
3 Years-28.81%
Last Year-31.96%

NAUT Recent Earnings

Nautilus Biotechnology, Inc. (NAUT) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 12/12 qtrs (100%)
Q2 2026Latest
Apr 28, 2026
Metric
Actual
Est
EPS
$0.12+17.2%
$0.14
Rev
—
$250,000
Q1 2026
Feb 26, 2026
Metric
Actual
Est
EPS
$0.11+21.4%
$0.14
Rev
—
$1M
Q4 2025
Oct 27, 2025
Metric
Actual
Est
EPS
$0.11+26.7%
$0.15
Rev
—
—
Q3 2025
Jul 31, 2025
Metric
Actual
Est
EPS
$0.12+22.6%
$0.15
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestApr 28, 2026
$0.12vs $0.14+17.2%
—vs $250,000
Q1 2026Feb 26, 2026
$0.11vs $0.14+21.4%
—vs $1M
Q4 2025Oct 27, 2025
$0.11vs $0.15+26.7%
—
Q3 2025Jul 31, 2025
$0.12vs $0.15+22.6%
—
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Nautilus Biotechnology, Inc. (NAUT)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
NAUT logoNAUTNautilus Biotechnology, Inc.Current
$1.69$214.76M-3.60——-32.27%—
CDNA logoCDNACareDx, Inc
$28.31$1.46B-70.7813.79%-1.98%-2.61%—
SEER logoSEERSeer, Inc.
$2.22$122.06M-1.7315.57%-468.74%-26.58%—
QBTS logoQBTSD-Wave Quantum Inc.
$21.06$7.73B-18.97178.54%-2957.23%-44.05%—
ILMN logoILMNIllumina, Inc.
$191.76$29.13B35.19-0.78%19.43%32.84%—
PACB logoPACBPacific Biosciences of California, Inc.
$1.56$484.54M-0.863.89%-80.34%-488.45%—

Compare NAUT vs Peers

Nautilus Biotechnology, Inc. (NAUT) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs CDNA

Most directly comparable listed peer for NAUT.

Scale Benchmark

vs TMO

Larger-name benchmark to compare NAUT against a more recognizable public peer.

Peer Set

Compare Top 5

vs CDNA, SEER, QBTS, ILMN

NAUT SEC Filings & Documents

Nautilus Biotechnology, Inc. (NAUT) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 28, 2026·SEC

Material company update

Nov 4, 2025·SEC

Material company update

Oct 28, 2025·SEC

10-K Annual Reports

5
FY 2026

Feb 26, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Apr 28, 2026·SEC

FY 2025

Oct 28, 2025·SEC

FY 2025

Jul 31, 2025·SEC

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NAUT Frequently Asked Questions

Nautilus Biotechnology, Inc. (NAUT) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is NAUT profitable?

Nautilus Biotechnology, Inc. (NAUT) reported a net loss of $57.1M for fiscal year 2025.

Dividend & Returns
What is NAUT's return on equity?

Nautilus Biotechnology, Inc. (NAUT) has a return on equity (ROE) of -32.3%. Negative ROE indicates the company is unprofitable.

What is Nautilus Biotechnology, Inc.'s free cash flow?

Nautilus Biotechnology, Inc. (NAUT) had negative free cash flow of $51.4M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in NAUT back in 2018?

Total return calculator · dividends reinvested · 8+ years of data

See returns →