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ALECAlector, Inc.
$2.06$229M
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ALEC logoAlector, Inc.(ALEC)Earnings, Financials & Key Ratios

ALEC•NASDAQ
$2.01
Price updated Jul 2, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutAlector, Inc., a clinical stage biopharmaceutical company, develops therapies for the treatment of neurodegeneration diseases. Its products include AL001, a humanized recombinant monoclonal antibody, which is in Phase III clinical trial for the treatment of frontotemporal dementia, Alzheimer's, Parkinson's, and amyotrophic lateral sclerosis diseases; and AL101 that is in Phase I clinical trial for the treatment of neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. The company also offers AL002, a product candidate that is in Phase II clinical trial for the treatment of Alzheimer's disease; and AL003, which is in Phase I clinical trial for the treatment of Alzheimer's disease. In addition, its products in development stage include AL044 that targets MS4A4A, a risk gene for Alzheimer's disease. Alector, Inc. has a collaboration agreement with Adimab, LLC for the research and development of antibodies; and a strategic collaboration agreement with GlaxoSmithKline plc for the development and commercialization of monoclonal antibodies, such as AL001 and AL101 to treat neurodegenerative diseases. The company was founded in 2013 and is headquartered in South San Francisco, California.Show more
  • Revenue$21M-79.1%
  • EBITDA-$136M
  • Net Income-$143M-20.1%
  • EPS (Diluted)-1.39-13.0%
  • Gross Margin54.09%-45.9%
  • EBITDA Margin-646.93%-377.8%
  • Operating Margin-692.83%-380.5%
  • Net Margin-679.16%-473.7%
  • ROE-181.56%-99.0%

ALEC Price & Volume

Alector, Inc. (ALEC) stock price & volume — 10-year historical chart

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Clinical Pipeline Costs Threaten Alector Liquidity Position

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Imminent liquidity depletion risk

Key Thesis Takeaways

  • Alector faces a precarious financial outlook as its immuno-neurology pipeline development continues to outpace revenue generation, leading to a rapid erosion of shareholder equity from $134.2 million in 2023Q4 to $10.4 million in 2026Q1.
  • The company's reliance on lumpy milestone-based revenue, which saw a 71.5% year-over-year contraction in 2026Q1, creates significant uncertainty regarding its ability to fund late-stage clinical trials.
  • Investors should monitor the firm's critical cash position of $77.0 million as of 2026Q1, as the current burn rate suggests a high probability of future dilutive financing to sustain operations.

Verdict Logic

the company's rapid depletion of cash reserves to $77.0 million against significant quarterly operating losses suggests an imminent risk of shareholder dilution that outweighs current pipeline potential.

ALEC Growth Metrics

Alector, Inc. (ALEC) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-0.05%
3 Years-46%
TTM-79.15%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-1.58%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM6.38%

Return on Capital

10 Years-30.34%
5 Years-28.38%
3 Years-38.32%
Last Year-51.43%

ALEC Recent Earnings

Alector, Inc. (ALEC) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 12/12 qtrs (100%)●Beat Revenue 8/12 qtrs (67%)
Q2 2026Latest
May 7, 2026
Metric
Actual
Est
EPS
$0.21+40.0%
$0.35
Rev
$1M-89.2%
$10M
Q1 2026
Feb 25, 2026
Metric
Actual
Est
EPS
$0.34+12.8%
$0.39
Rev
$6M+218.6%
$2M
Q4 2025
Nov 6, 2025
Metric
Actual
Est
EPS
$0.34+19.0%
$0.42
Rev
$3M+82.8%
$2M
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.30+33.3%
$0.45
Rev
$8M+180.7%
$3M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$0.21vs $0.35+40.0%
$1Mvs $10M-89.2%
Q1 2026Feb 25, 2026
$0.34vs $0.39+12.8%
$6Mvs $2M+218.6%
Q4 2025Nov 6, 2025
$0.34vs $0.42+19.0%
$3Mvs $2M+82.8%
Q3 2025Aug 7, 2025
$0.30vs $0.45+33.3%
$8Mvs $3M+180.7%
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Alector, Inc. (ALEC)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
ALEC logoALECAlector, Inc.Current
$2.01$223.16M-1.45-79.07%-679.16%-181.56%—
PRTA logoPRTAProthena Corporation plc
$9.58$501.54M-2.11-92.84%-260.92%-49.88%—
ACAD logoACADACADIA Pharmaceuticals Inc.
$25.20$4.31B11.0011.87%34.3%35.65%—
SAVA logoSAVACassava Sciences, Inc.
$1.32$63.77M-2.54——-95.77%—
AVXL logoAVXLAnavex Life Sciences Corp.
$2.58$239.09M-4.78——-38.76%—
INMB logoINMBINmune Bio, Inc.
$1.68$44.66M-0.90257.14%—-170.86%—

Compare ALEC vs Peers

Alector, Inc. (ALEC) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PRTA

Most directly comparable listed peer for ALEC.

Scale Benchmark

vs LLY

Larger-name benchmark to compare ALEC against a more recognizable public peer.

Peer Set

Compare Top 5

vs PRTA, ACAD, SAVA, AVXL

ALEC SEC Filings & Documents

Alector, Inc. (ALEC) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 7, 2026·SEC

Material company update

May 7, 2026·SEC

Material company update

Feb 25, 2026·SEC

10-K Annual Reports

4
FY 2026

Feb 25, 2026·SEC

FY 2025

Feb 26, 2025·SEC

FY 2024

Feb 27, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 7, 2025·SEC

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ALEC Frequently Asked Questions

Alector, Inc. (ALEC) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Alector, Inc.'s revenue?

Alector, Inc. (ALEC) reported $18.4M in revenue for fiscal year 2025. This represents a 4327% increase from $0.4M in 2016.

How fast is Alector, Inc. growing?

Alector, Inc. (ALEC) saw revenue decline by 79.1% over the past year.

Is ALEC profitable?

Alector, Inc. (ALEC) reported a net loss of $125.4M for fiscal year 2025.

Dividend & Returns
What is ALEC's return on equity?

Alector, Inc. (ALEC) has a return on equity (ROE) of -181.6%. Negative ROE indicates the company is unprofitable.

What is Alector, Inc.'s free cash flow?

Alector, Inc. (ALEC) had negative free cash flow of $173.2M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in ALEC back in 2016?

Total return calculator · dividends reinvested · 10+ years of data

See returns →