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VYGRVoyager Therapeutics, Inc.
$3.78$228M
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Voyager Therapeutics, Inc. (VYGR) Financial Ratios

Latest Ratios: P/E Ratio -1.9x · EV/EBITDA N/A · ROE -48.3%. (2013–2025 historical series)

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly

VYGR Valuation Multiples

Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Market Cap$228M$231M$327M$376M$234M$102M$267M$501M$301M$445M$322M
Enterprise Value$200M$202M$299M$328M$158M$29M$210M$449M$255M$413M$286M
P/E Ratio →-1.85——2.84——7.30————
P/S Ratio5.665.714.091.505.722.731.564.8039.5643.9022.67
P/B Ratio1.131.181.091.593.961.071.735.036.493.322.37
P/FCF———5.04———12.23———
P/OCF———4.83———10.29———

P/E links to full P/E history page with 30-year chart

VYGR EV Ratios

Enterprise-value multiples — capital-structure-neutral measures of total business value

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
EV / Revenue—5.003.741.313.870.771.234.3033.4140.7920.09
EV / EBITDA———2.59——6.74————
EV / EBIT———2.69——7.68————
EV / FCF———4.39———10.96———

VYGR Profitability

Margins and return-on-capital ratios measuring operating efficiency

Margins

Full margin charts and quarterly trend are on the Earnings History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Gross Margin100.0%100.0%100.0%63.1%-36.3%-97.2%36.4%-14.7%-751.9%-514.3%-197.1%
Operating Margin-326.6%-326.6%-104.1%48.8%-124.3%-196.8%16.0%-49.5%-1195.6%-709.1%-290.4%
Net Profit Margin-296.5%-296.5%-81.3%52.9%-113.4%-190.3%21.5%-41.8%-1158.8%-697.6%-282.7%

Return on Capital

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
ROE-48.3%-48.3%-24.3%89.6%-60.2%-57.1%28.9%-59.7%-97.8%-52.4%-26.4%
ROA-37.1%-37.1%-17.5%51.8%-26.3%-31.3%11.9%-16.4%-48.8%-37.8%-19.2%
ROIC-45.0%-45.0%-27.2%107.0%-1528.8%-92.6%28.3%-164.1%-133.8%-53.4%-26.1%
ROCE-46.3%-46.3%-26.4%65.3%-44.3%-39.0%10.7%-24.4%-58.0%-41.7%-21.7%

VYGR Leverage & Debt

Solvency and debt-coverage ratios — lower is generally safer

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Debt / Equity0.190.190.150.090.390.460.310.34———
Debt / EBITDA———0.16——1.53————
Net Debt / Equity—-0.15-0.09-0.21-1.28-0.77-0.37-0.52-1.01-0.24-0.27
Net Debt / EBITDA———-0.38——-1.82————
Debt / FCF———-0.65———-1.27———
Interest Coverage——————————-42.31

Net cash position: cash ($65M) exceeds total debt ($36M)

VYGR Liquidity & Efficiency

Short-term solvency ratios and asset-utilisation metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Current Ratio7.647.645.564.961.722.687.394.015.1310.8112.95
Quick Ratio7.647.645.564.961.722.687.393.984.9710.6912.84
Cash Ratio7.407.405.363.581.642.606.773.704.9210.6312.64
Asset Turnover—0.160.200.710.260.190.650.290.040.050.08
Inventory Turnover———————54.3812.6933.6527.72
Days Sales Outstanding—15.9220.49123.305.707.3017.0965.389.63—59.11

VYGR Shareholder Yields

Earnings, FCF, buyback, and dividend yields — total returns to shareholders

Dividends

Full dividend history and growth charts are on the Dividend History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Dividend Yield———————————
Payout Ratio———————————

Total Shareholder Return Metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Earnings Yield———35.2%——13.7%————
FCF Yield———19.8%———8.2%———
Buyback Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.3%0.0%0.0%
Total Shareholder Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.3%0.0%0.0%
Shares Outstanding—$59M$58M$45M$38M$38M$37M$36M$32M$27M$25M

Key Metrics

Growth RegimeMixed
ProfitabilityNegative
Balance SheetVulnerable
Cash FlowBurning
Top Statement Risk

Liquidity and Milestone Dependency

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2026Q1)

Market Pricing Reflects Platform Uncertainty

Based on reported figures, Voyager’s P/S ratio of 5.37 suggests that investors are pricing the company as a speculative platform play rather than a traditional biotech, with valuation heavily dependent on the perceived future optionality of the TRACER capsid technology rather than current earnings.

The lack of a meaningful P/E or EV/EBITDA multiple underscores the company's pre-commercial status and reliance on non-recurring licensing revenue. Investors should monitor whether this premium holds as the company shifts toward capital-intensive internal clinical development, which may compress valuation multiples if milestone progress stalls.

Capital Efficiency Deteriorating Amidst Investment

According to recent financial statements, Voyager’s ROIC has trended into negative territory, reaching -13.7% in 2026Q1, which indicates that the company is currently destroying shareholder value as it aggressively deploys capital into its internal Tau and SOD1 programs without offsetting commercial returns.

The sharp decline from the positive returns observed in 2023Q4 highlights the transition from a partnership-funded model to a more capital-intensive internal development phase. This trend warrants further investigation into whether the current R&D spend will eventually yield proprietary assets capable of generating superior long-term returns on invested capital.

Working Capital Volatility Masks Inefficiency

As reported in financial statements, the company's asset turnover ratio remains extremely low at 0.01 in 2026Q1, reflecting a structural inability to generate meaningful revenue from its current asset base, which is typical for a firm in the early stages of clinical-stage biotechnology development.

The erratic nature of the cash conversion cycle, driven by lumpy milestone payments, makes traditional efficiency metrics less useful for assessing operational health. Investors should focus on the burn rate relative to the remaining cash runway rather than standard working capital turnover ratios, which are distorted by the licensing model.

Liquidity Buffer Nearing Critical Thresholds

Based on the 2026Q1 balance sheet, the current ratio of 8.42 appears deceptively strong, yet it masks a rapidly depleting cash position that has fallen significantly from prior periods, leaving the company increasingly vulnerable to liquidity shocks if new partnership milestones are not achieved in the near term.

While the high current ratio suggests an ability to cover short-term obligations, the lack of recurring revenue means that the company is essentially consuming its own liquidity to fund operations. This position appears precarious, and the company may face significant dilution risk if it cannot secure additional non-dilutive funding or partnership capital.

Misapplication of Traditional Revenue Multiples

As indicated by the financial data, the P/S ratio is the most commonly misapplied metric for Voyager, as it fails to distinguish between high-quality recurring product sales and the lumpy, non-recurring licensing income that characterizes the company's current financial performance and distorts valuation comparisons.

Using P/S to value Voyager obscures the underlying volatility of its business model, as a single milestone payment can artificially inflate revenue and compress the multiple. Analysts should instead utilize a risk-adjusted net present value (rNPV) approach for the pipeline or focus on the cash-burn-to-runway ratio to better assess the company's true economic viability.

Download Financial Ratios Data

Includes 30+ ratios · 13 years · Updated daily

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VYGR — Frequently Asked Questions

Quick answers to the most common questions about buying VYGR stock.

What is Voyager Therapeutics, Inc.'s P/E ratio?

Voyager Therapeutics, Inc.'s current P/E ratio is -1.9x. The historical average is 5.1x.

What is Voyager Therapeutics, Inc.'s ROE?

Voyager Therapeutics, Inc.'s return on equity (ROE) is -48.3%. The historical average is -31.1%.

Is VYGR stock overvalued?

Based on historical data, Voyager Therapeutics, Inc. is trading at a P/E of -1.9x. Compare with industry peers and growth rates for a complete picture.

What are Voyager Therapeutics, Inc.'s profit margins?

Voyager Therapeutics, Inc. has 100.0% gross margin and -326.6% operating margin.