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SKYESkye Bioscience, Inc.
$0.70$25M
Overview & Verdict
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SKYE logoSkye Bioscience, Inc.(SKYE)Earnings, Financials & Key Ratios

SKYE•NASDAQ
$0.70
Price updated Jul 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOphthalmology Therapies and Delivery
AboutSkye Bioscience, Inc., a biopharmaceutical company, discovers, develops, and commercializes cannabinoid-based molecules for the treatment of infectious diseases. The company's lead product candidate is SBI-100, which is in Phase I trials for the treatment of glaucoma and ocular hypertension. It is also developing SBI-200 that is in preclinical trials to treat and manage various eye diseases, including uveitis, dry eye syndrome, macular degeneration and diabetic retinopathy. The company was formerly known as Emerald Bioscience, Inc. and changed its name to Skye Bioscience, Inc. in January 2021. Skye Bioscience, Inc. was founded in 2012 and is headquartered in San Diego, California.Show more
  • Revenue$0
  • EBITDA-$57M-92.1%
  • Net Income-$56M-110.5%
  • EPS (Diluted)-1.41-93.2%
  • ROE-126.85%-57.6%

SKYE Price & Volume

Skye Bioscience, Inc. (SKYE) stock price & volume — 10-year historical chart

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Clinical Development Costs Threaten Capital Liquidity Position

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Imminent liquidity exhaustion

Key Thesis Takeaways

  • Skye Bioscience remains a high-risk, pre-revenue clinical-stage entity entirely dependent on external financing to advance its metabolic pipeline, specifically the Nimacimab program.
  • The company's financial trajectory is characterized by aggressive capital consumption, with R&D expenses peaking at $14.3 million in 2025Q2, which continues to erode the equity base and total assets.
  • Investors should monitor the critical liquidity risk, as the current cash balance of $8.1 million as of 2026Q1 appears insufficient to sustain long-term clinical trial operations without further dilutive capital raises.

Verdict Logic

the company faces imminent liquidity exhaustion with a cash position of only $8.1 million as of 2026Q1, which is inadequate to support the ongoing high-cost clinical development of its metabolic pipeline.

SKYE Growth Metrics

Skye Bioscience, Inc. (SKYE) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-75.59%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-75.61%

Return on Capital

10 Years-652.22%
5 Years-758.77%
3 Years-781.81%
Last Year-131.39%

SKYE Recent Earnings

Skye Bioscience, Inc. (SKYE) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 4/12 qtrs (40%)
Q2 2026Latest
May 12, 2026
Metric
Actual
Est
EPS
$0.32-10.3%
$0.29
Rev
—
—
Q2 2026
Mar 10, 2026
Metric
Actual
Est
EPS
$0.36-21.2%
$0.30
Rev
—
—
Q4 2025
Nov 10, 2025
Metric
Actual
Est
EPS
$0.32+3.0%
$0.33
Rev
—
—
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.44-29.4%
$0.34
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 12, 2026
$0.32vs $0.29-10.3%
—
Q2 2026Mar 10, 2026
$0.36vs $0.30-21.2%
—
Q4 2025Nov 10, 2025
$0.32vs $0.33+3.0%
—
Q3 2025Aug 7, 2025
$0.44vs $0.34-29.4%
—
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Skye Bioscience, Inc. (SKYE)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
SKYE logoSKYESkye Bioscience, Inc.Current
$0.70$24.72M-0.50——-126.85%—
ATAI logoATAIAtai Beckley N.V
$5.19$1.91B-1.781227.6%-19019.44%-366.21%—
CMPS logoCMPSCOMPASS Pathways plc
$12.99$1.25B-4.22——-151.02%—
MNMD logoMNMDMind Medicine (MindMed) Inc.
$20.69$2.04B-10.04——-102.48%—
SNDL logoSNDLSNDL Inc.
$1.30$336.96M-30.792.82%-1.17%-1%—
CRBP logoCRBPCorbus Pharmaceuticals Holdings, Inc.
$9.38$117.58M-1.59——-70.89%—

Compare SKYE vs Peers

Skye Bioscience, Inc. (SKYE) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ATAI

Most directly comparable listed peer for SKYE.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare SKYE against a more recognizable public peer.

Peer Set

Compare Top 5

vs ATAI, CMPS, MNMD, SNDL

SKYE SEC Filings & Documents

Skye Bioscience, Inc. (SKYE) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 15, 2026·SEC

Material company update

Apr 3, 2026·SEC

Material company update

Mar 19, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 10, 2026·SEC

FY 2025

Mar 20, 2025·SEC

FY 2024

Mar 22, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 11, 2026·SEC

FY 2025

Nov 10, 2025·SEC

FY 2025

Aug 7, 2025·SEC

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SKYE Frequently Asked Questions

Skye Bioscience, Inc. (SKYE) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is SKYE profitable?

Skye Bioscience, Inc. (SKYE) reported a net loss of $57.3M for fiscal year 2025.

Dividend & Returns
What is SKYE's return on equity?

Skye Bioscience, Inc. (SKYE) has a return on equity (ROE) of -126.8%. Negative ROE indicates the company is unprofitable.

What is Skye Bioscience, Inc.'s free cash flow?

Skye Bioscience, Inc. (SKYE) had negative free cash flow of $42.4M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in SKYE back in 2012?

Total return calculator · dividends reinvested · 14+ years of data

See returns →