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SCYXSCYNEXIS, Inc.
$4.61$29M
Overview & Verdict
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SCYX logoSCYNEXIS, Inc.(SCYX)Earnings, Financials & Key Ratios

SCYX•NASDAQ
$4.61
Price updated Jul 7, 2026
SectorHealthcareIndustrySpecialty & Generic PharmaSub-IndustryTherapy-focused branded biopharma
AboutSCYNEXIS, Inc., a biotechnology company, develops products for the treatment fungal infections in the United States. It offers BREXAFEMME (ibrexafungerp tablets) for the treatment of vulvovaginal candidiasis (VVC). The company is developing its lead product candidate, Ibrexafungerp, as a novel oral and intravenous drug for the treatment of various fungal infections, including recurrent VVC, invasive aspergillosis, invasive candidiasis, and refractory invasive fungal infections; and ibrexafungerp that has completed Phase 3 CANDLE study for the prevention of recurrent (VVC). It has research collaborations with Merck Sharp & Dohme Corp., Hansoh (Shanghai) Health Technology Co., Ltd., Jiangsu Hansoh Pharmaceutical Group Company Limited, and R-Pharm, CJSC to develop and commercialize rights for ibrexafungerp. The company was formerly known as SCYNEXIS Chemistry & Automation, Inc. and changed its name to SCYNEXIS, Inc. in June 2002. SCYNEXIS, Inc. was incorporated in 1999 and is headquartered in Jersey City, New Jersey.Show more
  • Revenue$21M+449.9%
  • EBITDA-$16M+55.5%
  • Net Income-$9M+59.6%
  • EPS (Diluted)-1.36+61.4%
  • Gross Margin100%
  • EBITDA Margin-76.51%+91.9%
  • Operating Margin-78.03%+92.1%
  • Net Margin-41.79%+92.6%
  • ROE-16.48%+50.4%

SCYX Price & Volume

SCYNEXIS, Inc. (SCYX) stock price & volume — 10-year historical chart

Loading chart...

Erratic Milestone Revenue Masks Deep Operational Fragility

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Binary regulatory manufacturing failure

Key Thesis Takeaways

  • SCYNEXIS faces a precarious outlook as its commercial strategy for BREXAFEMME remains unproven, evidenced by a total revenue collapse to zero in 2026Q1.
  • The company's reliance on lumpy, non-recurring milestone payments creates extreme earnings volatility, while a $406.4M accumulated deficit highlights years of persistent operational losses.
  • Investors should remain cautious as the firm struggles to transition from a milestone-dependent model to a sustainable, recurring revenue-generating pharmaceutical entity.

Verdict Logic

the company's inability to maintain consistent commercial revenue, highlighted by the 2026Q1 revenue drop to zero, suggests significant and potentially insurmountable market adoption hurdles.

SCYX Growth Metrics

SCYNEXIS, Inc. (SCYX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years55.02%
5 Years-
3 Years59.35%
TTM673.54%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM9.5%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM23.87%

Return on Capital

10 Years-52.7%
5 Years-30.52%
3 Years3.78%
Last Year-26.83%

SCYX Recent Earnings

SCYNEXIS, Inc. (SCYX) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (67%)●Beat Revenue 6/12 qtrs (55%)
Q2 2026Latest
May 11, 2026
Metric
Actual
Est
EPS
$0.42-320.0%
$0.10
Rev
—
$77,000
Q2 2026
Mar 4, 2026
Metric
Actual
Est
EPS
$0.25+97.3%
$0.13
Rev
$19M+130.2%
$8M
Q4 2025
Nov 5, 2025
Metric
Actual
Est
EPS
$0.17+19.0%
$0.21
Rev
$334,000-95.9%
$8M
Q3 2025
Aug 13, 2025
Metric
Actual
Est
EPS
$0.14+39.1%
$0.23
Rev
$1M+785.7%
$154,000
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 11, 2026
$0.42vs $0.10-320.0%
—vs $77,000
Q2 2026Mar 4, 2026
$0.25vs $0.13+97.3%
$19Mvs $8M+130.2%
Q4 2025Nov 5, 2025
$0.17vs $0.21+19.0%
$334,000vs $8M-95.9%
Q3 2025Aug 13, 2025
$0.14vs $0.23+39.1%
$1Mvs $154,000+785.7%
Based on last 12 quarters of dataView full earnings history →

Latest SCYX News

Recent stock market news and headlines for SCYNEXIS, Inc. (SCYX)

GlobeNewsWire·Jun 30, 2026
SCYNEXIS Initiates Phase 1 Study of SCY-770, a Novel AMPK Activator for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)

JERSEY CITY, N.J., June 30, 2026 (GLOBE NEWSWIRE) -- SCYNEXIS, Inc. (NASDAQ: SCYX), a clinical-stage biotechnology company advancing novel therapies for severe rare diseases, today announced initiation of a Phase 1 study of SCY-770, a first-in-class, potent and direct AMP-activated protein kinase (AMPK) activator.

Peers Comparison

Key metrics vs top competitors for SCYNEXIS, Inc. (SCYX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
SCYX logoSCYXSCYNEXIS, Inc.Current
$4.61$28.99M-3.39449.95%-41.79%-16.48%—
AGIO logoAGIOAgios Pharmaceuticals, Inc.
$44.01$2.62B-6.1848.03%-639.84%-34.11%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$323.95$9.36B-24.03-100%—-43.02%—
CDTX logoCDTXCidara Therapeutics, Inc.
$221.38$6.96B-8.28-94.52%—-43.74%—
ATXS logoATXSAstria Therapeutics, Inc.
$12.58$718.13M-7.49—-17567.99%-53.17%—
GILD logoGILDGilead Sciences, Inc.
$136.36$169.3B20.112.39%30.99%42.33%—

Compare SCYX vs Peers

SCYNEXIS, Inc. (SCYX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs AGIO

Most directly comparable listed peer for SCYX.

Scale Benchmark

vs MRK

Larger-name benchmark to compare SCYX against a more recognizable public peer.

Peer Set

Compare Top 5

vs AGIO, PRAX, CDTX, ATXS

SCYX SEC Filings & Documents

SCYNEXIS, Inc. (SCYX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 29, 2026·SEC

Material company update

May 22, 2026·SEC

Material company update

Apr 20, 2026·SEC

10-K Annual Reports

5
FY 2026

Mar 4, 2026·SEC

FY 2025

Mar 12, 2025·SEC

FY 2024

Mar 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 11, 2026·SEC

FY 2025

Nov 5, 2025·SEC

FY 2025

Aug 13, 2025·SEC

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SCYX Frequently Asked Questions

SCYNEXIS, Inc. (SCYX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is SCYNEXIS, Inc.'s revenue?

SCYNEXIS, Inc. (SCYX) reported $20.3M in revenue for fiscal year 2025. This represents a 21% increase from $16.8M in 2012.

How fast is SCYNEXIS, Inc. growing?

SCYNEXIS, Inc. (SCYX) grew revenue by 449.9% over the past year. This is strong growth.

Is SCYX profitable?

SCYNEXIS, Inc. (SCYX) reported a net loss of $24.5M for fiscal year 2025.

Dividend & Returns
What is SCYX's return on equity?

SCYNEXIS, Inc. (SCYX) has a return on equity (ROE) of -16.5%. Negative ROE indicates the company is unprofitable.

What is SCYNEXIS, Inc.'s free cash flow?

SCYNEXIS, Inc. (SCYX) had negative free cash flow of $5.9M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in SCYX back in 2012?

Total return calculator · dividends reinvested · 14+ years of data

See returns →