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RGENRepligen Corporation
$139.83$7.9B
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  4. Financial Ratios

Repligen Corporation (RGEN) Financial Ratios

Latest Ratios: P/E Ratio 162.6x · EV/EBITDA 57.9x · ROE 2.4%. (1996–2025 historical series)

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly

RGEN Valuation Multiples

Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Market Cap$7.9B$9.3B$8.1B$10.1B$9.7B$15.2B$10.3B$4.6B$2.4B$1.4B$1.1B
Enterprise Value$8.0B$9.4B$8.0B$10.1B$9.6B$14.9B$9.9B$4.3B$2.3B$1.3B$1.0B
P/E Ratio →162.59190.53—285.4052.26118.23172.64210.23142.5450.3990.65
P/S Ratio10.6812.5512.6916.0312.1422.6228.2016.8412.3610.0610.05
P/B Ratio3.764.404.085.165.098.676.754.293.902.406.23
P/FCF83.9998.7056.51135.28251.12317.67284.65103.30128.02118.39328.83
P/OCF67.1778.9345.9188.9856.53127.43164.9167.7273.1881.39139.73

P/E links to full P/E history page with 30-year chart

RGEN EV Ratios

Enterprise-value multiples — capital-structure-neutral measures of total business value

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
EV / Revenue—12.7212.5815.9712.0122.2626.9915.8611.899.539.61
EV / EBITDA57.9167.90155.1275.4534.1872.5791.2370.3355.2655.0347.14
EV / EBIT134.45109.78—170.5343.7090.57138.55120.9488.8098.3252.27
EV / FCF—100.0256.01134.75248.53312.69272.4797.28123.19112.18314.28

RGEN Profitability

Margins and return-on-capital ratios measuring operating efficiency

Margins

Full margin charts and quarterly trend are on the Earnings History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Gross Margin47.1%47.1%43.3%44.0%56.9%58.3%53.1%51.1%55.7%52.5%54.9%
Operating Margin8.1%8.1%-5.5%7.5%28.0%24.9%22.2%14.8%13.4%9.9%15.3%
Net Profit Margin6.6%6.6%-4.0%5.6%23.2%19.1%16.4%7.9%8.6%20.1%11.2%

Return on Capital

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
ROE2.4%2.4%-1.3%1.8%10.2%7.8%4.6%2.6%2.8%7.5%8.0%
ROA1.7%1.7%-0.9%1.3%7.6%6.0%3.6%2.8%12.8%13.9%5.4%
ROIC2.2%2.2%-1.4%1.9%10.1%9.7%6.5%4.6%3.7%3.3%14.0%
ROCE2.2%2.2%-1.3%2.0%10.9%9.4%5.5%5.9%49.6%7.7%8.1%

RGEN Leverage & Debt

Solvency and debt-coverage ratios — lower is generally safer

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Debt / Equity0.330.330.350.360.220.210.180.250.170.170.56
Debt / EBITDA4.994.9913.345.321.501.782.544.322.484.064.47
Net Debt / Equity—0.06-0.04-0.02-0.05-0.14-0.29-0.25-0.15-0.13-0.28
Net Debt / EBITDA0.900.90-1.38-0.30-0.36-1.16-4.08-4.35-2.16-3.05-2.18
Debt / FCF—1.32-0.50-0.53-2.59-4.98-12.18-6.02-4.82-6.21-14.55
Interest Coverage3.693.69-0.285.9174.0012.965.883.813.872.135.10

RGEN Liquidity & Efficiency

Short-term solvency ratios and asset-utilisation metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Current Ratio8.378.378.416.742.472.482.8313.282.129.638.74
Quick Ratio7.127.127.285.511.881.992.5312.151.808.087.57
Cash Ratio5.655.655.974.561.541.612.2510.941.496.896.73
Asset Turnover—0.250.220.220.320.280.190.191.391.170.36
Inventory Turnover2.292.292.521.751.451.511.812.412.031.721.91
Days Sales Outstanding—78.4177.1671.6752.9463.9271.1458.9867.2671.6855.98

RGEN Shareholder Yields

Earnings, FCF, buyback, and dividend yields — total returns to shareholders

Dividends

Full dividend history and growth charts are on the Dividend History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Dividend Yield———————————
Payout Ratio———————————

Total Shareholder Return Metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Earnings Yield0.6%0.5%—0.4%1.9%0.8%0.6%0.5%0.7%2.0%1.1%
FCF Yield1.2%1.0%1.8%0.7%0.4%0.3%0.4%1.0%0.8%0.8%0.3%
Buyback Yield0.0%0.0%0.0%0.1%0.0%0.0%0.0%0.0%0.0%0.0%0.0%
Total Shareholder Yield0.0%0.0%0.0%0.1%0.0%0.0%0.0%0.0%0.0%0.0%0.0%
Shares Outstanding—$57M$56M$56M$57M$57M$54M$49M$45M$39M$34M

Key Metrics

Growth RegimeAccelerating
ProfitabilityStrained
Balance SheetHealthy
Cash FlowImproving
Top Statement Risk

Bioprocessing inventory destocking cycles

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2026Q1)

Premium Valuation Reflects Growth Expectations

Based on current market data, Repligen trades at a forward P/E of 73.36, a multiple that appears to price in a significant recovery in organic growth rates that exceeds the more modest expectations typically assigned to its diversified life science tools peers in the current environment.

The elevated P/E and EV/EBITDA multiples suggest that investors are paying a substantial premium for the company's 'spec-in' moat and potential for long-term margin expansion. However, this valuation warrants caution, as it implies a high degree of confidence in the company's ability to return to historical growth trajectories while navigating ongoing industry-wide destocking headwinds.

Capital Efficiency Remains Under Pressure

As reported in recent financial statements, Repligen's ROIC has struggled to gain traction, hovering at a marginal 0.6% in 2026Q1, which indicates that the company's recent capital allocation and acquisition strategy have yet to generate returns that exceed the firm's likely cost of capital.

The persistent weakness in ROIC suggests that the integration of past acquisitions and the current overhead structure are diluting the efficiency of invested capital. Investors should monitor whether management can improve asset utilization and margin profiles to drive a meaningful recovery in returns, as current levels remain well below historical performance.

Working Capital Dynamics Impacting Turnover

According to quarterly filings, Repligen's asset turnover remains constrained at 0.07, reflecting a business model that is currently burdened by significant inventory levels and a complex manufacturing footprint that has yet to fully normalize following the post-pandemic demand recalibration observed across the bioprocessing sector.

The elevated days inventory outstanding (DIO) figures suggest that the company is still managing the tail end of inventory accumulation, which continues to weigh on overall working capital efficiency. A sustained improvement in the cash conversion cycle will be necessary to demonstrate that the company can effectively convert its specialized product pipeline into consistent cash flow.

Liquidity Buffers Support Operational Stability

Based on the latest balance sheet data, Repligen maintains a robust current ratio of 9.20, providing a substantial liquidity cushion that appears more than adequate to navigate potential supply chain volatility and fund ongoing R&D initiatives without the immediate need for external financing or debt restructuring.

This strong liquidity position serves as a critical defensive feature, allowing the company to maintain its strategic focus despite the recent volatility in operating margins. The high quick ratio further confirms that the firm's liquidity is not overly dependent on the immediate liquidation of inventory, which is a prudent stance given the current industry environment.

Misapplication of P/E Multiples

The P/E ratio is frequently misapplied to Repligen, as it obscures the significant impact of non-cash amortization charges and stock-based compensation that arise from the company's aggressive acquisition strategy, thereby failing to capture the true underlying cash-generating potential of the core bioprocessing business.

Analysts should prioritize EV/EBITDA or free cash flow metrics to better assess the company's operational performance, as these measures are less distorted by the accounting nuances of recent M&A activity. Relying solely on P/E may lead to an inaccurate assessment of the company's valuation relative to its actual cash-generating capacity.

Download Financial Ratios Data

Includes 30+ ratios · 30 years · Updated daily

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RGEN — Frequently Asked Questions

Quick answers to the most common questions about buying RGEN stock.

What is Repligen Corporation's P/E ratio?

Repligen Corporation's current P/E ratio is 162.6x. The historical average is 88.0x. This places it at the 79th percentile of its historical range.

What is Repligen Corporation's EV/EBITDA?

Repligen Corporation's current EV/EBITDA is 57.9x. This enterprise value multiple compares the company's total value (equity + debt - cash) to its EBITDA. The historical average is 49.6x.

What is Repligen Corporation's ROE?

Repligen Corporation's return on equity (ROE) is 2.4%. The historical average is -4.8%.

Is RGEN stock overvalued?

Based on historical data, Repligen Corporation is trading at a P/E of 162.6x. This is at the 79th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.

What are Repligen Corporation's profit margins?

Repligen Corporation has 47.1% gross margin and 8.1% operating margin.

How much debt does Repligen Corporation have?

Repligen Corporation's Debt/EBITDA ratio is 5.0x, indicating high leverage. A ratio above 4x may signal elevated financial risk.