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PRAXPraxis Precision Medicines, Inc.
$313.50$9.1B
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Praxis Precision Medicines, Inc. (PRAX) Financials

8Y historyFree accessUpdated daily

The company remains in a pre-revenue state with quarterly revenue growth at -100% and operating losses widening to $105.9 million in 2026Q1 due to aggressive R&D spending.

PRAX Income Statement

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly
MetricTTMDec'25Dec'24Dec'23Dec'22Dec'21Dec'20Dec'19Dec'18
Sales/Revenue008.55M2.45M00000
Revenue Growth %-100%-100%249.53%------
Cost of Goods Sold128.84M140K152.41M86.77M154.44M00679K1K
COGS % of Revenue--1781.98%3545.81%-----
Gross Profit-128.84M-140K-143.86M-84.32M-154.44M00-679K-1K
Gross Margin %---1681.98%-3445.81%-----
Gross Profit Growth %-99.9%-70.61%45.4%--100%-67800%-
Operating Expenses228.53M326.06M56.3M42.05M60.55M167.33M61.97M35.79M22.72M
OpEx % of Revenue--658.31%1718.59%-----
Selling, General & Admin73.03M59.08M56.3M42.05M59.55M47.08M16.99M6.23M3.9M
SG&A % of Revenue--658.31%1718.59%-----
Research & Development284.3M267.12M152.41M86.77M155.04M120.26M44.98M29.56M18.82M
R&D % of Revenue--1781.98%3545.81%-----
Other Operating Expenses-2M0-152.41M-86.77M-154.04M0000
Operating Income-357.33M-326.2M-200.16M-126.37M-214.99M-167.33M-61.97M-35.79M-22.72M
Operating Margin %---2340.29%-5164.41%-----
Operating Income Growth %--62.96%-58.39%41.22%-28.48%-170.03%-73.15%-57.53%-
EBITDA-357.2M-326.06M-199.81M-125.94M-214.57M-167.15M-61.92M-35.11M-22.72M
EBITDA Margin %---2336.1%-5146.75%-----
EBITDA Growth %-53.49%-63.19%-58.65%41.3%-28.37%-169.95%-76.35%-54.55%-
D&A (Non-Cash Add-back)132K140K358K432K419K182K50K679K1K
EBIT-352.9M-303.27M-200.16M-126.37M-213.99M-167.33M-61.97M-35.6M-26.27M
Net Interest Income18.24M22.93M17.35M000140K193K-35K
Interest Income18.24M22.93M17.35M000140K193K92K
Interest Expense00000000127K
Other Income/Expense30.8M22.93M17.35M3.1M957K271K140K193K-3.68M
Pretax Income-326.53M-303.27M-182.82M-123.28M-214.03M-167.06M-61.83M-35.6M-26.4M
Pretax Margin %---2137.48%-5037.88%-----
Income Tax000000-8K-84K133K
Effective Tax Rate %0%0%0%0%0%0%0.01%0.24%-0.5%
Net Income-326.53M-303.27M-182.82M-123.28M-214.03M-167.06M-61.82M-35.51M-26.54M
Net Margin %---2137.48%-5037.88%-----
Net Income Growth %-53.62%-65.88%-48.3%42.4%-28.11%-170.24%-74.08%-33.83%-
Net Income (Continuing)-326.53M-303.27M-182.82M-123.28M-214.03M-167.06M-61.82M-35.51M-26.54M
Discontinued Operations000000000
Minority Interest000000000
EPS (Diluted)-11.31-13.48-10.21-18.69-69.33-58.96-103.61-348.24-306.73
EPS Growth %-24.72%-32.03%45.37%73.04%-17.59%43.09%70.25%-13.53%-
EPS (Basic)--13.48-10.21-18.69-69.33-58.96-103.61-348.24-306.73
Diluted Shares Outstanding28.88M22.5M17.91M6.59M3.07M2.83M596.68K101.97K86.51K
Basic Shares Outstanding28.88M22.5M17.91M6.59M3.07M2.83M596.68K101.97K86.51K
Dividend Payout Ratio---------

Key Metrics

Growth RegimeContracting
ProfitabilityNegative
Balance SheetAdequate
Cash FlowBurning
Top Statement Risk

Binary Clinical Trial Outcomes

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2026Q1)

Revenue Absence Reflects Clinical Focus

As indicated by recent financial filings, Praxis has effectively transitioned to a pre-revenue state, with quarterly revenue growth consistently reporting at -100% since early 2025, underscoring the company's total reliance on non-recurring milestone payments rather than any sustainable commercial product sales or recurring service revenue streams.

The lack of consistent top-line growth is characteristic of a clinical-stage biotech firm where revenue is tied to sporadic licensing events rather than operational scale. Investors should interpret this trajectory as a reflection of the company's current focus on R&D milestones rather than market penetration.

Escalating R&D Driven Burn Rate

Based on reported income statements, R&D expenditures have surged to $78.0 million in 2026Q1, representing a significant expansion in clinical trial activity that continues to outpace any potential revenue generation and places substantial pressure on the firm's existing cash reserves to fund ongoing development programs.

The cost structure is dominated by high-intensity clinical trial operations, which appear to be the primary driver of the company's widening operating losses. This expense profile suggests that management is prioritizing the acceleration of late-stage assets, though it necessitates a high degree of capital efficiency to avoid premature liquidity constraints.

Operating Leverage Remains Deeply Negative

According to historical income statement data, the company's operating losses have widened significantly, reaching $105.9 million in 2026Q1, which demonstrates a lack of operating leverage as R&D investments continue to scale without a corresponding increase in commercial revenue or operational efficiencies to offset the burn.

The absence of positive operating margins indicates that the firm is currently in a pure investment phase where overhead and trial costs are not yet supported by commercial activity. This trend suggests that until a lead asset reaches the market, the company will remain entirely dependent on external financing to sustain its operations.

Sustainability of Current Cash Runway

Financial statements reveal that the company's net loss has consistently deepened, with 2026Q1 net losses reaching $92.6 million, raising concerns regarding the long-term sustainability of the current cash runway in the absence of a commercial partnership or a successful, non-dilutive licensing deal for lead assets.

While the current cash position provides a temporary buffer, the persistent and increasing quarterly losses suggest that the company may face significant dilution risks if clinical timelines are extended or if trial costs continue to escalate. Investors should monitor the relationship between the current burn rate and the timing of upcoming clinical data readouts as a primary indicator of future capital needs.

PRAX — Frequently Asked Questions

Quick answers to the most common questions about buying PRAX stock.

What was Praxis Precision Medicines, Inc.'s (PRAX) revenue in 2025?

For fiscal year 2025, Praxis Precision Medicines, Inc. (PRAX) reported total revenue of $0.0M.

Is Praxis Precision Medicines, Inc. (PRAX) profitable?

Praxis Precision Medicines, Inc. (PRAX) reported a net loss of $303.3M for the fiscal year ending 2025.