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MTSRMetsera, Inc.
$70.50$7.4B
Overview & Verdict
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MTSR logoMetsera, Inc.(MTSR)Earnings, Financials & Key Ratios

MTSR•NASDAQ
$70.50
Price updated Jun 20, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryMetabolic and Obesity Therapies
AboutMetsera, Inc., a clinical-stage biotechnology company, develops injectable and oral nutrient stimulated hormone analog peptides to treat obesity, overweight, and related diseases. It develops MET-097i and MET-233i for the treatment of obesity and overweight; MET-233i/MET-097i; and MET-002, MET-224o, MET-067i, and MET-034i to treat disorders, such as diabetes and obesity. The company was incorporated in 2022 and is headquartered in New York, New York.Show more
  • Revenue$0
  • EBITDA-$225M-414.8%
  • Net Income-$209M-343.0%
  • EPS (Diluted)-2.03-113.7%
  • ROE-108.4%-126.2%

MTSR Price & Volume

Metsera, Inc. (MTSR) stock price & volume — 10-year historical chart

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Accelerating Clinical Investment Drives Significant Cash Burn

Investment Thesis • Updated 2025Q3

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Adequate
Cash Flow:Burning
Primary Risk:Clinical trial execution failure

Key Thesis Takeaways

  • Metsera is currently in a high-intensity development phase, prioritizing the advancement of its NuSH platform over near-term profitability.
  • While the company maintains a current ratio of 4.25, the rapid escalation of R&D spending to $63.7 million in 2025Q3 suggests a narrowing runway that may necessitate future capital raises.
  • Investors should monitor the clinical trial outcomes closely, as the current $116.2 million quarterly net loss reflects the substantial financial commitment required to bring its metabolic therapeutic pipeline to market.

Verdict Logic

the company's accelerating cash burn, which reached an $81.7 million operating outflow in 2025Q3, presents significant dilution risk for shareholders in the absence of near-term revenue generation.

MTSR Growth Metrics

Metsera, Inc. (MTSR) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-

Return on Capital

10 Years-56.92%
5 Years-56.92%
3 Years-56.92%
Last Year-84.47%

MTSR Recent Earnings

Metsera, Inc. (MTSR) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 0/4 qtrs (0%)
Q4 2025Latest
Nov 12, 2025
Metric
Actual
Est
EPS
$1.11-98.2%
$0.56
Rev
—
—
Q3 2025
Jul 28, 2025
Metric
Actual
Est
EPS
$0.66-0.3%
$0.66
Rev
—
—
Q2 2025
May 12, 2025
Metric
Actual
Est
EPS
$1.03-21.2%
$0.85
Rev
—
—
Q2 2025
Mar 26, 2025
Metric
Actual
Est
EPS
$3.52-340.0%
$0.80
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q4 2025LatestNov 12, 2025
$1.11vs $0.56-98.2%
—
Q3 2025Jul 28, 2025
$0.66vs $0.66-0.3%
—
Q2 2025May 12, 2025
$1.03vs $0.85-21.2%
—
Q2 2025Mar 26, 2025
$3.52vs $0.80-340.0%
—
Based on last 4 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Metsera, Inc. (MTSR)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
MTSR logoMTSRMetsera, Inc.Current
$70.50$7.43B-34.73——-108.4%—
VKTX logoVKTXViking Therapeutics, Inc.
$42.13$4.88B-13.21——-71.31%—
TERN logoTERNTerns Pharmaceuticals, Inc.
$52.95$4.77B-51.41——-20.02%—
GPCR logoGPCRStructure Therapeutics Inc.
$56.63$3.26B-23.60——-15.14%—
PEPG logoPEPGPepGen Inc.
$2.05$141.8M-0.97——-59.89%—
NVO logoNVONovo Nordisk A/S
$49.64$220.59B14.106.43%37.2%66.36%—

Compare MTSR vs Peers

Metsera, Inc. (MTSR) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs VKTX

Most directly comparable listed peer for MTSR.

Scale Benchmark

vs LLY

Larger-name benchmark to compare MTSR against a more recognizable public peer.

Peer Set

Compare Top 5

vs VKTX, TERN, GPCR, PEPG

MTSR SEC Filings & Documents

Metsera, Inc. (MTSR) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Nov 13, 2025·SEC

Material company update

Nov 10, 2025·SEC

Material company update

Nov 6, 2025·SEC

10-K Annual Reports

1
FY 2025

Mar 26, 2025·SEC

10-Q Quarterly Reports

3
FY 2025

Nov 12, 2025·SEC

FY 2025

Jul 28, 2025·SEC

FY 2025

May 12, 2025·SEC

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MTSR Frequently Asked Questions

Metsera, Inc. (MTSR) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is MTSR profitable?

Metsera, Inc. (MTSR) reported a net loss of $314.4M for fiscal year 2024.

Dividend & Returns
What is MTSR's return on equity?

Metsera, Inc. (MTSR) has a return on equity (ROE) of -108.4%. Negative ROE indicates the company is unprofitable.

What is Metsera, Inc.'s free cash flow?

Metsera, Inc. (MTSR) had negative free cash flow of $231.6M in fiscal year 2024, likely due to heavy capital investments.

What if you invested $1,000 in MTSR back in 2023?

Total return calculator · dividends reinvested · 3+ years of data

See returns →