LYEL trades 234.8% below Wall Street's consensus target of $47.00.
Last 12 months price action with 12-month analyst target path
The base valuation assumes LYEL achieves its forward estimates and maintains a stable P/E multiple of historical averagesx. This scenario reflects the blended consensus of 7 Wall Street analysts, balancing both positive catalysts and macroeconomic headwinds over the next 12 months.
As of July 7, 2026, Lyell Immunopharma, Inc. (LYEL) has a Wall Street consensus price target of $47.00, based on estimates from 7 covering analysts. With the stock currently trading at $14.04, this represents a potential upside of +234.8%. The company has a market capitalization of $328M.
Analyst price targets range from a low of $45.00 to a high of $49.00, representing a 9% spread in expectations. The median target of $47.00 aligns closely with the consensus average. The tight target dispersion indicates high conviction among analysts.
The current analyst consensus rating is Buy, with 3 analysts rating the stock as a Buy or Strong Buy,3 rating it Hold, and 1 rating it Sell or Strong Sell. The mixed ratings reflect uncertainty about near-term direction.
From a valuation perspective, LYEL trades at a trailing P/E of -0.9x. Analysts expect EPS to grow +31.8% over the next year.
| Company | Market Cap | Price | Target | Upside Potential | Rating | Fwd P/E | Analysts |
|---|---|---|---|---|---|---|---|
FATEFate Therapeutics, Inc. | $349M | $2.99 | $5.50 | +83.9% | Buy | — | 31 |
ADCTADC Therapeutics S.A. | $159M | $1.25 | $3.50 | +180.0% | Hold | — | 12 |
CABACabaletta Bio, Inc. | $491M | $3.01 | $16.33 | +442.5% | Buy | — | 12 |
TGTXTG Therapeutics, Inc. | $8.2B | $53.52 | $64.00 | +19.6% | Buy | 39.4x | 13 |
KYMRKymera Therapeutics, Inc. | $9.4B | $114.76 | $125.29 | +9.2% | Buy | — | 27 |
ALKTAlkami Technology, Inc. | $2.0B | $18.95 | $22.00 | +16.1% | Buy | 24.3x | 12 |
NKTRNektar Therapeutics | $1.4B | $73.15 | $149.60 | +104.5% | Buy | — | 33 |
IMVTImmunovant, Inc. | $7.9B | $38.60 | $45.00 | +16.6% | Buy | — | 23 |
RCUSArcus Biosciences, Inc. | $3.0B | $29.98 | $31.00 | +3.4% | Buy | — | 18 |
ILMNIllumina, Inc. | $29.5B | $194.33 | $156.27 | -19.6% | Buy | 37.1x | 50 |
Quick answers to the most common questions about buying LYEL stock.
The consensus Wall Street price target for LYEL is $47, representing 234.8% upside from the current price of $14.04. With 7 analysts covering the stock, this strong upside suggests significant value not yet reflected in today's share price.
LYEL has a consensus rating of "Buy" based on 7 Wall Street analysts. The rating breakdown is mixed, with 3 Hold ratings making up the largest segment. The consensus 12-month price target of $47 implies 234.8% upside from current levels.
LYEL's current price is $14.04 with a consensus target of $47 (234.8% implied move). Analyst estimates suggest the stock is undervalued at current levels.
The most bullish Wall Street analyst has a price target of $49 for LYEL, while the most conservative target is $45. The consensus of $47 represents the median expectation. These targets typically reflect 12-month expectations.
LYEL is moderately covered, with 7 analysts providing price targets and ratings. Of these, 0 have Strong Buy ratings, 3 have Buy ratings, 3 recommend Hold, and 1 have Sell or Strong Sell ratings. Higher analyst coverage generally indicates greater institutional interest and more reliable consensus estimates.
The 12-month LYEL stock forecast based on 7 Wall Street analysts shows a consensus price target of $47, with estimates ranging from $45 (bear case) to $49 (bull case). The median consensus rating is "Buy".
Wall Street analysts are very optimistic on LYEL, with a "Buy" consensus rating and $47 price target (234.8% upside). 3 of 7 analysts rate it Buy or Strong Buy. This information is for educational purposes only. Always conduct your own research, consider your financial situation, and consult a financial advisor before making investment decisions.
LYEL analyst price targets range from $45 to $49, a 9% tight range reflecting strong analyst consensus. Differences stem from varying assumptions about revenue growth, profit margins, competitive dynamics, and valuation multiples. The $47 consensus represents the middle ground.
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