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LNTHLantheus Holdings, Inc.
$102.82$6.7B
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Lantheus Holdings, Inc. (LNTH) Financial Ratios

Latest Ratios: P/E Ratio 30.2x · EV/EBITDA 16.6x · ROE 21.4%. (2012–2025 historical series)

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly

LNTH Valuation Multiples

Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Market Cap$6.7B$4.6B$6.4B$4.4B$3.6B$1.9B$730M$823M$618M$795M$281M
Enterprise Value$6.3B$4.2B$6.1B$4.3B$3.8B$2.0B$887M$924M$771M$987M$508M
P/E Ratio →30.1519.5220.5213.33127.40——25.9615.196.4510.49
P/S Ratio4.342.954.183.363.854.592.152.371.802.400.93
P/B Ratio6.464.185.895.348.054.201.427.188.7134.15—
P/FCF18.9112.8713.0016.8313.6746.67186.2014.1115.0621.366.65
P/OCF17.1611.6711.7714.2712.7836.1644.5410.2310.1014.525.66

P/E links to full P/E history page with 30-year chart

LNTH EV Ratios

Enterprise-value multiples — capital-structure-neutral measures of total business value

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
EV / Revenue—2.723.993.284.034.802.612.662.252.981.68
EV / EBITDA16.6311.0211.7310.0344.81—43.2714.219.8413.916.78
EV / EBIT20.3812.5813.579.88111.17——21.8811.5217.019.25
EV / FCF—11.8512.4016.4614.3148.89226.0515.8518.7826.5112.02

LNTH Profitability

Margins and return-on-capital ratios measuring operating efficiency

Margins

Full margin charts and quarterly trend are on the Earnings History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Gross Margin61.1%61.1%64.4%54.7%62.2%44.1%40.9%50.3%50.9%48.9%45.6%
Operating Margin20.2%20.2%29.8%28.1%3.9%-14.3%-1.2%14.9%18.8%15.6%18.7%
Net Profit Margin15.2%15.2%20.4%25.2%3.0%-16.8%-4.0%9.1%11.8%37.2%8.9%

Return on Capital

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
ROE21.4%21.4%32.8%51.7%6.2%-14.6%-4.3%34.1%85.9%529.8%—
ROA11.1%11.1%17.2%22.0%2.6%-8.2%-2.1%7.5%9.8%38.6%10.7%
ROIC30.6%30.6%45.3%41.0%4.6%-7.4%-0.7%17.6%22.0%23.2%32.6%
ROCE17.1%17.1%28.5%28.7%3.9%-7.8%-0.7%14.2%17.8%18.9%27.0%

LNTH Leverage & Debt

Solvency and debt-coverage ratios — lower is generally safer

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Debt / Equity0.000.000.570.761.300.410.461.703.7511.51—
Debt / EBITDA0.000.001.191.456.94—11.512.993.403.783.72
Net Debt / Equity—-0.33-0.27-0.120.380.200.300.892.168.24—
Net Debt / EBITDA-0.94-0.94-0.56-0.232.00—7.631.561.952.703.03
Debt / FCF—-1.01-0.59-0.370.642.2239.851.743.735.155.37
Interest Coverage16.8916.8922.9121.534.72-8.68-0.213.103.853.152.06

Net cash position: cash ($359M) exceeds total debt ($738000)

LNTH Liquidity & Efficiency

Short-term solvency ratios and asset-utilisation metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Current Ratio2.702.705.525.802.742.612.292.623.703.162.53
Quick Ratio2.512.515.235.452.592.221.842.173.082.602.13
Cash Ratio1.081.083.803.811.681.090.991.412.151.631.17
Asset Turnover—0.690.770.790.710.490.390.860.780.861.18
Inventory Turnover9.279.278.029.179.966.765.615.915.106.499.30
Days Sales Outstanding—84.9176.4480.0483.3076.6958.0745.7446.5144.3444.52

LNTH Shareholder Yields

Earnings, FCF, buyback, and dividend yields — total returns to shareholders

Dividends

Full dividend history and growth charts are on the Dividend History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Dividend Yield———————————
Payout Ratio———————————

Total Shareholder Return Metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Earnings Yield3.3%5.1%4.9%7.5%0.8%——3.9%6.6%15.5%9.5%
FCF Yield5.3%7.8%7.7%5.9%7.3%2.1%0.5%7.1%6.6%4.7%15.0%
Buyback Yield4.5%6.6%1.6%0.0%2.1%0.0%0.0%0.0%0.0%0.0%0.0%
Total Shareholder Yield4.5%6.6%1.6%0.0%2.1%0.0%0.0%0.0%0.0%0.0%0.0%
Shares Outstanding—$68M$72M$70M$71M$67M$54M$40M$40M$39M$33M

Key Metrics

Growth RegimeDecelerating
ProfitabilityModerate
Balance SheetFortress
Cash FlowStable
Top Statement Risk

Isotope supply chain dependency

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2026Q1)

Premium Valuation Reflects Growth Expectations

Based on current market data, Lantheus trades at a forward P/E of 20.53, which suggests that investors are pricing in a transition from high-growth diagnostic adoption to a more mature, steady-state earnings profile as the PSMA imaging market faces increasing competitive pressure from new entrants.

The current valuation multiple appears to be a premium relative to traditional specialty pharma, yet it remains tempered by the inherent risks of isotope supply chain volatility. Investors should monitor whether the forward EV/EBITDA of 8.24 accurately captures the potential for margin compression if reimbursement models shift toward bundled payments.

Capital Efficiency Trends Show Decay

According to historical financial data, the company's ROIC has trended downward from 14.5% in 2023Q4 to 5.8% in 2026Q1, indicating that recent capital deployments have struggled to generate the same level of incremental returns as the initial PYLARIFY commercialization phase observed in earlier periods.

This decline in capital efficiency warrants further investigation into whether the firm's recent M&A activity is diluting the returns of its core diagnostic franchise. The shift suggests that management may be entering a phase of diminishing marginal returns on invested capital as the competitive landscape for PSMA-targeting agents intensifies.

Working Capital Cycles Remain Stretched

As reported in quarterly filings, the cash conversion cycle has fluctuated near 97 days as of 2026Q1, reflecting the logistical complexity of managing radiopharmaceuticals with extremely short half-lives that necessitate rapid inventory turnover and precise coordination with hospital-based diagnostic centers across the United States.

The elevated DSO of 85 days suggests that the company may be facing extended payment terms from hospital systems, which could pressure liquidity if not managed effectively. This working capital profile is structurally different from traditional drug manufacturers, as the inventory must be moved almost immediately upon production to avoid total loss.

Debt-Free Status Provides Strategic Buffer

Based on the most recent balance sheet, Lantheus has achieved a debt-to-equity ratio of 0.00, providing a significant financial fortress that insulates the company from interest rate volatility and allows for continued investment in the therapeutic pipeline despite the current deceleration in top-line revenue growth.

This lack of leverage is a critical differentiator compared to peers, offering management the flexibility to navigate potential supply chain shocks or regulatory reimbursement adjustments without the burden of debt service. Investors should view this as a defensive moat that supports long-term operational stability in a capital-intensive industry.

Misapplication of Standard P/E Multiples

The P/E ratio is frequently misapplied to Lantheus because it fails to account for the high non-cash inventory write-offs and the unique 'use-it-or-lose-it' accounting nature of short-lived radiopharmaceuticals, which can create artificial volatility in reported net income that does not reflect true underlying cash generation.

Analysts should prioritize FCF-based metrics over P/E, as the latter obscures the company's ability to generate cash despite the accounting noise inherent in isotope distribution. Relying on P/E may lead to an incorrect assessment of the firm's earning power during periods of supply chain disruption or inventory obsolescence.

Download Financial Ratios Data

Includes 30+ ratios · 14 years · Updated daily

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LNTH — Frequently Asked Questions

Quick answers to the most common questions about buying LNTH stock.

What is Lantheus Holdings, Inc.'s P/E ratio?

Lantheus Holdings, Inc.'s current P/E ratio is 30.2x. The historical average is 29.9x. This places it at the 88th percentile of its historical range.

What is Lantheus Holdings, Inc.'s EV/EBITDA?

Lantheus Holdings, Inc.'s current EV/EBITDA is 16.6x. This enterprise value multiple compares the company's total value (equity + debt - cash) to its EBITDA. The historical average is 17.2x.

What is Lantheus Holdings, Inc.'s ROE?

Lantheus Holdings, Inc.'s return on equity (ROE) is 21.4%. This is above the typical threshold of 15-20% considered good for most companies. The historical average is 26.7%.

Is LNTH stock overvalued?

Based on historical data, Lantheus Holdings, Inc. is trading at a P/E of 30.2x. This is at the 88th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.

What are Lantheus Holdings, Inc.'s profit margins?

Lantheus Holdings, Inc. has 61.1% gross margin and 20.2% operating margin. Operating margin above 20% indicates strong pricing power and cost efficiency.

How much debt does Lantheus Holdings, Inc. have?

Lantheus Holdings, Inc.'s Debt/EBITDA ratio is 0.0x, indicating low leverage. A ratio below 2x is generally considered financially healthy.