Latest Ratios: P/E Ratio 30.2x · EV/EBITDA 16.6x · ROE 21.4%. (2012–2025 historical series)
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $6.7B | $4.6B | $6.4B | $4.4B | $3.6B | $1.9B | $730M | $823M | $618M | $795M | $281M |
| Enterprise Value | $6.3B | $4.2B | $6.1B | $4.3B | $3.8B | $2.0B | $887M | $924M | $771M | $987M | $508M |
| P/E Ratio → | 30.15 | 19.52 | 20.52 | 13.33 | 127.40 | — | — | 25.96 | 15.19 | 6.45 | 10.49 |
| P/S Ratio | 4.34 | 2.95 | 4.18 | 3.36 | 3.85 | 4.59 | 2.15 | 2.37 | 1.80 | 2.40 | 0.93 |
| P/B Ratio | 6.46 | 4.18 | 5.89 | 5.34 | 8.05 | 4.20 | 1.42 | 7.18 | 8.71 | 34.15 | — |
| P/FCF | 18.91 | 12.87 | 13.00 | 16.83 | 13.67 | 46.67 | 186.20 | 14.11 | 15.06 | 21.36 | 6.65 |
| P/OCF | 17.16 | 11.67 | 11.77 | 14.27 | 12.78 | 36.16 | 44.54 | 10.23 | 10.10 | 14.52 | 5.66 |
P/E links to full P/E history page with 30-year chart
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 2.72 | 3.99 | 3.28 | 4.03 | 4.80 | 2.61 | 2.66 | 2.25 | 2.98 | 1.68 |
| EV / EBITDA | 16.63 | 11.02 | 11.73 | 10.03 | 44.81 | — | 43.27 | 14.21 | 9.84 | 13.91 | 6.78 |
| EV / EBIT | 20.38 | 12.58 | 13.57 | 9.88 | 111.17 | — | — | 21.88 | 11.52 | 17.01 | 9.25 |
| EV / FCF | — | 11.85 | 12.40 | 16.46 | 14.31 | 48.89 | 226.05 | 15.85 | 18.78 | 26.51 | 12.02 |
Margins and return-on-capital ratios measuring operating efficiency
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 61.1% | 61.1% | 64.4% | 54.7% | 62.2% | 44.1% | 40.9% | 50.3% | 50.9% | 48.9% | 45.6% |
| Operating Margin | 20.2% | 20.2% | 29.8% | 28.1% | 3.9% | -14.3% | -1.2% | 14.9% | 18.8% | 15.6% | 18.7% |
| Net Profit Margin | 15.2% | 15.2% | 20.4% | 25.2% | 3.0% | -16.8% | -4.0% | 9.1% | 11.8% | 37.2% | 8.9% |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | 21.4% | 21.4% | 32.8% | 51.7% | 6.2% | -14.6% | -4.3% | 34.1% | 85.9% | 529.8% | — |
| ROA | 11.1% | 11.1% | 17.2% | 22.0% | 2.6% | -8.2% | -2.1% | 7.5% | 9.8% | 38.6% | 10.7% |
| ROIC | 30.6% | 30.6% | 45.3% | 41.0% | 4.6% | -7.4% | -0.7% | 17.6% | 22.0% | 23.2% | 32.6% |
| ROCE | 17.1% | 17.1% | 28.5% | 28.7% | 3.9% | -7.8% | -0.7% | 14.2% | 17.8% | 18.9% | 27.0% |
Solvency and debt-coverage ratios — lower is generally safer
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.00 | 0.00 | 0.57 | 0.76 | 1.30 | 0.41 | 0.46 | 1.70 | 3.75 | 11.51 | — |
| Debt / EBITDA | 0.00 | 0.00 | 1.19 | 1.45 | 6.94 | — | 11.51 | 2.99 | 3.40 | 3.78 | 3.72 |
| Net Debt / Equity | — | -0.33 | -0.27 | -0.12 | 0.38 | 0.20 | 0.30 | 0.89 | 2.16 | 8.24 | — |
| Net Debt / EBITDA | -0.94 | -0.94 | -0.56 | -0.23 | 2.00 | — | 7.63 | 1.56 | 1.95 | 2.70 | 3.03 |
| Debt / FCF | — | -1.01 | -0.59 | -0.37 | 0.64 | 2.22 | 39.85 | 1.74 | 3.73 | 5.15 | 5.37 |
| Interest Coverage | 16.89 | 16.89 | 22.91 | 21.53 | 4.72 | -8.68 | -0.21 | 3.10 | 3.85 | 3.15 | 2.06 |
Net cash position: cash ($359M) exceeds total debt ($738000)
Short-term solvency ratios and asset-utilisation metrics
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.70 | 2.70 | 5.52 | 5.80 | 2.74 | 2.61 | 2.29 | 2.62 | 3.70 | 3.16 | 2.53 |
| Quick Ratio | 2.51 | 2.51 | 5.23 | 5.45 | 2.59 | 2.22 | 1.84 | 2.17 | 3.08 | 2.60 | 2.13 |
| Cash Ratio | 1.08 | 1.08 | 3.80 | 3.81 | 1.68 | 1.09 | 0.99 | 1.41 | 2.15 | 1.63 | 1.17 |
| Asset Turnover | — | 0.69 | 0.77 | 0.79 | 0.71 | 0.49 | 0.39 | 0.86 | 0.78 | 0.86 | 1.18 |
| Inventory Turnover | 9.27 | 9.27 | 8.02 | 9.17 | 9.96 | 6.76 | 5.61 | 5.91 | 5.10 | 6.49 | 9.30 |
| Days Sales Outstanding | — | 84.91 | 76.44 | 80.04 | 83.30 | 76.69 | 58.07 | 45.74 | 46.51 | 44.34 | 44.52 |
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | 3.3% | 5.1% | 4.9% | 7.5% | 0.8% | — | — | 3.9% | 6.6% | 15.5% | 9.5% |
| FCF Yield | 5.3% | 7.8% | 7.7% | 5.9% | 7.3% | 2.1% | 0.5% | 7.1% | 6.6% | 4.7% | 15.0% |
| Buyback Yield | 4.5% | 6.6% | 1.6% | 0.0% | 2.1% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Total Shareholder Yield | 4.5% | 6.6% | 1.6% | 0.0% | 2.1% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Shares Outstanding | — | $68M | $72M | $70M | $71M | $67M | $54M | $40M | $40M | $39M | $33M |
Isotope supply chain dependency
Based on current market data, Lantheus trades at a forward P/E of 20.53, which suggests that investors are pricing in a transition from high-growth diagnostic adoption to a more mature, steady-state earnings profile as the PSMA imaging market faces increasing competitive pressure from new entrants.
The current valuation multiple appears to be a premium relative to traditional specialty pharma, yet it remains tempered by the inherent risks of isotope supply chain volatility. Investors should monitor whether the forward EV/EBITDA of 8.24 accurately captures the potential for margin compression if reimbursement models shift toward bundled payments.
According to historical financial data, the company's ROIC has trended downward from 14.5% in 2023Q4 to 5.8% in 2026Q1, indicating that recent capital deployments have struggled to generate the same level of incremental returns as the initial PYLARIFY commercialization phase observed in earlier periods.
This decline in capital efficiency warrants further investigation into whether the firm's recent M&A activity is diluting the returns of its core diagnostic franchise. The shift suggests that management may be entering a phase of diminishing marginal returns on invested capital as the competitive landscape for PSMA-targeting agents intensifies.
As reported in quarterly filings, the cash conversion cycle has fluctuated near 97 days as of 2026Q1, reflecting the logistical complexity of managing radiopharmaceuticals with extremely short half-lives that necessitate rapid inventory turnover and precise coordination with hospital-based diagnostic centers across the United States.
The elevated DSO of 85 days suggests that the company may be facing extended payment terms from hospital systems, which could pressure liquidity if not managed effectively. This working capital profile is structurally different from traditional drug manufacturers, as the inventory must be moved almost immediately upon production to avoid total loss.
Based on the most recent balance sheet, Lantheus has achieved a debt-to-equity ratio of 0.00, providing a significant financial fortress that insulates the company from interest rate volatility and allows for continued investment in the therapeutic pipeline despite the current deceleration in top-line revenue growth.
This lack of leverage is a critical differentiator compared to peers, offering management the flexibility to navigate potential supply chain shocks or regulatory reimbursement adjustments without the burden of debt service. Investors should view this as a defensive moat that supports long-term operational stability in a capital-intensive industry.
The P/E ratio is frequently misapplied to Lantheus because it fails to account for the high non-cash inventory write-offs and the unique 'use-it-or-lose-it' accounting nature of short-lived radiopharmaceuticals, which can create artificial volatility in reported net income that does not reflect true underlying cash generation.
Analysts should prioritize FCF-based metrics over P/E, as the latter obscures the company's ability to generate cash despite the accounting noise inherent in isotope distribution. Relying on P/E may lead to an incorrect assessment of the firm's earning power during periods of supply chain disruption or inventory obsolescence.
Includes 30+ ratios · 14 years · Updated daily
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Quick answers to the most common questions about buying LNTH stock.
Lantheus Holdings, Inc.'s current P/E ratio is 30.2x. The historical average is 29.9x. This places it at the 88th percentile of its historical range.
Lantheus Holdings, Inc.'s current EV/EBITDA is 16.6x. This enterprise value multiple compares the company's total value (equity + debt - cash) to its EBITDA. The historical average is 17.2x.
Lantheus Holdings, Inc.'s return on equity (ROE) is 21.4%. This is above the typical threshold of 15-20% considered good for most companies. The historical average is 26.7%.
Based on historical data, Lantheus Holdings, Inc. is trading at a P/E of 30.2x. This is at the 88th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
Lantheus Holdings, Inc. has 61.1% gross margin and 20.2% operating margin. Operating margin above 20% indicates strong pricing power and cost efficiency.
Lantheus Holdings, Inc.'s Debt/EBITDA ratio is 0.0x, indicating low leverage. A ratio below 2x is generally considered financially healthy.