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KALVKalVista Pharmaceuticals, Inc.
$27.00$1.4B
Overview & Verdict
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KALV logoKalVista Pharmaceuticals, Inc.(KALV)Earnings, Financials & Key Ratios

KALV•NASDAQ
$27.00
Price updated Jul 2, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryImmunology and Inflammation Therapies
AboutKalVista Pharmaceuticals, Inc., a clinical stage pharmaceutical company, discovers, develops, and commercializes small molecule protease inhibitors for diseases with unmet needs. The company's product portfolio comprises small molecule plasma kallikrein inhibitors targeting hereditary angioedema (HAE) and diabetic macular edema (DME); and oral plasma kallikrein inhibitors. Its products include KVD001, a plasma kallikrein inhibitor that completed a Phase II clinical trial for the treatment of DME; sebetralstat, which is initiation of the Phase 3 KONFIDENT trial as a potential oral, on-demand therapy for HAE attacks; KVD824, an oral product candidate for the treatment of HAE; and Factor XIIa, an oral inhibitor program which is in preclinical stage targets an enzyme in HAE. The company is headquartered in Cambridge, Massachusetts.Show more
  • Revenue$74M
  • EBITDA-$170M+8.9%
  • Net Income-$164M+10.4%
  • EPS (Diluted)-3.23+12.5%
  • Gross Margin91.75%
  • EBITDA Margin-231.45%
  • Operating Margin-233.42%
  • Net Margin-223.16%
  • ROE-354.52%-191.8%

KALV Price & Volume

KalVista Pharmaceuticals, Inc. (KALV) stock price & volume — 10-year historical chart

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Persistent Operating Losses Mask Structural Solvency Risks

Investment Thesis • Updated 2026Q4

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Strained
Cash Flow:Burning
Primary Risk:Commercialization and dilution risk

Key Thesis Takeaways

  • KalVista Pharmaceuticals faces a challenging transition from a milestone-dependent research entity to a commercial-stage biotechnology firm, characterized by significant operating losses and a deteriorating equity position.
  • While the company maintains a cash balance of $229.3 million, the rapid accumulation of debt to $151.6 million by 2026Q4 and the erosion of equity into negative territory at -$2.7 million raise concerns regarding long-term capital sustainability.
  • Investors should monitor the company's ability to generate recurring commercial revenue, as current financial performance remains heavily reliant on volatile, non-recurring milestone payments.

Verdict Logic

the company's reliance on non-recurring revenue and the shift to a debt-heavy capital structure, evidenced by a $151.6 million debt load against negative equity, suggests substantial execution and solvency risks.

KALV Growth Metrics

KalVista Pharmaceuticals, Inc. (KALV) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years42.49%
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM24.54%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM13.87%

Return on Capital

10 Years-59.75%
5 Years-67.75%
3 Years-78.25%
Last Year-71.06%

KALV Recent Earnings

KalVista Pharmaceuticals, Inc. (KALV) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 2/12 qtrs (17%)●Beat Revenue 1/12 qtrs (17%)
Q2 2026Latest
May 15, 2026
Metric
Actual
Est
EPS
$0.92-144.5%
$0.38
Rev
$14M-64.9%
$39M
Q2 2026
May 7, 2026
Metric
Actual
Est
EPS
$0.92-144.5%
$0.38
Rev
$14M-65.0%
$39M
Q2 2026
May 5, 2026
Metric
Actual
Est
EPS
$0.92-144.5%
$0.38
Rev
$14M-65.0%
$39M
Q2 2026
Mar 24, 2026
Metric
Actual
Est
EPS
$1.01-87.0%
$0.54
Rev
$1M-73.4%
$5M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 15, 2026
$0.92vs $0.38-144.5%
$14Mvs $39M-64.9%
Q2 2026May 7, 2026
$0.92vs $0.38-144.5%
$14Mvs $39M-65.0%
Q2 2026May 5, 2026
$0.92vs $0.38-144.5%
$14Mvs $39M-65.0%
Q2 2026Mar 24, 2026
$1.01vs $0.54-87.0%
$1Mvs $5M-73.4%
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for KalVista Pharmaceuticals, Inc. (KALV)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
KALV logoKALVKalVista Pharmaceuticals, Inc.Current
$27.00$1.44B-8.36—-223.16%-354.52%—
BDTX logoBDTXBlack Diamond Therapeutics, Inc.
$1.97$112.88M5.05——-36.37%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$313.50$9.06B-23.26-100%—-43.02%—
KALA logoKALAKALA BIO, Inc.
$1.54$33.77M-0.47——-1335.64%—
XOMA logoXOMAXOMA Royalty Corp.
$43.85$549.92M30.0383.06%86.97%30.21%—
AGEN logoAGENAgenus Inc.
$3.41$142M-1002.9410.37%52.16%——

Compare KALV vs Peers

KalVista Pharmaceuticals, Inc. (KALV) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs BDTX

Most directly comparable listed peer for KALV.

Scale Benchmark

vs MEDP

Larger-name benchmark to compare KALV against a more recognizable public peer.

Peer Set

Compare Top 5

vs BDTX, PRAX, KALA, XOMA

KALV SEC Filings & Documents

KalVista Pharmaceuticals, Inc. (KALV) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 29, 2026·SEC

Material company update

Mar 25, 2026·SEC

Material company update

Jan 8, 2026·SEC

10-K Annual Reports

2
FY 2025

Jul 10, 2025·SEC

FY 2024

Jul 11, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 14, 2026·SEC

FY 2025

Nov 10, 2025·SEC

FY 2025

Sep 11, 2025·SEC

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KALV Frequently Asked Questions

KalVista Pharmaceuticals, Inc. (KALV) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is KalVista Pharmaceuticals, Inc.'s revenue?

KalVista Pharmaceuticals, Inc. (KALV) reported $115.9M in revenue for fiscal year 2026. This represents a 7436% increase from $1.5M in 2013.

Is KALV profitable?

KalVista Pharmaceuticals, Inc. (KALV) reported a net loss of $138.4M for fiscal year 2026.

Dividend & Returns
What is KALV's return on equity?

KalVista Pharmaceuticals, Inc. (KALV) has a return on equity (ROE) of -354.5%. Negative ROE indicates the company is unprofitable.

What is KalVista Pharmaceuticals, Inc.'s free cash flow?

KalVista Pharmaceuticals, Inc. (KALV) had negative free cash flow of $23.8M in fiscal year 2026, likely due to heavy capital investments.

What if you invested $1,000 in KALV back in 2013?

Total return calculator · dividends reinvested · 13+ years of data

See returns →